Results 81 to 90 of about 9,336,073 (253)
The Hirschsprung's-multiple endocrine neoplasia connection
Clinics, 2012 The risk of patients with Hirschsprung's disease later developing multiple endocrine neoplasia remains a matter of concern. The multiple endocrine neoplasia 2-Hirschsprung's disease association has been shown to cosegregate in Hirschsprung's disease ...
Sam W. Moore, Monique Zaahl
doaj +1 more source
Peculiarities of Hirschsprung’s disease clinical course of newborns [PDF]
, 2016 Clinical case description Hirschsprung’s ...
Kolubakina, Larusa Viktorivna +1 more
core
Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 407-414, February 2026.Abstract Objectives Dolichocolon (DC), classified under International Classification of Diseases, Tenth Revision (ICD‐10) code Q43.8 (“Other specified congenital malformations of intestine”), refers to an elongated or redundant large intestine. Recent studies in adults indicate a role for dolichocolon in constipation and disorders of gut‐brain ...
David Simon +10 more
wiley +1 more source
Toxic megacolon: A rare presentation and novel treatment
JPGN Reports, Volume 7, Issue 1, Page 40-43, February 2026.Abstract A 14‐year‐old male presented with toxic megacolon (TM). Stool culture and rectal biopsies ruled out Clostridium difficile infection and Hirschsprung disease, respectively. Anorectal manometry ruled out anal achalasia as rectoanal inhibitory reflex elicited a normal resting pressure.
Adrienne P. Davis +3 more
wiley +1 more source
PLoS ONE, 2015 Hirschsprung’s disease (HSCR) is characterized by aganglionosis from failure of neural crest cell (NCC) migration to the distal hindgut. Up to 40% of HSCR patients suffer Hirschsprung’s-associated enterocolitis (HAEC), with an incidence that is unchanged
A. Gosain +6 more
semanticscholar +1 more source
JPGN Reports, Volume 7, Issue 1, Page 55-58, February 2026.ABSTRACT Severe refractory constipation can lead to fecal retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo‐obstruction but rarely for refractory constipation. Here, we report a 21‐year‐old male with chronic
Mojdeh Mostafavi +2 more
wiley +1 more source
The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]
, 2020 Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J +3 more
core
World Journal of Clinical Pediatrics, 2015 Hirschsprung's disease (HSCR) or congenital megacolon is one of the differential diagnoses of chronic constipation mostly in infancy and may indeed represent a challenge for pediatricians, pediatric surgeons, and pediatric pathologists.
C. Sergi
semanticscholar +1 more source
Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations
The Journal of Dermatology, Volume 53, Issue 2, Page 169-179, February 2026.ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley +1 more source
Zdorovʹe RebenkaBackground. Hirschsprung’s disease is one of the most common neonatal obstruction diseases. The annual cases of Hirschsprung’s disease in Indonesia are approximately 1,400 live births. Its screening and diagnosis can be established using several methods,
Illona Okvita Wiyogo +3 more
doaj +1 more source