Serotonin as a Creativity Pump [PDF]
arXivThe location of Western Civilization defined nations in Europe and in the United States within the largest global pollen environments on the planet is proposed as a key factor leading to their success. Environments with dense pollen concentrations will cause large up and down changes in serum histamine directly causing reductions and increases in brain
arxiv
Chemical sensing by cell-surface chemoreceptor arrays: the roles of receptor cooperativity and adaptation [PDF]
arXiv, 2012 Most sensory cells use cross-membrane chemoreceptors to detect chemical signals in the environment. The biochemical properties and spatial organization of chemoreceptors play important roles in achieving and maintaining sensitivity and accuracy of chemical sensing.
arxiv
Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments
Med Research, EarlyView.ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li +13 more
wiley +1 more source
Insight into the Mode of Action of 8-Hydroxyquinoline-Based Blockers on the Histamine Receptor 2. [PDF]
Biosensors (Basel), 2023 Patel A +4 more
europepmc +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar +4 more
wiley +1 more source
Histamine H1‐receptor‐mediated modulation of NMDA receptors signaling responses
Pharmacology Research & PerspectivesThis study attempted to clarify the role of histamine H1 receptors in epilepsy by exploring the effects of agonists and inverse agonists on the rundown of the current induced by iterative applications of NMDA or GABA in primary neuronal culture ...
J.‐M. Arrang, V. Armand
doaj +1 more source
Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1
MicrobiologyOpen, 2019 The histamine H2 receptor (H2R) is a G protein‐coupled receptor that mediates cyclic AMP production, protein kinase A activation, and MAP kinase signaling.
Robert Fultz +9 more
doaj +1 more source
The Roles of Histamine Receptor 1 (hrh1) in Neurotransmitter System Regulation, Behavior, and Neurogenesis in Zebrafish. [PDF]
Mol Neurobiol, 2023 Yao Y +4 more
europepmc +1 more source
Alterations in histamine responses between juvenile and adult urinary bladder urothelium, lamina propria and detrusor tissues [PDF]
, 2020 Chess-Williams, Russ +2 more
core +1 more source
Calcium puffs are generic InsP3-activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses [PDF]
, 2001 Elementary Ca2+ signals, such as "Ca2+ puffs", which arise from the activation of inositol 1,4,5-trisphosphate receptors, are building blocks for local and global Ca2+ signalling.
Berridge, Michael J. +11 more
core