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Histamine Pharmacogenomics

Pharmacogenomics, 2009
Genetic polymorphisms for histamine-metabolizing enzymes are responsible for interindividual variation in histamine metabolism and are associated with diverse diseases. Initial reports on polymorphisms of histamine-related genes including those coding for the enzymes histidine decarboxylase (HDC), diamine oxidase (ABP1) and histamine N ...
Elena, García-Martín   +4 more
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Histamine releasing factors

Clinical & Experimental Allergy, 1991
Histamine-releasing factors (HRF) are cell-derived products which cause histamine release from basophils and/or mast cells. We have isolated HRF from human mononuclear cells and platelets and have purified 3 molecular species having molecular weights of 8–10, 15–17 and 35–41 kilodaltons (kDa).
A P, Kaplan   +3 more
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Natural histamines

General Pharmacology: The Vascular System, 1976
Twelve histamines have been so far identified in living animal tissues. The two reactive sites of the histamine molecule involved in the production of these derivatives are represented by the imino nitrogen of the nucleus and the amino group of the lateral chain.
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Histamine and Histamine Antagonists

1991
Together with the two previous volumes of the "Handbook of Experimental Pharmacology" on histamine and antihistamines (volume 18, part 1, 1966 and part 2, 1978), the present volume yields a picture of a still rapidly developing field of research. It covers the process in histamine research during the past two decades. As a result of a consensus meeting
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Histamine and the stomach: chemical histamine assays

Scandinavian journal of gastroenterology. Supplement, 1991
Histamine assays in gastroduodenal tissues and body fluids are not an absolute objective of scientific interest but are related to the role of histamine in health and disease. Hence, the reliability of histamine assays has to be assessed in relation to this aim.
Lorenz, Wilfried   +6 more
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Studies on histamine and histamine antagonists

Journal of Allergy, 1948
Abstract 1.1. The results of some experiments on histamine and antihistaminic drugs in allergic patients were reported. 2.2. A histamine release from allergic skin reactions was shown. 3.3. A disturbed histamine metabolism was shown in allergic patients by an increase of blood histamine after histamine injection (histamine tolerance curve) and ...
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Histamine and Methyl-Histamine

1995
Histamine is widely distributed throughout all tissues although its main sites of synthesis and storage are the tissue mast cell and the blood basophil. Histamine is synthesized from histidine by a specific decarboxylase and stored in the secretory granules. On activation of the cells histamine is released by degranulation.
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Histamine, histamine antagonists and regional blood flow

European Journal of Pharmacology, 1977
The effects of mepyramine, a selective histamine H1-receptor antagonist, and metiamide, a selective histamine H2-receptor antagonist, have been determined on the cardiovascular response to intravenous infusions of a large dose of histamine, 1 X 10(-7) mol/kg/min.
B M, Johnston, D A, Owen
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Histamine

Annual Review of Pharmacology, 1965
G, KAHLSON, E, ROSENGREN
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Histamine and Histamine Receptors in Allergic Dermatitis

2016
In this chapter we will first introduce the pathophysiological process of several skin diseases including allergic dermatitis, a common skin disease, including chronic allergic contact dermatitis (CACD), and atopic dermatitis (AD). In CACD and AD patients, repeated skin exposure to antigens contributes to the development of chronic eczematous lesions ...
Hiroshi, Ohtsu, Masahiro, Seike
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