Results 51 to 60 of about 5,875,026 (205)

Dynamic Prediction of Clinical Endpoints in Survival Analysis With Machine and Deep Learning: A Systematic Review and Regulatory Perspective

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.
ABSTRACT Accurate prediction of time‐to‐event outcomes is essential for clinical decision‐making and model‐informed drug development (MIDD). Conventional survival models may inadequately represent complex longitudinal patient trajectories, time‐dependent treatments, and evolving biomarker or pharmacokinetic/pharmacodynamic (PK/PD) profiles.
Xinyi Liu   +3 more
wiley   +1 more source

LANGERHANS CELLS HISTIOCYTOSIS IN ONE FAMILY [PDF]

open access: yesActa Medica Iranica, 2004
Histiocytosis of Langerhans cells (class 1 histiocytosis) consists of a range of clinical manifestations, including bone eosinophilic granuloma, Hand-Schüller-Christian syndrome, and Letterer-Siwe disease. These syndromes represent a spectrum of severity
Sh. Ansari   +1 more
doaj   +1 more source

Chronic Kidney Disease in Children Within Five Years After Ifosfamide Chemotherapy for Childhood Cancer: A Dutch Pediatric Oncology Cohort Study

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce.
Lotte Pitlo   +9 more
wiley   +1 more source

Adult Langerhans cell histiocytosis with pulmonary and colorectoanal involvement: a case report

open access: yesJournal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a rare systemic disease characterized by the abnormal overproduction of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage. It mainly affects – by order of
Mohamad Jihad Mansour   +4 more
doaj   +1 more source

Pulmonary langerhans cell granulomatosis (histiocytosis X)

open access: yesТуберкулез и болезни лёгких, 2014
Pulmonary Langerhans cell granulomatosis is a rare disease. Its causes are unknown and accurate data on its prevalence are lacking. This disease is characterized by the formation of lung tissue granulomas consisting of activated Langerhans cells ...
A. A. Sadovnikov, K. I. Panchenko
doaj  

Ventilation Imaging of the Lung at 0.55T With Continuous Slice Cycling

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 3, Page 1235-1244, September 2026.
ABSTRACT Purpose To propose and evaluate a novel method for pulmonary ventilation imaging, offering considerably improved SNR. Methods A continuous slice cycling (CSC) acquisition scheme is proposed to exclusively capture signal modulations from respiratory motion with increased SNR.
Andrea Leuthard   +4 more
wiley   +1 more source

Histiocytosis X: Langerhans’ Cell Histiocytosis

open access: yesHematology/Oncology Clinics of North America, 1987
Histiocytosis X is a complex and poorly understood entity. Nevertheless, it would appear as if certain themes are found recurrently throughout the literature dealing with this disease and a review of them serves as a useful summary. 1. Problems with Nomenclature.
openaire   +2 more sources

Diagnostic problems and surgical treatment of histiocytosis X [PDF]

open access: yesMedicinski Glasnik, 2007
A 16-year-old boy, with swelling and pain in the left submandibular region was treated at the Clinic for Maxillofacial Surgery. The x-ray examination showed destructive bone lesion of the mandibulae left side and oval lesions on the left hand bone and ...
Alkhalil M, A. Redžić, A. Smajilagić
doaj  

Chronic Recurrent Multifocal Osteomyelitis in a Pediatric Patient: An Uncommon Case With Diagnostic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare autoinflammatory bone disorder that primarily affects children and adolescents. It is characterized by recurrent episodes of bone pain with sterile inflammatory lesions, often resembling infection or malignancy.
Dosti Regmi   +4 more
wiley   +1 more source

Clinical experience in an infant with Langerhans cell histiocytosis

open access: yesUniversidad Médica Pinareña, 2021
Introduction: Langerhans cell histiocytosis (LCH) or Histiocytosis X is a benign proliferative disease affecting dendritic cells. It presents a wide clinical spectrum, from isolated eosinophilic bone granuloma to multisystem involvement with multiple ...
Yamilka Pita Barrios   +2 more
doaj  

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