Results 101 to 110 of about 126,927 (355)

The Immunological Correlation With Adenoid Hypertrophy and Allergic Rhinitis in Children

iNew Medicine, EarlyView.
The imbalance of Th1/Th2 and Th17/Treg cells in allergen and inflammatory responses might be associated with the development of adenoid hypertrophy, suggesting that allergic rhinitis maybe the risk factor of AH and providing a potential alternative explanation for adenoid hypertrophy pathogenesis.
Yang Song, Chao Zhang, Jun Song, Jian‐Ming Yang, Wei Wei   +4 more
wiley   +1 more source

Role of orexin receptors in histamine- and chloroquine-induced pruriceptive processing

Neuroscience Research
It is known that orexin peptides are involved in nociceptive processing, while little is known about the roles of these peptides in itch processing. To reveal the functions of orexin peptides in pruriceptive processing, orexin A (OX-A) and orexin B (OX-B)
Anna Kanemaru-Kawazoe, Hideki Funahashi, Yoichiro Kogoh, Ayaka Haruta-Tsukamoto, Yu Miyahara, Toshikazu Nishimori, Yasushi Ishida, Yoji Hirano   +7 more
doaj   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science
Amyloid‐beta (Aβ) and hyperphosphorylated tau (p‐tau) aggregation are hallmark pathogenic events in Alzheimer's disease (AD). Microglial clearance of these toxic aggregates is essential, yet the underlying mechanisms remain poorly understood.
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
doaj   +2 more sources

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source

Proliferative Effects of Histamine on Primary Human Pterygium Fibroblasts

Mediators of Inflammation, 2016
Purpose. It has been confirmed that inflammatory cytokines are involved in the progression of pterygium. Histamine can enhance proliferation and migration of many cells.
Zhenwei Qin, Qiuli Fu, Lifang Zhang, Houfa Yin, Xiuming Jin, Qiaomei Tang, Danni Lyu, Ke Yao   +7 more
doaj   +1 more source

Suppression of Histamine Signaling by Probiotic Lac-B: a Possible Mechanism of Its Anti-allergic Effect

Journal of Pharmacological Sciences, 2008
It has been shown that probiotic bacteria are effective for the treatment of allergic diseases. As histamine plays a central role in allergic diseases, it is possible that probiotic bacteria affect the allergy-related histamine signaling.
Shrabanti Dev, Hiroyuki Mizuguchi, Asish K. Das, Chiyo Matsushita, Kazutaka Maeyama, Hayato Umehara, Takayuki Ohtoshi, Jun Kojima, Kiyotaka Nishida, Kunihiko Takahashi, Hiroyuki Fukui   +10 more
doaj   +1 more source

Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]

, 2004
Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C., Laakmann, G., Schule, C.   +2 more
core   +1 more source

Alginate Therapy for Gastroesophageal Reflux in Pregnancy: A Scoping Review

The Laryngoscope, EarlyView.
ABSTRACT Objective Alginate therapies are a promising option for managing gastroesophageal reflux (GERD), but most treatments are not recommended during pregnancy. This scoping review aimed to summarize the current outcomes research on the use of alginate therapy for treating GERD during pregnancy.
Maya Senthilkumaran, Kaitlyn Hui, Corey Li, Sophia Werden‐Abrams, Phillip Staibano, Benjamin van der Woerd   +5 more
wiley   +1 more source

Multiple Targeting Approaches on Histamine H3 Receptor Antagonists

Frontiers in Neuroscience, 2016
With the very recent market approval of pitolisant (Wakix®), the interest in clinical applications of novel multifunctional histamine H3 receptor antagonists has clearly increased. Since histamine H3 receptor antagonists in clinical development have been
Mohammad eKhanfar, Anna eAffini, Kiril eLutsenko, Katarina eNikolic, Stefania eButini, Holger eStark   +5 more
doaj   +1 more source

Mouse Vocal Fold Permeability In Vivo: Effects of Novel Low‐Tech Injury and Instillation Methods

The Laryngoscope, EarlyView.
Improving experimental mouse vocal fold injury and instillation approaches is necessary to advance preclinical models of laryngeal disease. We have successfully repurposed low‐tech, quick, and reliable injury and instillation methods established in respiratory research. Using these methods, we show that murine vocal fold epithelium is inherently highly
Renee E. King, Ella T. Ward‐Shaw, Paul F. Lambert   +2 more
wiley   +1 more source