Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration. [PDF]
Sci Rep, 2023 Park C +5 more
europepmc +1 more source
Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research
United European Gastroenterology Journal, EarlyView.ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch +1 more
wiley +1 more source
Regulatory Perspective Reverse Engineering Analysis of the Mast Cell Stabilizer and the Histamine Receptor Antagonist (Olopatadine HCl): Instrumental and Classical Methods for Multiple Formulations. [PDF]
ACS Omega, 2023 Kowtharapu LP +6 more
europepmc +1 more source
Deciphering the panvascular immune landscape of atherosclerosis
VIEW, EarlyView.Atherosclerosis (AS) involves inflammation in major arteries and can cause severe cardiovascular events like heart attacks and strokes, yet disease patterns vary significantly between arteries, complicating diagnosis and treatment. In this study, we integrated transcriptomic and single‐cell RNA sequencing data from AS plaques across five key arterial ...
Yiming Zhong +12 more
wiley +1 more source
Histamine and histamine receptor H1 (HRH1) axis: new target for enhancing immunotherapy response. [PDF]
Mol Biomed, 2022 Bai Z, Ai J, Wei X.
europepmc +1 more source
The Effects of Histamine H3 Receptors on Contractile Responses on Rat Gastric Fundus [PDF]
, 2006 The aim of this study is to determine the effects of histamine receptors on the gastrointestinal system smooth muscle contractions and the role of histamine H3 receptors on these effects.
Aşkın Hekimoğlu, Ramazan Çiçek
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FASEB BioAdvances, EarlyView.Deuterium, a heavy isotope of hydrogen, is universal in nature, but it disrupts the mitochondrial ATPase pumps. One mechanism that biological organisms may use to reduce deuterium levels in the mitochondria is to sequester deuterium bound to carbon atoms in a small set of organic molecules that have a unique configuration to support such trapping ...
Stephanie Seneff +2 more
wiley +1 more source
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Most studies of trade‐offs between defence, growth and reproduction have examined pairwise correlations between these processes, used ratio‐based measures for defence allocation such as allelochemical concentration and trichome density and estimated resource allocation ...
Inori Yuuzaki +2 more
wiley +1 more source
Maprotiline restores ER homeostasis and rescues neurodegeneration via Histamine Receptor H1 inhibition in retinal ganglion cells. [PDF]
Nat Commun, 2022 Chen W +10 more
europepmc +1 more source
Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. [PDF]
, 1998 We investigated the role of Bruton's tyrosine kinase (Btk) in FcepsilonRI-dependent activation of mouse mast cells, using xid and btk null mutant mice.
Alt, FW +16 more
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