Megakaryocyte emperipolesis: a new frontier in cell-in-cell interaction
Histology of bone marrow routinely identifies megakaryocytes that enclose neutrophils and other hematopoietic cells, a phenomenon termed emperipolesis.
Pierre Cunin, Peter A. Nigrovic
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Primary Cutaneous Rosai-Dorfman Disease With Typical Immunophenotype But Lacking Emperipolesis: A Case Report [PDF]
Background: Cutaneous Rosai–Dorfman disease (CRDD) is a rare extranodal histiocytosis that can mimic other dermatoses, particularly when hallmark emperipolesis is absent.
Lina Al-Soufi +5 more
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Genetic deletion of P-selectin prevents fibrosis development by inhibiting the neutrophil megakaryocyte emperipolesis in the Gata1low mouse model for myelofibrosis [PDF]
Myelofibrosis (MF) is a rare chronic hematological disorder, within the family of myeloproliferative neoplasms. The MF patients present clinical abnormalities such as anemia, and thrombosis, as well as alterations in the bone marrow (BM ...
Francesca Arciprete +9 more
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Clinicopathological Features, Treatment Response, and Outcome of Rosai‐Dorfman Disease in Two Children [PDF]
Rosai‐Dorfman disease is a rare non‐Langerhans cell histiocytic disorder. It is common in male children and young adults of African descent. It is classified into sporadic and familial types.
George Evele +2 more
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Case Report: ALK-positive histiocytosis presenting as an adrenal mass: a diagnostic trap due to unusual morphology [PDF]
BackgroundThe differential diagnosis of an adrenal mass is critical for clinical management. We report a case that expanded the spectrum of a rare disease and present a novel diagnostic trap for both pathologists and clinicians.MethodsHistopathological ...
Wenjing Ma +4 more
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Acute mucocutaneous syndrome and hemophagocytic lymphohistiocytosis following COVID-19 with prominent emperipolesis [PDF]
Kylie S. Andonian, BS +1 more
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Isolated intracranial Rosai-Dorfman disease in an adult man: Report of a rare case [PDF]
Background: Isolated intracranial Rosai-Dorfman disease (RDD) is an extremely rare, idiopathic histo-proliferative disorder. RDD is associated with the proliferation of histiocytes and emperipolesis.
Somaye Rezaei +5 more
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Emperipolesis – A Review [PDF]
Emperipolesis is an uncommon biological process, in which a cell penetrates another living cell. Unlike in phagocytosis where the engulfed cell is killed by lysosomal enzymes of the macrophage, the cell exists as viable cell within another in ...
Varun Rastogi +4 more
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Cerebral CD1a positive Rosai–Dorfman disease with coexistent granulomatous angiitis: A case report
Rosai–Dorfman disease (RDD) is a nonneoplastic histiocytic proliferation. RDD is CD1a negative as opposed to Langerhans cell histiocytosis (LCH). The lesion was positive for CD1a immunohistochemistry in our RDD patient, suggesting an overlap with LCH. In
Sweety Vijay Shinde, Asha Sharad Shenoy
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Rosai–Dorfman disease (RDD) is a rare disorder characterized by the proliferation of histiocytes in lymph nodes. It can occur anywhere in the body but commonly involves the cervical area of the neck.
Erinie Mekheal +6 more
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