Results 51 to 60 of about 38,208 (195)

Adult Langerhans cell histiocytosis with pulmonary and colorectoanal involvement: a case report

Journal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a rare systemic disease characterized by the abnormal overproduction of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage. It mainly affects – by order of
Mohamad Jihad Mansour, Elias Mokbel, Eddy Fares, Janah Maddah, Fadi Nasr   +4 more
doaj   +1 more source

Oral manifestation of Langerhans cell histiocytosis: a case report

BMC Oral Health, 2018
Bone necrosis of the jaw is a serious condition with a broad differential diagnosis of pathologies such as cutaneous histiocytosis, bone metastases or malignant tumours.
J. Luz, D. Zweifel, M. Hüllner, M. Bühler, M. Rücker, B. Stadlinger   +5 more
semanticscholar   +1 more source

Surveillance of Isolated Colonic Langerhans Cell Histiocytosis in an Adult: A Case Report

Journal of Investigative Medicine High Impact Case Reports, 2022
Langerhans cell histiocytosis (LCH) is a rare disorder involving the proliferation of myeloid-derived dendritic cells. It most commonly affects children aged less than 1 to 2 years old.
Sandhya Kolagatla MD, Joshua K. Jenkins MS, Joseph Elsoueidi MD, Nagabhishek Moka MD   +3 more
doaj   +1 more source

BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy.

Journal of Clinical Oncology, 2016
PURPOSE Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with a broad spectrum of clinical manifestations and outcomes in children.
S. Héritier, J. Emile, M. Barkaoui, C. Thomas, S. Fraitag, S. Boudjemaa, F. Renaud, A. Moreau, M. Peuchmaur, C. Chassagne‐Clément, F. Dijoud, V. Rigau, D. Moshous, A. Lambilliotte, F. Mazingue, K. Kébaili, Jean Miron, E. Jeziorski, G. Plat, N. Aladjidi, A. Ferster, H. Pacquement, C. Galambrun, L. Brugières, G. Leverger, L. Mansuy, C. Paillard, A. Deville, C. Armari‐Alla, A. Lutun, Marion Gillibert-Yvert, J. Stéphan, F. Cohen-Aubart, J. Haroche, I. Pellier, F. Millot, B. Lescoeur, V. Gandemer, C. Bodemer, R. Lacave, Z. Hélias‐Rodzewicz, V. Taly, F. Geissmann, J. Donadieu   +43 more
semanticscholar   +1 more source

Langerhans Cell Histiocytosis of the Tonsil

Balkan Medical Journal, 2022
Langerhans cell histiocytosis (LCH) is a rare disease that is characterized by clonal neoplastic proliferation of the dendritic Langerhans cells. LCH presents either with solitary or multiple organ involvement.1,2 The most commonly affected organs include the bones, skin, and pituitary gland; the hematopoietic system, lymph nodes, and lungs are rarely ...
Federica Cipolla , Martina Ragusa , Vittoria Bannò, Ignazio La Mantia , Claudio Andaloro   +4 more
openaire   +4 more sources

Morphological, immunohistochemical and molecular analysis of follicular dendritic cell sarcomas: L1CAM as a new diagnostic marker

Histopathology, EarlyView.
Pathohistological analysis of FDCS revealed a morphological spectrum and led to the identification of the adhesion molecule L1CAM as a novel diagnostic immunomarker for FDCS. Sequencing identified NFKBIA as the most frequently altered gene, of note, exclusively in cases with a predominant epithelioid cytomorphology.
Selina Schelbert, Katja Maurus, Sabine Roth, German Ott, Katrin S Kurz, Carolin Mogler, Barbara Wollenberg, John Linde, Alberto Zamo, Ioannis Anagnostopoulos, Susanne Gramlich, Andreas Rosenwald, Elena Gerhard‐Hartmann   +12 more
wiley   +1 more source

Novel report of an osteogenic tumor in a late Jurassic Mamenchisaurid from Thailand

Journal of Anatomy, EarlyView.
Here we describe a pathology in an ulna of a Late Jurassic mamenchisaurid from Thailand. We use anatomical descriptions, CT scanning, and bone histology to identify the pathology as an osteogenic tumor. Abstract Here we report on an osseous abnormality and multiple fractures in an ulna of a subadult basal Eusauropod (Mamenchisauridae) from the Late ...
Siripat Kaikaew, Suravech Suteethorn, Anusuya Chinsamy   +2 more
wiley   +1 more source

Otic Langerhans' Cell Histiocytosis in an Adult: A Case Report and Review of the Literature

Case Reports in Otolaryngology, 2013
Objective. To present a case of otic Langerhans' cell histiocytosis in an adult. Also included the diagnosis and management of the condition and a review of the relevant literature. Case Report.
Anil Gungadeen, Peter Kullar, Philip Yates   +2 more
doaj   +1 more source

RAF/MEK/extracellular signal–related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

Journal of Experimental Medicine, 2018
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia characterized by granulomatous lesions containing pathological CD207+ dendritic cells (DCs) with constitutively activated mitogen-activated protein kinase (MAPK) pathway signaling ...
Brandon Hogstad, M. Berres, Rikhia Chakraborty, Jun Tang, Camille Bigenwald, Madhavika N. Serasinghe, Karen Phaik Har Lim, Howard Lin, T. Man, R. Remark, Samantha Baxter, V. Kana, Stefan Jordan, Zoi Karoulia, Wing-hong Kwan, M. Leboeuf, E. Brandt, Hélène Salmon, K. McClain, Poulikos I. Poulikakos, J. Chipuk, W. Mulder, C. Allen, M. Merad   +23 more
semanticscholar   +1 more source

Pulmonary langerhans cell histiocytosis [PDF]

Orphanet Journal of Rare Diseases, 2012
AbstractPulmonary Langerhans Cell Histiocytosis (PLCH) is a relatively uncommon lung disease that generally, but not invariably, occurs in cigarette smokers. The pathologic hallmark of PLCH is the accumulation of Langerhans and other inflammatory cells in small airways, resulting in the formation of nodular inflammatory lesions.
Harpreet S. Suri, Eunhee S. Yi, Robert Vassallo, G.S. Nowakowski   +3 more
openaire   +4 more sources