Late-Onset Langerhans Cell Histiocytosis Presenting with Seizures and Bilateral Temporal Involvement
Langerhans cell histiocytosis is known as a rare childhood disease. In this case, we wanted to share our patient’s experience whose first symptom was an epileptic seizure, which attracted attention at an advanced age and revealed bilateral temporal lobe ...
Özge Öcek, Hasan Kuş, Pınar Ortan
doaj +1 more source
Multisystem Langerhans' cell histiocytosis (Hand-Schüller-Christian disease) in an adult: a case report and review of the literature [PDF]
Langerhans' cell histiocytosis (LCH) is a rare and enigmatic clonal disorder that affects mainly children. It is characterized by single or multiple granulomatous mass lesions composed of cells with the Langerhans' cell phenotype.
Jaques, B. +3 more
core
Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples [PDF]
This review article deals with the analysis and the detection of the morphological features associated with somatic mutations, mostly BRAF(V600E) mutation, on both cytological and histological samples of carcinomas.
Abildgaard +112 more
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We evaluated the diagnostic utility of GPNMB immunohistochemistry in LAM. GPNMB showed strong expression in LAM cells, while the differential diagnostic mimics showed no or only low expression. Based on its 100% sensitivity and specificity in our cohort, GPNMB is a highly reliable immunohistochemical marker for the diagnosis of LAM.
Fatime Szalai +6 more
wiley +1 more source
High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues. [PDF]
International audienceBACKGROUND: Langerhans cell (LC) sarcoma (LCS) is a high-grade neoplasm with overtly malignant cytologic features and an LC phenotype.
A Kanik +38 more
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ABSTRACT Ruptured hydatid cyst should be considered when encountering spontaneous pneumothorax and pneumomediastinum, especially in young patients in regions with high prevalence of hydatid cyst. Awareness of atypical signs ensures instant diagnosis, guiding appropriate surgical and medical treatment to prevent serious complications.
Farzaneh Akbari +5 more
wiley +1 more source
CASE OF GUILLAIN-BARRE´ SYNDROME IN A PATIENT WITH PULMONARY LANGERHANS CELL HYSTIOCYTOSIS
Langerhans cell histiocytosis is a rare disease characterized by various clinical patterns: from isolated lung lesions to severe involvement of other organs.
E. V. Efremova +5 more
doaj +1 more source
Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate [PDF]
Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor.
Agreda Vásquez, Gladys Patricia +4 more
core
Histiocytosis x: Recurrent isolated mandibular lesion (case report) [PDF]
Histiocytosis X usually affects children and adolescents. In our case, a 54-year-old woman was admitted to hospital for evaluating and treatment of an isolated, painless swelling of the left side of the mandible.
Arizanović Marko +3 more
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Langerhans cell histiocytosis (histiocytosis X) [PDF]
Summary There has been a renewed interest in Langerhans cell histiocytosis in recent years due both to advances in basic research and to improvements in diagnostic and treatment approaches. In this article, we review the various aspects of the disease and the potential implications of these recent scientific researches for our ...
openaire +3 more sources

