Results 51 to 60 of about 5,197,064 (280)
ABSTRACT Langerhans cell sarcoma (LCS) is a rare neoplastic proliferation of Langerhans cell with aggressive clinical behavior and involves multiple organ systems, including the skin. LCS is characterized by marked cytologic atypia, frequent mitoses including atypical ones, and expression of CD1a, S100, and langerin (CD207).
Randa Obid+8 more
wiley +1 more source
Sex‐dimorphic gene regulation in murine macrophages across niches
In this study, we perform a meta‐analysis of new and publicly available RNA‐seq datasets from male and female mouse macrophages across eight niches to identify conserved sex‐dimorphic gene expression patterns. We found that three sex chromosome‐linked genes are always differentially expressed between males and females: Ddx3y, Eif2s3y and Xist. However,
Cassandra J McGill+4 more
wiley +1 more source
Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature [PDF]
Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment ...
Beck-Broichsitter, Benedicta+8 more
core +1 more source
Abstract Background Cancer is the leading cause of death in children aged 1–14 and the second in 15‐19‐year‐old adolescents in Spain. The Paediatric Population‐Based Cancer Registry of the Community of Madrid was created to monitor its incidence and survival.
Raquel López‐González+5 more
wiley +1 more source
Diagnosis of Rosai-Dorfman Disease by Fine Needle Aspiration Cytology in a Case with Cervical Lymphadenopathy and Nasal Mass [PDF]
We report a case of Rosai-Dorfman Disease, a rare non neoplastic proliferative disorder of the cells of macrophage-histiocyte family, in a case with cervical lymphadenopathy and nasal mass diagnosed by fine needle aspiration ...
Jena, M
core +1 more source
Changes in multi‐gene cancer panels for children: A 4‐year retrospective review
Abstract The multi‐gene panel is the most utilized genetic test to evaluate for germline cancer predisposition syndromes. However, the rate of change of commercial multigene panels is not well understood, and its value as a standalone test has also not been investigated.
Elise G. Williams+4 more
wiley +1 more source
Oral manifestion of Langerhans cell histiocytosis mimicking inflammation
Langerhans cell histiocytosis (LCH) is a rare idiopathic disease characterized by the clonal proliferation of Langerhans cells. LCH affects five children per million population. The peak incidence is from 1 to 4 years of age.
K S Divya
doaj +1 more source
Trapdoor Procedure for Benign Bone Lesions in the Femoral Head of Skeletally Immature Children
This finding of this study suggests that the trapdoor procedure for bone lesions of the femoral head is a safe and effective technique to completely remove the tumors. ABSTRACT Objective Benign bone lesions involving the femoral head are common in pediatric populations but pose significant challenges due to anatomical complexity and the need to ...
Qichao Ma+6 more
wiley +1 more source
Langerhans´cell histiocytosis [PDF]
La histiocitosis de células de Langerhans (HCL), anteriormente conocida como histiocitosis X, es una enfermedad poco frecuente caracterizada por la acumulación y proliferación de histiocitos, eosinófilos y células de Langerhans, con inclusión de gránulos
Casanovas, A., Elena, G., Rosso, Diego
core +1 more source
Multisystem Langerhans cell histiocytosis: Literature review and case report
Langerhans cell histiocytosis (LCH) refers to a group of diseases of unknown etiology, typically discovered in childhood, characterized by the accumulation of Langerhans cells (white blood cells with large cell nuclei that may contain cytoplasmic ...
Cung-Van Cong, MD, PhD+2 more
doaj