First description of a histamine receptor of class 2 (HRH2) in a protochordate: expression during blastogenesis and role in regulation of ciliary beat frequency [PDF]
Histaminergic receptors belong to the family of seven-transmembrane \u3b1-helix domain receptors classified in mammals into four distinct classes. Despite being widely studied in vertebrates, few data are available on the invertebrate receptors, with ...
Cima, Francesca
core
The Immunological Correlation With Adenoid Hypertrophy and Allergic Rhinitis in Children
The imbalance of Th1/Th2 and Th17/Treg cells in allergen and inflammatory responses might be associated with the development of adenoid hypertrophy, suggesting that allergic rhinitis maybe the risk factor of AH and providing a potential alternative explanation for adenoid hypertrophy pathogenesis.
Yang Song +4 more
wiley +1 more source
Introduction: Histamine administered intracerebroventricularly (icv) induces a resuscitating effect in hemorrhage-shocked rats. Dopamine receptors are present in neuronal pathways involved in central cardiovascular regulation; therefore, the aim of the ...
Karolina Jasikowska +5 more
doaj +1 more source
Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S +6 more
core +1 more source
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley +1 more source
Background: Although β-adrenergic receptor agonists inhibit antigen-induced release of histamine, leukotrienes and prostaglandin D2 from human lung fragments, dispersed human lung mast cells and human skin mast cells, subcellular mechanisms for the ...
Toshinobu Kato +8 more
doaj +1 more source
Long-term effects of allergen sensitization and exposure in adult asthma: a prospective study. [PDF]
BACKGROUND: : We investigated the effects of sensitization and exposure to common domestic allergens on longitudinal changes in lung function and bronchial hyperresponsiveness. METHODS: : Subjects attended 2 visits that were 4 years apart.
Adnan Custovic +30 more
core +1 more source
Alginate Therapy for Gastroesophageal Reflux in Pregnancy: A Scoping Review
ABSTRACT Objective Alginate therapies are a promising option for managing gastroesophageal reflux (GERD), but most treatments are not recommended during pregnancy. This scoping review aimed to summarize the current outcomes research on the use of alginate therapy for treating GERD during pregnancy.
Maya Senthilkumaran +5 more
wiley +1 more source
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms [PDF]
The mechanisms that generate itch are poorly understood at both the molecular and cellular levels despite its clinical importance. To explore the peripheral neuronal mechanisms underlying itch, we assessed the behavioral responses (scratching) produced ...
A. I. Basbaum +32 more
core +2 more sources
Mouse Vocal Fold Permeability In Vivo: Effects of Novel Low‐Tech Injury and Instillation Methods
Improving experimental mouse vocal fold injury and instillation approaches is necessary to advance preclinical models of laryngeal disease. We have successfully repurposed low‐tech, quick, and reliable injury and instillation methods established in respiratory research. Using these methods, we show that murine vocal fold epithelium is inherently highly
Renee E. King +2 more
wiley +1 more source

