Results 71 to 80 of about 111,103 (336)
BMC Medicine, 2012 Corticosteroids are standard treatment for patients with multiple sclerosis experiencing acute relapse. Because dyspeptic pain is a common side effect of this intervention, patients can be given a histamine receptor-2 antagonist, proton pump inhibitor or
Biswas Sangita +3 more
doaj +1 more source
Cargo binding promotes KDEL receptor clustering at the mammalian cell surface [PDF]
Sci. Rep. 6, 28940, 2016, 2017 Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor cluster formation has been described for a wide variety of receptors, ranging from chemotactic receptors in bacteria to ...
arxiv +1 more source
Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons [PDF]
, 2016 Zolpidem, a GABAA receptor-positive modulator, is the gold-standard drug for treating insomnia. Zolpidem prolongs IPSCs to decrease sleep latency and increase sleep time, effects that depend on α2 and/or α3 subunit-containing receptors.
Brickley, SG +9 more
core +4 more sources
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source
Journal of Pharmacological Sciences, 2006 .: G-protein-coupled receptors (GPCR) represent a large and diverse superfamily of integral membrane proteins to which histamine receptors belong. Increasing numbers of proteins have been identified to interact with the C-termini of GPCRs.
Kuramasu Atsuo +3 more
doaj
Indomethacin-antihistamine combination for gastric ulceration control [PDF]
, 1981 An anti-inflammatory and analgesic composition containing indomethacin and an H sub 1 or an H sub 2 histamine receptor antagonist in an amount sufficient to reduce gastric distress caused by the indomethacin is described.
Brown, P. A., Danellis, J. V.
core +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT Chronic inflammation can lead to various diseases, including gastric ulcers, highlighting the need for effective therapeutic strategies. The traditional use of Chamaerops humilis in Moroccan folk medicine for treating gastrointestinal disorders underscores its potential as a valuable natural remedy.
Yasmina Jaouhari +12 more
wiley +1 more source
Polar Chemoreceptor Clustering by Coupled Trimers of Dimers [PDF]
Biophys J 96(2): 453-463 (2009), 2009 Receptors of bacterial chemotaxis form clusters at the cell poles, where clusters act as "antennas" to amplify small changes in ligand concentration. Interestingly, chemoreceptors cluster at multiple length scales. At the smallest scale, receptors form dimers, which assemble into stable timers of dimers.
arxiv +1 more source
Serotonergic modulators in Alzheimer's disease: a hope in the hopeless condition
Chemistry &Biodiversity, Accepted Article.Alzheimer disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Ali I. Al-Gareeb +5 more
wiley +1 more source
Localization and Upregulation of the Nasal Histamine H1 Receptor in Perennial Allergic Rhinitis
Mediators of Inflammation, 2012 In the present study, we have investigated the expression of histamine H1 receptor in human turbinates by RT-PCR, western blotting, and immunohistochemistry.
Hideaki Shirasaki +3 more
doaj +1 more source