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Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease is an unusual, benign, selflimited condition of unknown etiology which generally presents as massive bilateral cervical lymphadenopathy in children.
R Tangsathitporn, A Nitiruangjarus
doaj
Management of a patient with Rosai–Dorfman syndrome and large adrenal pheochromocytoma
Sinus histiocytosis with massive lymphadenopathy that known as Rosai Dorfman syndrome (RDS)is a rare histiocytic disease which includes benign lymph nodes (LN) enlargement with extra-lymphatic soft tissue involvement.
Taha O Mahwi, Najmaddin Khoshnaw
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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a rare benign disease of unknown etiology presenting with massive lymphadenopathy. These cases can often be misdiagnosed as lymphoma.
Kushwaha Rashmi +2 more
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New cases expand the genotype, phenotype and therapeutic landscape of H syndrome
British Journal of Haematology, Volume 208, Issue 1, Page 363-366, January 2026.
Clément Triaille +10 more
wiley +1 more source
Pediatric Allergy and Immunology, Volume 37, Issue 1, January 2026.
Clément Triaille +2 more
wiley +1 more source
Extranodal manifestation of Rosai-Dorfman disease with bilateral ocular involvement
Rosai-Dorfman disease, that is, sinus histiocytosis with massive lymphadenopathy is a benign systemic proliferative disorder of histiocytes. The typical clinical presentation of the disease includes bilateral painless massive lymphadenopathy, fever and ...
Chayanika Kala +2 more
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Rosai–Dorfman disease as chronic bilateral granulomatous anterior uveitis: A case report
Rosai–Dorfman disease is a rare non-Langerhans cell histiocytosis disorder, also known as sinus histiocytosis, with massive lymphadenopathy. Rosai–Dorfman disease is classified into nodal and extranodal diseases.
Yaninsiri Ngathaweesuk +1 more
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The author describes a case of massive lynphadenopathy, fever, astenia and sweating, with 3 weeks evolution. The patient was investigated in a health unit in Sapiranga – RS, Brazil, where he diagnosed with sinus histiocytosis (Rosai-Dorfman disease). After initial treatment in the health unit, the patient was transferred to a reference service.
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