ABSTRACT Drought tolerance in crops often involves trade‐offs between water conservation, growth and reproduction. Understanding how water‐saving strategies are implemented at physiological and metabolic levels remains critical for improving crop performance under water‐limited conditions.
Ryosuke Mega +9 more
wiley +1 more source
High-level cefiderocol and ceftazidime/avibactam resistance in KPC-producing Klebsiella pneumoniae associated with mutations in KPC and the sensor histidine kinase EnvZ. [PDF]
Findlay J +3 more
europepmc +1 more source
Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu +6 more
wiley +1 more source
Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa. [PDF]
Fihn CA +15 more
europepmc +1 more source
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong +3 more
wiley +1 more source
The histidine kinase NahK regulates denitrification and nitric oxide accumulation through RsmA in <i>Pseudomonas aeruginosa</i>. [PDF]
Guercio D, Boon E.
europepmc +1 more source
PFAS properties and destruction methods: A focus on enzymatic degradation
Abstract Per‐ and polyfluoroalkyl substances (PFAS) are known as ‘forever’ chemicals and have lasting detrimental impact on the environment and living organisms. To understand PFAS molecules better, this review begins with an overview of PFAS definition, classifications and applications, and then provides a comprehensive summary and critical analysis ...
Guobin Liang, Hua Zhao
wiley +1 more source
Signaling by a bacterial phytochrome histidine kinase involves a conformational cascade reorganizing the dimeric photoreceptor. [PDF]
Burgie ES +7 more
europepmc +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source

