Dual-Histamine Receptor Blockade with Cetirizine - Famotidine Reduces Pulmonary Symptoms in COVID-19 Patients [PDF]
Hogan RB+6 more
europepmc +2 more sources
The second-generation histamine-H1-receptor antagonists, such as epinastine and cetirizine, are used as non-sedating antihistamines for treating allergic symptoms due to their poor ability to penetrate blood-brain barrier.
Junzo Kamei+4 more
doaj
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
In vitro effects of histamine receptor 1 antagonists on proliferation and histamine release in canine neoplastic mast cells. [PDF]
Gamperl S+4 more
europepmc +1 more source
Arrestin‐centred interactions at the membrane and their conformational determinants
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood+3 more
wiley +1 more source
Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H2-histamine-receptor activation in isolated atria of transgenic mice. [PDF]
Neumann J+4 more
europepmc +1 more source
Definition and classification of the histamine-release response to drugs in anaesthesia and surgery: studies in the conscious human subject [PDF]
Doenicke, A.+5 more
core +1 more source
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison+15 more
wiley +1 more source
Introduction/Aims: The nucleus accumbens (NAc) receives histaminergic neurons from tuberomammillary nuclei. There are also reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Mohammad-Reza Zarrindast+2 more
doaj
Effects of Histamine Receptor Antagonist Cetirizine on Orthodontic Tooth Movement. [PDF]
Sperl G+6 more
europepmc +1 more source