Results 71 to 80 of about 10,197 (233)

Evaluating VEGFR2 as a Target for Anti‐Tumour Therapy in Canine Melanoma

Veterinary and Comparative Oncology, Volume 24, Issue 1, Page 95-104, March 2026.
ABSTRACT Vascular endothelial growth factor receptor 2 (VEGFR2) is a key target for anti‐angiogenic oncotherapy, as inhibiting this receptor on tumour vasculature slows tumour development and enhances drug‐ and immune infiltration, improving therapy outcome.
Esther Hindriks, Wilhelmina Bergmann, Aitor Martínez Ruiz, Maurice M. J. M. Zandvliet, Alice J. A. M. Sijts, Femke Broere   +5 more
wiley   +1 more source

Effect of screening abdominal ultrasound examination on the decision to pursue advanced diagnostic tests and treatment in dogs with neurologic disease. [PDF]

, 2015
BackgroundAbdominal ultrasound examinations (AUS) are commonly performed before advanced neurodiagnostics to screen for diseases that might affect diagnostic plans and prognosis.ObjectivesDescribe the type and frequency of abnormalities found by AUS in ...
Blair, WH, Chen, RX, Sturges, BK, Taylor, SL, Tong, NM, Zwingenberger, AL   +5 more
core   +1 more source

Multifocal histiocytic sarcoma of the gastrointestinal tract

Indian Journal of Pathology and Microbiology, 2012
We report a rare case of extranodal histiocytic sarcoma with multifocal gastrointestinal tract involvement, which has not been documented in the literature so far.
Shirley Sundersingh, Urmila Majhi, Ramakrishnan Ayloor Seshadhri, Gnana Sagar Tenali   +3 more
doaj   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy, Raymond Barnhill, Boris C. Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony Gill, Jennelle C. Hodge, Joseph D Khoury, Katia Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Liang Zhiyong, Holger Moch, Rajendra Singh, Harshima Wijesinghe, Ian Cree, Dilani Lokuhetty   +29 more
wiley   +1 more source

The neural histogenetic origin of the oral granular cell tumor : an immunohistochemical evidence [PDF]

, 2011
Aims: Granular cell tumor (GCT) is a rare neoplasm that can appear in any site of the body, but most are located intraorally. Its histogenetic origin remains unclear. This report analyzes the immunoprofile of 15 cases of granular cell tumors, occurring
Campos, Marcia Sampaio, Cortes, Arthur Rodriguez Gonzalez, Júnior, Décio-dos-Santos-Pinto, Rejas, Roberto A. García, Sousa, Suzana COM de   +4 more
core   +1 more source

An unusual case of giant cell tumor of soft parts in an American Warmblood horse [PDF]

Open Veterinary Journal, 2019
Fine needle aspiration and tissue biopsy samples were taken from a subcutaneous mass in the cranial stifle region of a 10-year-old horse. Key cytologic features included: numerous mildly to moderately pleomorphic histiocytic cells admixed with ...
Kurt Zimmerman, Frederic Almy, Geoff Saunders, Mark Crisman, Leonardo Leonardi   +4 more
doaj   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Downregulation of Tumor Necrosis Factor Expression in the Human Mono-Mac-6 Cell Line [PDF]

, 1989
Mono-Mac-6 cells, but not U937 cells, can be Induced to rapidly express tumor necrosis factor (TNF) mRNA and protein when triggered with Ilpopolysaccharlde (LPS) at 1 pg/mI. Preincubatlon of the cells for 3 d with low amounts of LPS (10 ng/mI) results In
Blömer, Kathi, Haas, Jürgen G., Riethmüller, Gert, Thiel, Corinna, Weiss, Elisabeth H., Ziegler-Heitbrock, H. W. Löms   +5 more
core   +1 more source

Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature

Brain Sciences, 2022
Histiocytic sarcoma (HS) is a rare neoplasm composed of cells with immunohistochemical characteristics of mature histiocytes. It can be disseminated or localized and usually involves the skin, spleen, and gastrointestinal tract.
Eshagh Bahrami, Masoumeh Najafi, Amin Jahanbakhshi, Jaber Hatam, Saadat Molanaei, Patrizia Ciammella, Salvatore Cozzi   +6 more
doaj   +1 more source

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

American Journal of Hematology, Volume 101, Issue 1, Page 110-128, January 2026.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source