Results 131 to 140 of about 119,292 (306)

Postauricular Skin Mycobiome Profiles in Atopic Dermatitis Treated With Dupilumab or Cyclosporine A: A Descriptive Case Series

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) essentially exhibits dysbiosis of skin fungal microbiome, mycobiome, characterized by depletion of Malassezia. The effects of recent systemic therapies for AD on skin mycobiome were not understood enough. We examined changes of skin mycobiome before and after systemic treatments with anti‐IL‐4Rα antibody (dupilumab: DUP)
Yuta Koike, Hitomi Morisaki, Daisuke Motooka, Mai Matsumoto, Motoi Takenaka, Hiroyuki Murota   +5 more
wiley   +1 more source

Structural basis for recognition of antihistamine drug by human histamine receptor. [PDF]

Nat Commun, 2022
Peng X, Yang L, Liu Z, Lou S, Mei S, Li M, Chen Z, Zhang H.   +7 more
europepmc   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Release of histamine by H2-receptor antagonists [PDF]

, 1987
Dietz, W., Doenicke, A., Lorenz, Wilfried   +2 more
core   +1 more source

Discovery of 8-Hydroxyquinoline as a Histamine Receptor 2 Blocker Scaffold. [PDF]

ACS Synth Biol, 2022
Marquez-Gomez PL, Kruyer NS, Eisen SL, Torp LR, Howie RL, Jones EV, France S, Peralta-Yahya P.   +7 more
europepmc   +1 more source

Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)

Allergy, EarlyView.
This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.
Qingxiu Xu, Xuan Yuan, Wang Liao, Hao Chen, Qing Jiang, Lin Yang, Jin Liu, Le Li, Nan Huang, Wenjing Li, Yaqi Yang, Dongxia Ma, Jun Bai, Zhihai Xie, Rongfei Zhu   +14 more
wiley   +1 more source

Component-Resolved in Vitro Diagnosis in Peach-Allergic Patients [PDF]

, 2009
BACKGROUND: The in vitro diagnosis of pollen-related food allergy presents low specifi city and reproducibility with many conventional extracts. This can be improved using natural purifi ed allergens, recombinant purifi ed allergens, or both.
Antepara, I., Barber, Domingo, Ferrer, M., Gamboa, P.M., Goikoetxea, M.J., Lombardero, M., Salcedo Duran, Gabriel, Sanz, M.L., Sánchez-Monge Laguna de Rins, Rosa   +8 more
core   +1 more source

Nuclear localization of histamine receptor 2 in primary human lymphatic endothelial cells. [PDF]

Biol Open, 2022
Pal S, Gashev A, Roy D.
europepmc   +1 more source

Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration. [PDF]

Sci Rep, 2023
Park C, Lee JW, Kim K, Seen DS, Jeong JY, Huh WK.   +5 more
europepmc   +1 more source

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

Allergy, EarlyView.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger, Carolin Költgen, Magda Babina, Peter Wolf   +3 more
wiley   +1 more source