Results 261 to 270 of about 147,237 (374)
Narcolepsy and rapid eye movement sleep
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini +4 more
wiley +1 more source
Formononetin ameliorates mast cell-mediated allergic inflammation via inhibition of histamine release and production of pro-inflammatory cytokines. [PDF]
Exp Ther Med, 2017 Xu N, An J.
europepmc +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
Journal of Sleep Research, Volume 34, Issue 3, June 2025.Summary Although there have been promising findings for smartphone application (app)‐delivered cognitive behavioural therapy for insomnia (CBT‐I), previous trials have not screened participants rigorously for insomnia disorder and used therapist support.
Markus Jansson‐Fröjmark +1 more
wiley +1 more source
Autonomic block, cardiovascular depression and histamine release produced by polymyxin B in the cat [PDF]
, 1979 Chingmuh Lee +2 more
openalex +1 more source
MRI‐based surrogates of brain clearance in narcolepsy type 1
Journal of Sleep Research, EarlyView.Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese +6 more
wiley +1 more source
Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy
Journal of Sleep Research, EarlyView.ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash +5 more
wiley +1 more source
Infralimbic cortex activation and motivated arousal induce histamine release. [PDF]
Behav Pharmacol, 2015 Riveros ME, Forray MI, Torrealba F.
europepmc +1 more source
Neurogastroenterology &Motility, EarlyView.In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley +1 more source
Defective lymphatic vasculature in obesity
Obesity Reviews, EarlyView.Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley +1 more source