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A rare case of oral multisystem Langerhans cell histiocytosis [PDF]

Journal of Clinical and Experimental Dentistry, 2017
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by high proliferation of Langerhans dendritic cells. LCH is a solitary or multifocal disease that primarily involves bone tissue and often affects children and young men. A 29 years-old
Facciolo, Maria Teresa, Gaglioti, Domenico, Gallenzi, Patrizia, Patini, Romeo, Riva, Francesco   +4 more
core   +2 more sources

International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults

Blood, 2022
Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary (smoking-associated), or multisystem disease.
G. Goyal, A. Tazi, R. Go, K. Rech, J. Picarsic, R. Vassallo, Jason R. Young, C. Cox, J. V. van Laar, M. Hermiston, Xin-xin Cao, P. Makras, G. Kaltsas, J. Haroche, M. Collin, K. McClain, E. Diamond, M. Girschikofsky   +17 more
semanticscholar   +1 more source

ALK+ histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition.

Blood, 2021
ALK-related histiocytosis (formerly ALK-positive histiocytosis) is a rare subtype of histiocytic neoplasm first described in 2008 in three infants with multisystemic disease involving the liver and hematopoietic system.
P. Kemps, J. Picarsic, B. Durham, Z. Hélias‐Rodzewicz, L. Hiemcke-Jiwa, C. van den Bos, M. D. van de Wetering, C. V. van Noesel, J. V. van Laar, R. Verdijk, U. Flucke, P. Hogendoorn, F. J. S. H. Woei‐A‐Jin, R. Sciot, A. Beilken, F. Feuerhake, M. Ebinger, R. Möhle, F. Fend, A. Bornemann, V. Wiegering, K. Ernestus, T. Méry, O. Gryniewicz‐Kwiatkowska, B. Dembowska-Bagińska, D. Evseev, V. Potapenko, V. Baykov, S. Gaspari, S. Rossi, M. Gessi, G. Tamburrini, S. Héritier, J. Donadieu, Jacinthe Bonneau-Lagacherie, Claire Lamaison, L. Farnault, S. Fraitag, M. Jullie, J. Haroche, M. Collin, J. Allotey, Majid Madni, K. Turner, S. Picton, P. Barbaro, A. Poulin, Ingrid S Tam, D. El Demellawy, Brianna Empringham, J. Whitlock, A. Raghunathan, Amy A. Swanson, M. Suchi, Jon Brandt, N. Yaseen, J. Weinstein, I. Eldem, B. Sisk, V. Sridhar, Mandy M Atkinson, Lucas R. Massoth, J. Hornick, S. Alexandrescu, K. Yeo, K. Petrova-Drus, Stephen Z Peeke, Laura Muñoz-Arcos, D. Leino, D. Grier, R. Lorsbach, Somak Roy, Ashish R. Kumar, Shipra Garg, Nishant Tiwari, K. Schafernak, Michael M. Henry, A. V. van Halteren, O. Abla, E. Diamond, J. Emile   +80 more
semanticscholar   +1 more source

Histiocytosis and the nervous system: from diagnosis to targeted therapies

Neuro-Oncology, 2021
Histiocytoses are heterogeneous hematopoietic diseases characterized by the accumulation of CD68(+) cells with various admixed inflammatory infiltrates.
F. Cohen Aubart, A. Idbaih, J. Emile, Z. Amoura, O. Abdel-Wahab, B. Durham, J. Haroche, E. Diamond   +7 more
semanticscholar   +1 more source

Langerhans cell histiocytosis: Version 2021

Hematological Oncology, 2021
Children with Langerhnans cell histiocytosis (LCH) develop granulomatous lesions with characteristic clonal CD207+ dendritic cells that can arise as single lesions or life‐threatening disseminated disease. Despite the wide range of clinical presentations,
N. Gulati, C. Allen
semanticscholar   +1 more source

Langerhans cell histiocytosis

Indian Journal of Medical Research, 2018
Langerhans cell histiocytosis (LCH) formerly known as pulmonary eosinophilic granuloma is currently regarded by the World Health Organization as a clonal neoplastic proliferation of histiocytes.
Anil S Menon, Manish Kumar
openaire   +4 more sources

Langerhans Cell histiocytosis.

Blood, 2020
Langerhans Cell Histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction.
C. Rodríguez-Galindo, C. Allen
semanticscholar   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review.

Frontiers in Medicine, 2021
Immune thrombocytopenia (ITP) is a rare autoimmune-mediated condition characterized by isolated thrombocytopenia (<100 G/L) after exclusion of other causes.
Jerome Razanamahery, Sebastien Humbert, Jean-Francois Emile, Fleur Cohen-Aubart, Jean Fontan, Philippe Maksud, Sylvain Audia, Julien Haroche   +7 more
doaj   +1 more source

Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study

Orphanet Journal of Rare Diseases, 2020
Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe presentations are observed. Methods Among 1482 children (
Solenne Le Louet, Mohamed-Aziz Barkaoui, Jean Miron, Claire Galambrun, Nathalie Aladjidi, Pascal Chastagner, Kamila Kebaili, Corinne Armari-Alla, Anne Lambilliotte, Julien Lejeune, Despina Moshous, Valeria Della Valle, Chiara Sileo, Hubert Ducou Le Pointe, Jean-François Chateil, Sylvain Renolleau, Jean-Eudes Piloquet, Aurelie Portefaix, Ralph Epaud, Raphaël Chiron, Emmanuelle Bugnet, Gwenaël Lorillon, Abdelatif Tazi, Jean-François Emile, Jean Donadieu, Sébastien Héritier   +25 more
doaj   +1 more source