Results 1 to 10 of about 3,233 (128)

Sinus Histiocytosis with Massive Lymphadenopathy [PDF]

Ca-A Cancer Journal for Clinicians, 1980
A 22-month-old child presented with massive cervical adenopathy accompanied by a retropharyngeal mass that caused stridor and dysphagia. Biopsy from both sides was consistent with sinus histiocytosis with massive lymphadenopathy (SHML). SHML is an unusual benign lesion that characteristically presents with painless, massive cervical adenopathy ...
David R Kelly
exaly   +3 more sources

Clinicopathological Features, Treatment Response, and Outcome of Rosai‐Dorfman Disease in Two Children [PDF]

Clin Case Rep
ABSTRACT Rosai‐Dorfman disease is a rare non‐Langerhans cell histiocytic disorder. It is common in male children and young adults of African descent. It is classified into sporadic and familial types. The most common clinical presentation is massive bilateral cervical lymphadenopathy associated with constitutional symptoms. Histiocytic emperipolesis is
Evele G, Francine K.
europepmc   +2 more sources

Characteristics of histiocytic neoplasms presenting as breast masses. [PDF]

Br J Haematol
British Journal of Haematology, Volume 208, Issue 1, Page 358-362, January 2026.
Vougiouklakis T, Rosenblum MK, Cannavo M, Feigin K, Rosenberg AE, Wittlin F, Mahajan S, Brogi E, Arcila ME, Wen HY, Diamond EL.   +10 more
europepmc   +2 more sources

Erdheim-Chester disease associated with myeloid neoplasm: Clinical features, molecular landscape, and treatment outcomes. [PDF]

Hemasphere
Abstract Erdheim‐Chester disease (ECD) is frequently associated with clonal hematopoiesis and myeloid neoplasms (MN), but clinical phenotype and response to kinase inhibitors (KI) in this setting remain unclear. We analyzed 67 patients with ECD associated with MN (ECD‐MN) from a French national cohort and assessed ECD treatment response, MN progression,
Le Pogam A, Papo M, Hirsch P, Cohen-Aubart F, Emile JF, Delhommeau F, Duffau P, Razanamahery J, Nguyen-Khac F, Nunes Gomes C, Triboulet F, de La Rochefoucauld J, McAvoy C, Lazaro E, Hage-Sleiman M, Roos-Weil D, Chasset F, Jachiet V, Mekinian A, Fain O, Amoura Z, Hadjadj J, Haroche J.   +22 more
europepmc   +2 more sources

Region-Based Segmentation of Lymph Node Metastases in Whole-Slide Images of Colorectal Cancer: A Pilot Clinical Study. [PDF]

Cancer Med
ABSTRACT Background Digital technologies and artificial intelligence (AI) are transforming medical diagnostics, particularly in pathology. This study presented a two‐stage computer vision model designed to detect colorectal cancer metastases in whole slide images (WSIs) of lymph nodes.
Fayzullin A, Savelov N, Balkivskiy A, Ivanova E, Timakova A, Funtikov V, Shelomentseva E, Panchenko N, Spiridonov I, Korkonishko I, Makhina M, Kutuzova E, Meretukov D, Kretova N, Demura T, Timashev P, Parchiev R.   +16 more
europepmc   +2 more sources

Sinus Histiocytosis with Massive Lymphadenopathy [PDF]

Leukemia & Lymphoma, 1992
To date, the morphological aspects of sinus histiocytosis with massive lymphadenopathy (SHML) have been fully described. The disease is characterized by an enlargement of lymph nodes in which the sinuses are dilated and infiltrated by histiocytes, often phagocytosing lymphocytes.
SACCHI, Stefano, ARTUSI, Tullio, TORELLI, Umberto, EMILIA, Giovanni   +3 more
openaire   +4 more sources

Sinus Histiocytosis with Massive Lymphadenopathy

Indian Journal of Otolaryngology and Head and Neck Surgery, 2006
Sinus Histiocytosis with Massive Lymphadenopathy is a very rare condition often presenting as neck swelling of unknown etiology. The disease involves extranodal sites in 20-30 percent of cases and histologically characterized by emperiopolesis, non-cohesive and non-epitheloid histocytes with abundant eosinphilic cytoplasm.
, Samiullah, , Hidayatullah, Nisar H, Dar, Faisal, Haque, S A, Hasan   +4 more
openaire   +3 more sources

Next‐Generation Paleopathology: Using Commercial AI in Bioarchaeological Diagnosis

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Artificial intelligence encompasses computational systems capable of performing cognitive functions such as learning, reasoning, and problem‐solving. Within this domain, generative AI and large language models such as ChatGPT, Gemini, and Copilot have shown significant potential in clinical diagnostics.
Jessica Mongillo, Giulia Vescovo, Giulia Manzo, Nicoletta Zedda, Barbara Bramanti   +4 more
wiley   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

The Journal of Pathology, EarlyView.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +1 more source

Case series: Kikuchi‐Fujimoto disease with diagnostic overlap

Rheumatology &Autoimmunity, EarlyView.
Kikuchi‐Fujimoto disease (KFD) is a rare, self‐limiting necrotizing lymphadenitis that poses significant diagnostic challenges due to its overlap with tuberculosis, systemic lupus erythematosus (SLE), and malignancy. We present four cases highlighting distinct diagnostic complexities: KFD mimicking tuberculosis with concomitant latent TB infection and ...
Ecem Kalemoglu, Ming Zheng, Danny Arias, Andreina M. Paulino, Aisha Niaz, James Devlin, Valentin Marian   +6 more
wiley   +1 more source