Results 11 to 20 of about 21,961 (244)

HISTIOCYTOSIS X

Archives of Pediatrics & Adolescent Medicine, 1971
1. The clinical, histological and radiological findings in 129 cases of histiocytosis X have been reviewed and the natural history of the disease is discussed. 2. Certain clinical and histological factors emerge as having prognostic significance.
C. Cheyne
core   +5 more sources

Histiocytosis X

Annals of African Medicine, 2009
Histiocytosis X (Langerhan’s cell granulomatosis) is a disease of unknown aetiology, but viral origin has been implicated.1 It is a clinicopathologic entitycharacterized by proliferation of Langerhan’s cell (which are not primarily phagocytic) in an ...
Yau, L.Z., Mohammed, A, Ahmed, SA, Samaila, M.O.A., Chom, ND, Mohammed, A., Samaila, M. O. A., Chom, N.D., Yau, LZ, Ahmed, S.A., Samaila, MOA   +10 more
core   +6 more sources

Establishment of MOS-SF36 percentile ranks in the general youth French population

BMC Psychology, 2022
Background The SF-36 is a generic quality of life questionnaire, massively translated and widely used to obtain physical and mental health status. However, validation work in the French language was carried out over a generation ago.
Arthur Trognon, Emilie Tinti, Blandine Beaupain, Jean Donadieu, Michel Musiol   +4 more
doaj   +1 more source

Efficacy of MAPK inhibitors in children with neurodegenerative Langerhans cell histiocytosis: Results from the European Consortium for Histiocytosis. [PDF]

Hemasphere
Abstract Neurodegenerative Langerhans cell histiocytosis (ND‐LCH) is a severe and debilitating complication of LCH with no effective treatment. In this study, we assessed the efficacy of MAPK inhibitors (MAPKi) in a large cohort of children with ND‐LCH. We included pediatric patients with ND‐LCH who received MAPKi between 2013 and 2025.
Pegoraro F, Chalard F, Evseev D, Barkaoui M, Le Louet S, Thalhammer J, Aladjidi N, Salmon A, Marec-Berard P, Gaspari S, De Fusco C, Trambusti I, Verrico A, Raciborska A, Svojgr K, Křenová Z, Slater O, Millen G, Ben Arush M, Ashkenazi Lustig D, Von Bahr Greenwood T, Hutter C, Astigarraga I, López-Duarte M, Valero-Arrese L, Ortega Acosta MJ, van den Bos C, Naeije L, Martin-Munoz D, Perrone A, Mortilla M, Felician O, Idbaih A, Héritier S, Nanduri V, Minkov M, Henter JI, Sieni E, Donadieu J.   +38 more
europepmc   +2 more sources

Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis

Cell Communication and Signaling, 2022
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK
Xue-min Gao, Jian Li, Xin-xin Cao
doaj   +1 more source

ALK-positive histiocytosis involving the cavernous sinus: A deceptive radiologic mimic of meningioma

Radiology Case Reports, 2023
Anaplastic lymphoma kinase (ALK)-positive histiocytosis is an uncommon condition, recently considered a separate condition from other histiocytosis by WHO 5th edition. It can involve intracranial structures.
Mohammadreza Alizadeh, MD, Aishwarya Ravindran, MD, Rati Chkheidze, MD, Gaurav Goyal, MD, Mahdie Hosseini, MD, Parnian Shobeiri, MD, Arezoo Shafieioun, MD, Mohammad Khalafi, MD, Ramin Shahidi, Houman Sotoudeh, MD, Aparna Singhal, MD   +10 more
doaj   +1 more source

Case Report: ALK-Positive Histiocytosis With KIF5B-ALK Fusion in Cerebrum-Disseminated Lesions in a Child

Frontiers in Oncology, 2022
BackgroundAnaplastic lymphoma kinase (ALK)-positive histiocytosis is a rare type of histiocytosis that could affect multiple systems in children and adults.
Yi Guo, Yi Guo, Hai-bo Qu, Hai-bo Qu, Gang Ning, Gang Ning, Feng-lin Jia, Feng-lin Jia, Hong Liu, Xin-mao Ma, Xin-mao Ma, Yi Liao, Yi Liao   +12 more
doaj   +1 more source

Late-Onset Langerhans Cell Histiocytosis Presenting with Seizures and Bilateral Temporal Involvement

, 2022
Langerhans cell histiocytosis is known as a rare childhood disease. In this case, we wanted to share our patient’s experience whose first symptom was an epileptic seizure, which attracted attention at an advanced age and revealed bilateral temporal lobe ...
Özge Öcek, Hasan Kuş, Pınar Ortan
core   +1 more source

Langerhans cell histiocytosis developing acute lymphoblastic leukemia

SAGE Open Medical Case Reports, 2022
The sequential occurrence of Langerhans cell histiocytosis and acute leukemia in only one individual has been reported previously; however, it is rarely observed that Langerhans cell histiocytosis can transform into acute lymphoblastic leukemia, and the ...
JinFang Zhang, Sa Zong, Bing Liao
doaj   +1 more source

ERDHEIM-Chester Disease: Two Fatal Cases With Unusual Presentations. [PDF]

Clin Case Rep
Fluorodeoxyglucose positron emission tomography‐computed tomography (FDG PET‐CT) demonstrated markedly increased metabolic activity in serosal surfaces including pericardium, pleura, and renal fascia, as well as diffuse uptake along vascular walls, particularly the entire aorta.
Daniel Andres RV, Álvarez Payares José C, Juliana MP.   +2 more
europepmc   +2 more sources