Results 41 to 50 of about 5,574,084 (164)

LANGERHANS CELLS HISTIOCYTOSIS IN ONE FAMILY [PDF]

Acta Medica Iranica, 2004
Histiocytosis of Langerhans cells (class 1 histiocytosis) consists of a range of clinical manifestations, including bone eosinophilic granuloma, Hand-Schüller-Christian syndrome, and Letterer-Siwe disease. These syndromes represent a spectrum of severity
Sh. Ansari, P. Vossough H. Haddad Deylami   +1 more
doaj   +1 more source

COMPROMISO OSEO EN HISTIOCITOSIS DE CELULAS DE LANGERHANS EN EL NIÑO: ESTUDIO RADIOLOGICO SIMPLE. PRESENTACION CLINICA Y DIAGNOSTICO RADIOLOGICO

Revista Chilena de Radiología
Introducción. La Histiocitosis de células de Langerhans (HCL) es una patología poco frecuente, con diferentes manifestaciones radio-lógicas. Su causa es desconocida y se caracteriza por una proliferación de las células de Langerhans.
Raúl Rojas C, Cristián García B, Dimitri Parra R, Antonieta Solar G, Roberto Oyanedel Q, Fernán Díaz B, Juan Fortune H, Martín Etchart K   +7 more
doaj   +1 more source

Outcome of treatment with trametinib in adults with histiocytic neoplasms in the United Kingdom

British Journal of Haematology, Volume 209, Issue 2, Page 747-754, August 2026.
Trametinib (MEK inhibitor) shows efficacy in refractory and high‐risk adult histiocytic neoplasms. At a median follow‐up of 21.4 months, the clinical response rate was 81% (30/37) and the radiological response was 68% (25/37) (n = 37).
Rodothea Amerikanou, Talha Munir, Kristian Bowles, Christopher McNamara, Nikesh Chavda, Elizabeth Price, Jagdish Adiyodi, Alasdair Coles, Philippa Kelsey, Jeffery Smith, Richard Adams, Hayder Hussein, Rui Zhao, Trung Nguyen, Matthew Collin, Satyen Gohil   +15 more
wiley   +1 more source

Pulmonary Histiocytosis X

Annals of Saudi Medicine, 1998
g twice a day.In November 1994 she was re-admitted to a secondhospital with a right-sided pneumothorax. In addition tothe pneumothorax, the chest x-ray showed diffuseinterstitial infiltration of both lungs, with normal lungvolumes. Computed tomography (CT) of the chest showeddiffuse interstitial disease, with multiple thin and thick-walled cysts of ...
H, Al-Jahdali, A, Al-Shimemeri, H, Bamefleh, M, Al-Moamary   +3 more
openaire   +2 more sources

2-Chlorodeoxyadenosine to Treat Refractory Histiocytosis X

, 1993
To the Editor: Treatment of histiocytosis X is palliative at best. It includes corticosteroids, alkylating agents, antimetabolites, vinca alkaloids, and irradiation 1 .
Saven, Alan, Joseph D. Rosenblatt, Michael L. Figueroa, Alan Saven, Rosenblatt, Joseph D, Piro, Lawrence D, Lawrence D. Piro, Figueroa, Michael L   +7 more
core   +1 more source

Adult Langerhans cell histiocytosis with pulmonary and colorectoanal involvement: a case report

Journal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a rare systemic disease characterized by the abnormal overproduction of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage. It mainly affects – by order of
Mohamad Jihad Mansour, Elias Mokbel, Eddy Fares, Janah Maddah, Fadi Nasr   +4 more
doaj   +1 more source

Synthetic Ligands of Myeloid C‐Type Lectin Receptors

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley   +1 more source

Chronic Myelogenous Leukemia Following Repeated Radiation Therapy for Histiocytosis X

, 1994
Low dose radiotherapy has been used to treat a variety of benign disorders including Histiocytosis X. Ionizing radiation may be leukemogenic with leukemia developing between 3.5 to 11 years after exposure.
Nimer, Stephen D, Chap, Linnea
core   +1 more source

Multidisciplinary Exploration of Computed‐Tomographic and Ancient‐DNA Data of an Iron Age Skull From Latvia With Multiple Lytic Bone Lesions: Differential Diagnosis Between Metastatic Carcinoma, Multiple Myeloma and Skeletal Tuberculosis

Ecology and Evolution, Volume 16, Issue 7, July 2026.
In this study we used a combined computed tomographic and archaeogenetic approach to analyse a skull and vertebra with lytic lesions from a disturbed grave in the Čunkāni‐Dreņģeri cemetery in Latvia, dated to 10th century CE. Both methodologies were used to evaluate a proposed differential diagnosis of multiple myeloma, metastatic carcinoma and bone ...
Alise Akermane‐Pokšāne, Jānis Ķimsis, Elīna Pētersone‐Gordina, Antonija Vilcāne, Guntis Gerhards, Mārtiņš Pēterfelds, Renāte Ranka   +6 more
wiley   +1 more source

Next‐Generation Paleopathology: Using Commercial AI in Bioarchaeological Diagnosis

International Journal of Osteoarchaeology, Volume 36, Issue 4, Page 844-858, July/August 2026.
ABSTRACT Artificial intelligence encompasses computational systems capable of performing cognitive functions such as learning, reasoning, and problem‐solving. Within this domain, generative AI and large language models such as ChatGPT, Gemini, and Copilot have shown significant potential in clinical diagnostics.
Jessica Mongillo, Giulia Vescovo, Giulia Manzo, Nicoletta Zedda, Barbara Bramanti   +4 more
wiley   +1 more source