Results 111 to 120 of about 114,014 (309)

IgE clonality and aggregation of insulin affect IgE-mediated activation of sensitized basophils

Journal of Allergy and Clinical Immunology: Global
Background: Skin prick testing and specific IgE determination do not discriminate between sensitization and clinically relevant insulin allergic reactions, whereas the basophil histamine release assay has proven useful in identifying clinically relevant ...
Steffen Christoffersen, MSc, Katrine Baumann, PhD, Anders Holm Millner, PhD, Henrik Toft-Hansen, PhD, Eva Johansson, PhD, Camilla Thorlaksen, PhD, Per Stahl Skov, PhD   +6 more
doaj   +1 more source

Honeycomb-like Structured Film Regulates Mediator Release from Non-Tumor Mast Cells

European Journal of Inflammation, 2014
We previously reported a honeycomb-like structured film (HCF) stimulates mast cell proliferation and multinucleated formation. In this study, we examined the role of HCF in regulating the release of mediators from cultured mast cells.
K. Sugimoto, H. Choi, M. Tanaka
doaj   +1 more source

Stabilizing histamine release in gut mast cells mitigates peripheral and central inflammation after stroke. [PDF]

J Neuroinflammation, 2023
Conesa MPB, Blixt FW, Peesh P, Khan R, Korf J, Lee J, Jagadeesan G, Andersohn A, Das TK, Tan C, Di Gesu C, Colpo GD, Moruno-Manchón JF, McCullough LD, Bryan R, Ganesh BP.   +15 more
europepmc   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Association of a SYK promoter polymorphism with SYK expression and IgE-mediated histamine release. [PDF]

Clin Exp Allergy, 2023
MacGlashan D, Gao L.
europepmc   +1 more source

Pharmacologic regulation of histamine release by the human recombinant histamine-releasing factor

Journal of Allergy and Clinical Immunology, 1999
The recently cloned human recombinant IgE-dependent histamine releasing factor (HrHRF) was initially thought to stimulate histamine release from human basophils from a subpopulation of allergic donors by interacting with the IgE molecules on the surface of these cells.
R, Bheekha-Escura, S R, Chance, J M, Langdon, D W, MacGlashan, S M, MacDonald   +4 more
openaire   +2 more sources

Component-Resolved in Vitro Diagnosis in Peach-Allergic Patients [PDF]

, 2009
BACKGROUND: The in vitro diagnosis of pollen-related food allergy presents low specifi city and reproducibility with many conventional extracts. This can be improved using natural purifi ed allergens, recombinant purifi ed allergens, or both.
Antepara, I., Barber, Domingo, Ferrer, M., Gamboa, P.M., Goikoetxea, M.J., Lombardero, M., Salcedo Duran, Gabriel, Sanz, M.L., Sánchez-Monge Laguna de Rins, Rosa   +8 more
core   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Progress in Allergy Signal Research on Mast Cells: The Role of Histamine in Immunological and Cardiovascular Disease and the Transporting System of Histamine in the Cell

Journal of Pharmacological Sciences, 2008
Since its discovery in 1910, histamine has been regarded as one of the most important biogenic amines in the medical and biological fields. This article summarizes the information about the role of histamine in allergic situations, atherosclerosis, and ...
Hiroshi Ohtsu
doaj   +1 more source

Evidence for histamine release in chronic inducible urticaria - A systematic review. [PDF]

Front Immunol, 2022
Kulthanan K, Church MK, Grekowitz EM, Hawro T, Kiefer LA, Munprom K, Nanchaipruek Y, Rujitharanawong C, Terhorst-Molawi D, Maurer M.   +9 more
europepmc   +1 more source