Results 1 to 10 of about 49,950 (108)

Maternal and Infant Histo-Blood Group Antigen (HBGA) Profiles and Their Influence on Oral Rotavirus Vaccine (Rotarix^TM) Immunogenicity among Infants in Zambia [PDF]

Vaccines, 2023
Live-attenuated, oral rotavirus vaccines have significantly reduced rotavirus-associated diarrhoea morbidity and infant mortality. However, vaccine immunogenicity is diminished in low-income countries.
Adriace Chauwa, Samuel Bosomprah, Natasha Makabilo Laban, Bernard Phiri, Mwelwa Chibuye, Obvious Nchimunya Chilyabanyama, Sody Munsaka, Michelo Simuyandi, Innocent Mwape, Cynthia Mubanga, Masuzyo Chirwa Chobe, Caroline Chisenga, Roma Chilengi   +12 more
doaj   +3 more sources

Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants [PDF]

Gut Microbes, 2021
The study tested the hypothesis that harboring high levels of histo-blood group antigen-expressing Enerobactero cloacae is a risk factor for norovirus diarrhea. The fecal E. cloacae abundance in diarrheic norovirus positive (DNP), non-diarrheic norovirus
Cliff A Magwira, Duncan Steele, ML Seheri   +2 more
doaj   +3 more sources

Histo-Blood Group Antigen-Producing Bacterial Cocktail Reduces Rotavirus A, B, and C Infection and Disease in Gnotobiotic Piglets [PDF]

Viruses
The suboptimal performance of rotavirus (RV) vaccines in developing countries and in animals necessitates further research on the development of novel therapeutics and control strategies.
Sergei A. Raev, Maryssa K. Kick, Maria Chellis, Joshua O. Amimo, Linda J. Saif, Anastasia N. Vlasova   +5 more
doaj   +3 more sources

Binding to histo-blood group antigen-expressing bacteria protects human norovirus from acute heat stress [PDF]

Frontiers in Microbiology, 2015
This study aims to investigate if histo-blood group antigen (HBGA) expressing bacteria have any protective role on human norovirus (NoV) from acute heat stress.
Dan eLi, Adrien eBreiman, Adrien eBreiman, Adrien eBreiman, Adrien eBreiman, Jacques eLe Pendu, Jacques eLe Pendu, Jacques eLe Pendu, Mieke eUyttendaele   +8 more
doaj   +3 more sources

Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates [PDF]

Viruses, 2019
Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain.
Malak A. Esseili, Xiang Gao, Patricia Boley, Yixuan Hou, Linda J. Saif, Paul Brewer-Jensen, Lisa C. Lindesmith, Ralph S. Baric, Robert L. Atmar, Qiuhong Wang   +9 more
doaj   +3 more sources

Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles [PDF]

mBio, 2018
Emerging zoonotic viral diseases remain a challenge to global public health. Recent surveillance studies have implicated bats as potential reservoirs for a number of viral pathogens, including coronaviruses and Ebola viruses.
Jacob F. Kocher, Lisa C. Lindesmith, Kari Debbink, Anne Beall, Michael L. Mallory, Boyd L. Yount, Rachel L. Graham, Jeremy Huynh, J. Edward Gates, Eric F. Donaldson, Ralph S. Baric   +10 more
doaj   +3 more sources

Inhibition of histo-blood group antigen binding as a novel strategy to block norovirus infections. [PDF]

PLoS ONE, 2013
Noroviruses (NoVs) are the most important viral pathogens that cause epidemic acute gastroenteritis. NoVs recognize human histo-blood group antigens (HBGAs) as receptors or attachment factors.
Xu-Fu Zhang, Ming Tan, Monica Chhabra, Ying-Chun Dai, Jarek Meller, Xi Jiang   +5 more
doaj   +3 more sources

Lack of Norovirus Replication and Histo-Blood Group Antigen Expression in 3-Dimensional Intestinal Epithelial Cells [PDF]

Emerging Infectious Diseases, 2013
Noroviruses (NoVs) are a leading cause of gastroenteritis worldwide. An in vitro model for NoV replication remains elusive, making study of the virus difficult.
Melissa M. Herbst-Kralovetz, Andrea L. Radtke, Margarita K. Lay, Brooke E. Hjelm, Alice N. Bolick, Shameema S. Sarker, Robert L. Atmar, David H. Kingsley, Charles J. Arntzen, Mary K. Estes, Cheryl A. Nickerson   +10 more
doaj   +3 more sources

Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. [PDF]

J Virol, 2023
Human noroviruses are highly contagious and a major problem in closed institutions, such as schools, hospitals, and cruise ships. Reducing norovirus infections is challenging on multiple levels and includes the frequent emergence of antigenic variants ...
Kher G, Sabin C, Lun JH, Devant JM, Ruoff K, Koromyslova AD, von Itzstein M, Pancera M, Hansman GS.   +8 more
europepmc   +2 more sources

Histo-Blood Group Antigen Null Phenotypes Associated With a Decreased Risk of Clinical Rotavirus Vaccine Failure Among Children <2 Years of Age Participating in the Vaccine Impact on Diarrhea in Africa (VIDA) Study in Kenya, Mali, and the Gambia. [PDF]

Clin Infect Dis, 2023
Background Previously studied risk factors for rotavirus vaccine failure have not fully explained reduced rotavirus vaccine effectiveness in low-income settings.
Schwartz LM, Oshinsky J, Reymann M, Esona MD, Bowen MD, Jahangir Hossain M, Zaman SMA, Jones JCM, Antonio M, Badji H, Sarwar G, Sow SO, Sanogo D, Keita AM, Tamboura B, Traoré A, Onwuchekwa U, Omore R, Verani JR, Awuor AO, Ochieng JB, Juma J, Ogwel B, Parashar UD, Tate JE, Kasumba IN, Tennant SM, Neuzil KM, Rowhani-Rahbar A, Elizabeth Halloran M, Atmar RL, Pasetti MF, Kotloff KL.   +32 more
europepmc   +2 more sources