Evidence for a fisher‐designed solution to manta and devil ray bycatch in tuna fisheries
Abstract Bycatch in global tropical tuna purse seine fisheries represents a significant source of mortality for manta and devil rays (mobulids), which are globally threatened. Use of best handling and rapid release practices on purse seine vessels can substantially reduce mortality and improve vulnerability status for mobulids.
Melissa R. Cronin +12 more
wiley +1 more source
Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale. [PDF]
Mogi M +4 more
europepmc +1 more source
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami +2 more
wiley +1 more source
Vasicine Attenuates Allergic Asthma by Suppressing Mast Cell Degranulation and Th2 Inflammation via Modulation of the FcεRI/Lyn + Syk/MAPK Pathway. [PDF]
Qu L +9 more
europepmc +1 more source
Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review
ABSTRACT Background Hypertrophic scars and keloids, types of pathological scars, arise from dysregulated wound healing, marked by abnormal fibroblast activation and excessive extracellular matrix (ECM) deposition. Current treatments have high recurrence rates and side effects, necessitating targeted therapies. Exosomes, extracellular vesicles mediating
Mengke Wu +6 more
wiley +1 more source
Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]
Li G +13 more
europepmc +1 more source
Biochemical and Physiological Effects of Galanin in Health and Disease
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles +3 more
wiley +1 more source
T Cell/Mast Cell Crosstalk in the Skin of Patients Suffering From Immune-Mediated Diseases, Focusing on Chronic Spontaneous Urticaria. [PDF]
Toubi E, Mubariki R, Vadasz Z.
europepmc +1 more source
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu +5 more
wiley +1 more source
Repurposing antihistamines beyond allergy control: Emerging therapeutic potentials in liver cirrhosis. [PDF]
Huang HC.
europepmc +1 more source

