Results 11 to 20 of about 3,329 (135)

Hirschsprung's Disease - Review of Clinical Features, Diagnosis and Treatment

Journal of Education, Health and Sport, 2023
Introduction and purpose: Hirschsprung's disease, also known as congenital aganglionic megacolon, is a rare congenital disorder that affects the large intestine.
Rafał Tkaczyk, Gabriela Świątek, Jakub Tomczyk, Weronika Sosnowska, Maria Tomkiewicz, Kalina Taracha, Maciej Tomkiewicz, Aleksandra Brzozowska, Kornelia Trusz, Iwona Wanat   +9 more
doaj   +1 more source

Hirschsprung’s Disease—Recent Understanding of Embryonic Aspects, Etiopathogenesis and Future Treatment Avenues

Medicina, 2020
Hirschsprung’s disease is a neurocristopathy, caused by defective migration, proliferation, differentiation and survival of neural crest cells, leading to gut aganglionosis. It usually manifests rapidly after birth, affecting 1 in 5000 live births around
Martin Klein, Ivan Varga
doaj   +1 more source

Maternal use of selective serotonin reuptake inhibitors during pregnancy is associated with Hirschsprung’s disease in newborns – a nationwide cohort study

Orphanet Journal of Rare Diseases, 2017
Background Hirschsprung’s disease is a rare condition caused by congenital malformation of the gastrointestinal tract affecting 1:5000 children. Not much is known about risk factors for development of Hirschsprung’s disease.
Sebastian Werngreen Nielsen, Perniller Møller Ljungdalh, Jan Nielsen, Bente Mertz Nørgård, Niels Qvist   +4 more
doaj   +1 more source

Delayed diagnosis of Hirschsprung's disease associated with colonic atresia and multiple anomalies: Report of a case and review of the literature

Journal of Pediatric Surgery Case Reports, 2016
The co-occurrence of colonic atresia and Hirschsprung's disease is extremely rare and presents a diagnostic and therapeutic challenge. Although colonic atresia is usually recognized shortly after birth, the diagnosis of co-existent Hirschsprung's disease
Jinyoung Park
doaj   +1 more source

A rare association of ileal atresia and total colonic Hirschsprung's disease

Journal of Pediatric Surgery Case Reports, 2022
Total colonic aganglionosis is the most rare form of Hirschsprung's disease and is defined as the absence of ganglion cells in both myenteric and submucosal plexus extending from the anus to at least the ileocecal valve. Intrauterine intussusceptions, on
Aida Daib, Maha Lindolsi, Youssef Hellal, Malek Boughdir, Rabiaa Ben Abdallah, Nejib Kaabar   +5 more
doaj   +1 more source

Predictability of 48-h delayed retention of contrast in barium enema in cases of chronic constipation

African Journal of Paediatric Surgery, 2020
Introduction: Diagnosis of Hirschsprung's disease depends on rectal biopsy. This study was designed to find an alternate diagnostic modality to exclude Hirschsprung's disease.
Nitin Sharma, Mini Sharma, Bhalendu Pratap Singh, Kunal Chandrakar, R K Chandrakar, Sewak Ram Verma   +5 more
doaj   +1 more source

Validity of Barium Enema as Hirschsprung’s Disease Diagnostic Tools for Infant in Sanglah Hospital Denpasar

JBN (Jurnal Bedah Nasional), 2021
Aim: To determine the validity (sensitivity, specificity, likelihood ratio) of barium enema as Hirschsprung's disease diagnostic tool in infants. Methods: This study was a diagnostic test of barium enema compared with postoperative histopathology ...
I Made Darmajaya, I Ketut Subhawa
doaj   +1 more source

A case of Hirschsprung's disease underwent surgery in adulthood

Journal of Pediatric Surgery Case Reports, 2016
Adult Hirschsprung's disease is a rare motor disorder of the gut that is frequently misdiagnosed as refractory constipation. We describe a 30-year-old patient with adult Hirschsprung's disease with a history of chronic constipation requiring daily enema.
Richi Nakatake, Yoshinori Hamada, Hirokazu Miki, Takeshi Shirai, Yusuke Nakamura, Hiroshi Hamada, Morihiko Ishizaki, Masanori Kon   +7 more
doaj   +1 more source

Neuroimmune regulation in Hirschsprung’s disease associated enterocolitis

Frontiers in Immunology, 2023
Neuroimmune pathways are important part of the regulation of inflammatory response. Nerve cells regulate the functions of various immune cells through neurotransmitters, and then participate in the inflammatory immune response. Hirschsprung’s disease (HD)
Haosen Ji, Dengming Lai, Jinfa Tou
doaj   +1 more source

Congenital intestinal hypoganglionosis: A radiologic mimic of Hirschsprung's disease

Radiology Case Reports, 2019
Intestinal hypoganglionosis or isolated hypoganglionosis is a rare entity with a clinical and radiologic presentation that can mimic Hirschsprung's disease in the neonatal period.
Gayathri Sreedher, MD, Aaron Garrison, MD, Robert Novak, MD, FAAP, Matthew Keisling, DO, FCAP, FASCP, Shankar Srinivas Ganapathy, MD   +4 more
doaj   +1 more source