Results 1 to 10 of about 5,266 (225)

Sinus Histiocytosis with Massive Lymphadenopathy [PDF]

Ca-A Cancer Journal for Clinicians, 1980
A 22-month-old child presented with massive cervical adenopathy accompanied by a retropharyngeal mass that caused stridor and dysphagia. Biopsy from both sides was consistent with sinus histiocytosis with massive lymphadenopathy (SHML). SHML is an unusual benign lesion that characteristically presents with painless, massive cervical adenopathy ...
David R Kelly, William Crist
exaly   +3 more sources

Clinicopathological Features, Treatment Response, and Outcome of Rosai‐Dorfman Disease in Two Children [PDF]

Clin Case Rep
ABSTRACT Rosai‐Dorfman disease is a rare non‐Langerhans cell histiocytic disorder. It is common in male children and young adults of African descent. It is classified into sporadic and familial types. The most common clinical presentation is massive bilateral cervical lymphadenopathy associated with constitutional symptoms. Histiocytic emperipolesis is
Evele G, Francine K.
europepmc   +2 more sources

Characteristics of histiocytic neoplasms presenting as breast masses. [PDF]

Br J Haematol
British Journal of Haematology, Volume 208, Issue 1, Page 358-362, January 2026.
Vougiouklakis T, Rosenblum MK, Cannavo M, Feigin K, Rosenberg AE, Wittlin F, Mahajan S, Brogi E, Arcila ME, Wen HY, Diamond EL.   +10 more
europepmc   +2 more sources

Asymptomatic flow of Rosai-Dorfman disease [PDF]

Vojnosanitetski Pregled, 2014
Introduction. Sinus histiocytosis with massive lymphadenopathy is a rare benign self-limiting disease of unknown etiology. The salivary gland involvement, indicating the extranodal character of the disease, often presents a diagnostic dilemma ...
Petrović Dragan, Mihailović Dragan, Petrović Slađana, Živković Nikola, Mijovićć Žaklina, Bjelaković Bojko, Kostić Miloš, Kesić Ljiljana, Stanković Ana, Petrović Milica, Vučković Ivica   +10 more
doaj   +3 more sources

Erdheim-Chester disease associated with myeloid neoplasm: Clinical features, molecular landscape, and treatment outcomes. [PDF]

Hemasphere
Abstract Erdheim‐Chester disease (ECD) is frequently associated with clonal hematopoiesis and myeloid neoplasms (MN), but clinical phenotype and response to kinase inhibitors (KI) in this setting remain unclear. We analyzed 67 patients with ECD associated with MN (ECD‐MN) from a French national cohort and assessed ECD treatment response, MN progression,
Le Pogam A, Papo M, Hirsch P, Cohen-Aubart F, Emile JF, Delhommeau F, Duffau P, Razanamahery J, Nguyen-Khac F, Nunes Gomes C, Triboulet F, de La Rochefoucauld J, McAvoy C, Lazaro E, Hage-Sleiman M, Roos-Weil D, Chasset F, Jachiet V, Mekinian A, Fain O, Amoura Z, Hadjadj J, Haroche J.   +22 more
europepmc   +2 more sources

Region-Based Segmentation of Lymph Node Metastases in Whole-Slide Images of Colorectal Cancer: A Pilot Clinical Study. [PDF]

Cancer Med
ABSTRACT Background Digital technologies and artificial intelligence (AI) are transforming medical diagnostics, particularly in pathology. This study presented a two‐stage computer vision model designed to detect colorectal cancer metastases in whole slide images (WSIs) of lymph nodes.
Fayzullin A, Savelov N, Balkivskiy A, Ivanova E, Timakova A, Funtikov V, Shelomentseva E, Panchenko N, Spiridonov I, Korkonishko I, Makhina M, Kutuzova E, Meretukov D, Kretova N, Demura T, Timashev P, Parchiev R.   +16 more
europepmc   +2 more sources

Tumoral Stage of Mycosis Fungoides, Misdiagnosed With Wells Syndrome and Langerhans Cell Histiocytosis Histologically: A Challenging Case and Review of the Literature. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Mycosis fungoides (MF) is a type of cutaneous T‐cell lymphoma (CTCL) with slow progression, usually presenting with patches and plaques. The infiltration of histiocytes and eosinophils in skin cancers can mask the underlying condition, posing a diagnostic challenge.
Vahabi SM, Montazeri S, Pourgholi E, Bahramian S, Ghanadan A, Hesari KK, Etesami I.   +6 more
europepmc   +2 more sources

The Clinicopathologic Spectrum of Rosai-Dorfman-Destombes Disease in Adults: An Analysis of 16 Cases. [PDF]

Eur J Haematol
ABSTRACT Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytic proliferation with protean clinical manifestations, resulting from the accumulation of activated histiocytes within nodal and extra‐nodal tissues. The diagnosis can be missed, particularly when biopsies are obtained from extra‐nodal sites, where histological features may be less ...
Trinder M, Pryma C, Leung E, Slack GW, Farinha P, Young S, Ozkaya N, Carruthers M, Chen LYC.   +8 more
europepmc   +2 more sources

ALK-positive histiocytosis involving the cavernous sinus: A deceptive radiologic mimic of meningioma

Radiology Case Reports, 2023
Anaplastic lymphoma kinase (ALK)-positive histiocytosis is an uncommon condition, recently considered a separate condition from other histiocytosis by WHO 5th edition. It can involve intracranial structures.
Mohammadreza Alizadeh, MD, Aishwarya Ravindran, MD, Rati Chkheidze, MD, Gaurav Goyal, MD, Mahdie Hosseini, MD, Parnian Shobeiri, MD, Arezoo Shafieioun, MD, Mohammad Khalafi, MD, Ramin Shahidi, Houman Sotoudeh, MD, Aparna Singhal, MD   +10 more
doaj   +1 more source

Patient with Rosai-Dorfman-Destombes disease: 18F-FDG-PET/CT scan as a diagnostic tool

Acta Médica Peruana, 2023
Rosai-Dorfman-Destombes disease (RDD) is a rare non-Langerhans cell histiocytosis, with sinus involvement and massive lymphadenopathy. RDD is usually self-limited; it can appear alone or related to other diseases. We present a 9-year-old male with biopsy
Luis C. Araujo Cachay
doaj   +1 more source