Results 61 to 70 of about 9,333,061 (296)

Interrater reliability in pediatric high‐resolution anorectal manometry recordings

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives High‐resolution anorectal manometry (HR‐ARM) is a diagnostic test assessing anorectal neuromuscular function in children with constipation and/or fecal incontinence. Interrater reliability of HR‐ARM in children has not been previously studied. The aim of this study was to assess the interrater reliability of pediatric HR‐ARM studies.
Julia M. J. van der Zande, Marc A. Benninga, Bruno P. Chumpitazi, Anil Darbari, Jose M. Garza, Julie Khlevner, Samuel Nurko, Miguel Saps, Karla Vaz, Sujithra Velayuthan, Md Rejuan Haque, Carlo Di Lorenzo, Peter L. Lu   +12 more
wiley   +1 more source

Hirschsprung disease and hepatoblastoma: case report of a rare association

São Paulo Medical Journal
CONTEXT: Hirschsprung disease is a developmental disorder of the enteric nervous system that is characterized by absence of ganglion cells in the distal intestine, and it occurs in approximately 1 in every 500,000 live births.
Raquel Borges Pinto, Ana Regina Lima Ramos, Ariane Nadia Backes, Beatriz John dos Santos, Valentina Oliveira Provenzi, Mário Rafael Carbonera, Maria Lúcia Roenick, Pedro Paulo Albino dos Santos, Fabrizia Falhauber, Meriene Viquetti de Souza, João Vicente Bassols, Osvaldo Artigalás   +11 more
doaj   +1 more source

High-resolution anorectal manometry in children [PDF]

Clinical and Experimental Pediatrics
Anorectal manometry is one of the motility tests in children performed by pediatric gastroenterologist. It evaluates the motility function of anorectal tract.
Yogesh Waikar
doaj   +1 more source

Enzymhistochemie des klassischen und des ultrakurzen Morbus Hirschsprung [PDF]

, 2018
Zusammenfassung: Der M.Hirschsprung bildet die wichtigste gastrointestinale Motilitätsstörung in der frühkindlichen pathologischen Diagnostik. Die fehlerhafte kraniokaudale Migration der aus der Neuralleiste stammenden Neuroblastenvorläuferzellen führt ...
Bruder, E., Meier-Ruge, W.A., Passarge, E., Terracciano, L.M.   +3 more
core  

Outcomes in patients with Hirschsprung disease following definitive surgery

BMC Research Notes, 2018
Several pull-through procedures have been described for Hirschsprung disease (HSCR) with varying outcomes. We aimed to describe the outcomes in HSCR patients
Gunadi, Stefani Melisa Karina, Andi Dwihantoro   +2 more
semanticscholar   +1 more source

Toxic megacolon: A rare presentation and novel treatment

JPGN Reports, EarlyView.
Abstract A 14‐year‐old male presented with toxic megacolon (TM). Stool culture and rectal biopsies ruled out Clostridium difficile infection and Hirschsprung disease, respectively. Anorectal manometry ruled out anal achalasia as rectoanal inhibitory reflex elicited a normal resting pressure.
Adrienne P. Davis, Jennifer M. Schuh, Janice Bitong, Amy J. Wagner   +3 more
wiley   +1 more source

ZwanzigJahre diagnostisches Hirschsprung-Kompetenzzentrum in Basel [PDF]

, 2018
Zusammenfassung: Hintergrund: In vorliegendem Bericht werden die in 20 Jahren gesammelten Erfahrungen des Basler Hirschsprung-Kompetenzzentrums zusammengestellt. Methodik: Zwischen 1987 und 2006 wurden 19.365 Rektumschleimhautbiopsien untersucht.
Bruder, E., Meier-Ruge, W. A.
core  

Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function [PDF]

, 2017
ACKGROUND & AIMS: Hirschsprung disease is caused by failure of enteric neural crest cells (ENCCs) to fully colonize the bowel, leading to bowel obstruction and megacolon. Heterozygous mutations in the coding region of the RET gene cause a severe form of
Garcia-Barcelo, MM, Gui, H, Lai, FPL, Lai, KWH, Lau, CST, Ngan, ESW, Tam, PKH, Tse, HF, Wang, X, Wong, JKL, Zhou, T   +10 more
core   +1 more source

When manual disimpaction isn't enough: Case report and review of neostigmine's role in refractory constipation management

JPGN Reports, EarlyView.
ABSTRACT Severe refractory constipation can lead to fecal retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo‐obstruction but rarely for refractory constipation. Here, we report a 21‐year‐old male with chronic
Mojdeh Mostafavi, Sarah Lee, Victoria Martin   +2 more
wiley   +1 more source

Total colonic aganglionosis and cleft palate in a newborn with Janus-cysteine 618 mutation of RET proto-oncogene: a case report

Italian Journal of Pediatrics, 2020
Background Hirschsprung disease, the most important congenital colonic dysmotility in children results from neural crest migration, differentiation, proliferation, or apoptosis defects where the rearranged during transfection (RET)-Protooncogene pathway ...
Ingrid Anne Mandy Schierz, Marcello Cimador, Mario Giuffrè, Claudia Maria Aiello, Vincenzo Antona, Giovanni Corsello, Ettore Piro   +6 more
doaj   +1 more source