Results 41 to 50 of about 111,103 (336)

Cytokine responses of intraepithelial lymphocytes are regulated by histamine H2 receptor [PDF]

, 2009
Backgrounds. Histamine participates in the immune regulation of several gastrointestinal diseases. However, the effect of histamine on intestinal intraepithelial lymphocytes (IELs), the front line of intestinal mucosal immune system, is not well ...
A Di Sabatino, A Hayday, A Mazzoni, Akira Hishida, B Lagier, C Lundqvist, CA Akdis, CA Akdis, CC Fox, D Montufar-Solis, E Bolton, E Masini, G Barbara, G Caron, G Monteleone, H Cheroutre, H Cheroutre, H Kiyono, HD Lim, HK Takahashi, IJ Elenkov, K Hoshino, K Takahashi, K Tomita, Kosuke Takagaki, L Knutson, L Lefrancois, LB Hough, LB Svendsen, LE Sander, M Jutel, M Kawaguchi, M Watanabe, Mutsuhiro Ikuma, N Osna, N Osna, P Parronchi, R Boismenu, R Leurs, RL Mosley, S Bischoff, S Kapoor, S Matsumoto, S Takamatsu, S Winterkamp, Satoshi Osawa, T Morichika, T Taguchi, T Taguchi, TA Barrett, Takahisa Furuta, Takanori Yamada, WJ Adams, WJ Adams, Y Horio, Y Sonobe, Yasuhiro Takayanagi, Yasushi Hamaya, Yoshiaki Horio   +58 more
core   +1 more source

Trafficking of carbonic anhydrase 12 and bicarbonate transporters by histamine stimulation mediates intracellular acidic scenario in lung cancer cells

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Carbonic anhydrase 12 is considered an oncogenic and acidic microenvironmental factor in cancer cells. To verify the role of histamine signalling as an anti-cancer signal, we determined the roles of CA12 and its associated bicarbonate transporters.
Hyeong jae Kim, Jeong Hee Hong
doaj   +1 more source

Algebraic study of receptor-ligand systems: a dose-response analysis [PDF]

arXiv, 2022
The study of a receptor-ligand system generally relies on the analysis of its dose-response (or concentration-effect) curve, which quantifies the relation between ligand concentration and the biological effect (or cellular response) induced when binding its specific cell surface receptor.
arxiv  

Anti-Allergic Cromones Inhibit Histamine and Eicosanoid Release from Activated Human and Murine Mast Cells by Releasing Annexin A1 [PDF]

, 2013
PMCID: PMC3601088This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Ahluwalia, A Mulla, AB Kay, Ajantha Sinniah, AM Lucas, Bernhard Ryffel, C Bandeira-Melo, C Dahl, CD John, CF Schwender, CF Schwender, CP Sung, CP Sung, DS Thomson, E Solito, E Solito, E Wells, EB Cook, Egle Solito, F D'Acquisto, FL Pearce, FN Gavins, FS Ng, G Folkerts, G Galatowicz, J Raud, JD Croxtall, JP Tarayre, JP Tarayre, JP Tarayre, JS Cox, JS Cox, JS Cox, JS Cox, K Kuriyama, L Jenkins, L Wang, M Corbel, M Perretti, M Shichijo, MK Church, NJ Goulding, PJ Barnes, R Sagi-Eisenberg, RH Grace, RJ Rintala, RM Viscardi, Rod J. Flower, RP Hayhoe, S Mattoli, S Murphy, S Pieretti, S Yazid, S Yazid, Samia Yazid, SH Lee, SH Peers, SI Wasserman, SilvaJR Lapa e, SK Bansal, SM Oliani, T Du, T Oka, T Radeau, TC Theoharides, TC Theoharides, TW Evans, Virginia Calder, WM Abraham, WM Abraham, Y Okayama, Y Yang, Y Zuo, YW Chung   +73 more
core   +2 more sources

Histamine receptors in GtoPdb v.2021.3 [PDF]

, 2021
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 173]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and rat
Chazot, Paul, Cowart, Marlon, Fukui, Hiroyuki, Ganellin, C. Robin, Gutzmer, Ralf, Haas, Helmut L., Hill, Stephen J., Hills, Rebecca, Leurs, Rob, Levi, Roberto, Liu, Steve, Panula, Pertti, Schunack, Walter, Schwartz, Jean-Charles, Seifert, Roland, Shankley, Nigel P., Stark, Holger, Thurmond, Robin, Timmerman, Henk, Young, J. Michael   +19 more
core   +2 more sources

Method for identification of condition-associated public antigen receptor sequences [PDF]

eLife 2018;7:e33050, 2017
Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences.
arxiv   +1 more source

Regulation of Neuromodulator Receptor Efficacy - Implications for Whole-Neuron and Synaptic Plasticity [PDF]

Progress in Neurobiology 72(6), pp 399-415, April 2004, 2004
Membrane receptors for neuromodulators (NM) are highly regulated in their distribution and efficacy - a phenomenon which influences the individual cell's response to central signals of NM release. Even though NM receptor regulation is implicated in the pharmacological action of many drugs, and is also known to be influenced by various environmental ...
arxiv   +1 more source

Neurochemical characterization of pERK-expressing spinal neurons in histamine-induced itch [PDF]

, 2015
Date of Acceptance: 08/07/2015 Acknowledgements This work was supported by grants from the Ministry of Science and Technology of China (2012CB966904, 2011CB51005), National Natural Science Foundation of China (31271182, 81200692, 91232724, 81200933 ...
Chai, Guo-Dong, Chen, Jia-Yin, Chen, Ling, Dai, Meng-Han, Ding, Yu-Qiang, Huang, Kun, Jiang, Guan-Yu, Lang, Bing, McCaig, Colin, St Clair, David, Wang, Qing-Xiu, Zhang, Ling   +11 more
core   +1 more source

Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation [PDF]

, 2019
Histamine [2-(4-Imidazolyl)-ethylamine] modulates different biological processes, through histamine H1 and H2 receptors, and their respective blockers are widely used in treating allergic and gastric acid-related disorders.
Burghi, Valeria, Davio, Carlos Alberto, Díaz, Antonela Susana, Fernandez, Natalia Cristina, Monczor, Federico, Rodriguez Gonzalez, Angela Paola, Sahores, Ana, Shayo, Carina Claudia, Sosa, Máximo Hernán, Zappia, Carlos Daniel   +9 more
core   +1 more source

Histamine receptors in mammalian retinas [PDF]

Journal of Comparative Neurology, 2006
AbstractMammalian retinas are innervated by histaminergic axons that originate from perikarya in the posterior hypothalamus. To identify the targets of these retinopetal axons, we localized histamine receptors (HR) in monkey and rat retinas by light and electron microscopy.
Noga Vardi, Alistair J. Barber, David W. Marshak, Matthew J. Gastinger   +3 more
openaire   +3 more sources