Case series of volar juvenile xanthogranuloma: Clinical observation of a peripheral rim of hyperkeratosis [PDF]
, 2014 Juvenile xanthogranuloma is a benign histiocytic tumor predominantly occurring in children as yellowish papules on the head and trunk. Presentations on the volar surfaces are rare and may cause diagnostic confusion with pyogenic granuloma, eccrine poroma
Amadi, Ugochukwu +7 more
core +1 more source
Journal of Medical Case Reports, 2019 Background Langerhans cell histiocytosis previously known as histiocytosis X is a rare disease of children and young adults with a very broad clinical spectrum. In children, its annual incidence is estimated between 0.2–0.5 per 100,000.
Salahoudine Idrissa +6 more
doaj +1 more source
Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate [PDF]
, 2010 Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor.
Agreda Vásquez, Gladys Patricia +4 more
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Paraneoplastic cerebellar degeneration associated with lymphoepithelial carcinoma of the tonsil [PDF]
, 2013 Background: Paraneoplastic cerebellar degeneration (PCD) is a classical tumor-associated, immune-mediated disease typically associated with gynecological malignancies, small-cell lung-cancer or lymphoma.
Hartmann, Sylvia +5 more
core +1 more source
Histiocitosis de células de Langerhans en el raquis infantil [PDF]
, 2006 Introducción: la Histiocitosis de células de Langerhans incluye un amplio espectro de enfermedades de etiología desconocida, observada preponderantemente en niños.
Fernández, Claudio A. +2 more
core
New somatic BRAF splicing mutation in Langerhans cell histiocytosis
Molecular Cancer, 2017 Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with constitutive activation of the MAPKinase RAS-RAF-MEK-ERK cell signaling pathway. We analyzed 9 LCH cases without BRAF V600 and MAP2K1 mutations by whole exome sequencing.
Sébastien Héritier +10 more
doaj +1 more source
Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature [PDF]
, 2019 Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment ...
Beck-Broichsitter, Benedicta +8 more
core +1 more source
Perifollicular Langerhans cell histiocytosis
Dermatology Online Journal, 2012 A 25-year-old man presented with a 13-year history of an erythematous, papular eruption of his face and trunk, which was treated in the past as acne and psoriasis with isotretinoin and methotrexate, respectively. Histopathologic examination demonstrated an infiltrate of Langerhans cells, which was consistent with Langerhans cell histiocytosis.
Mir, Adnan +3 more
openaire +4 more sources
Systemic findings of Langerhans cell histiocytosis in neonatal period
Revista de la Facultad de Ciencias de la Salud, 2011 We report an unusual case of mediastinal abcessed mass, with involvement of the lung, thymus and probably bone and hematopoietic system, in a newborn that was diagnosed with Langerhans cell histiocytosis.
Rosalba Días-Castro +6 more
doaj +2 more sources
Rare Tumors, 2011 We present a patient (50-year-old male) with coexisting Warthin tumor and involvement of two intraparotid lymph nodes by Langerhans cell histiocytosis associated with necrosis, eosinophilic abscesses and a granulomatous reaction.
Char Loo Tan +2 more
doaj +1 more source