Histo-Blood Group Antigen-Producing Bacterial Cocktail Reduces Rotavirus A, B, and C Infection and Disease in Gnotobiotic Piglets [PDF]
VirusesThe suboptimal performance of rotavirus (RV) vaccines in developing countries and in animals necessitates further research on the development of novel therapeutics and control strategies.
Sergei A. Raev +5 more
doaj +5 more sources
Structural constraints prevent a bat norovirus from binding to histo-blood group antigen co-factors [PDF]
Journal of VirologyDayna L. Holroyd +3 more
doaj +4 more sources
Relationship Between Rotavirus P[6] Infection in Korean Neonates and Histo-Blood Group Antigen: a Single-Center Study. [PDF]
Ann Lab Med, 2021 Background Rotaviruses are a major cause of pediatric gastroenteritis. The rotavirus P[6] genotype is the most prevalent genotype isolated from Korean neonates but has rarely been reported in other countries.
Lee SK +8 more
europepmc +3 more sources
Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. [PDF]
J Virol, 2023 Human noroviruses are highly contagious and a major problem in closed institutions, such as schools, hospitals, and cruise ships. Reducing norovirus infections is challenging on multiple levels and includes the frequent emergence of antigenic variants ...
Kher G +8 more
europepmc +4 more sources
Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women. [PDF]
PLoS Genetics, 2008 While circulating levels of soluble Intercellular Adhesion Molecule 1 (sICAM-1) have been associated with diverse conditions including myocardial infarction, stroke, malaria, and diabetes, comprehensive analysis of the common genetic determinants of ...
Guillaume Paré +7 more
doaj +5 more sources
Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants [PDF]
Gut Microbes, 2021 The study tested the hypothesis that harboring high levels of histo-blood group antigen-expressing Enerobactero cloacae is a risk factor for norovirus diarrhea. The fecal E. cloacae abundance in diarrheic norovirus positive (DNP), non-diarrheic norovirus
Cliff A Magwira +2 more
doaj +3 more sources
Binding to histo-blood group antigen-expressing bacteria protects human norovirus from acute heat stress [PDF]
Frontiers in Microbiology, 2015 This study aims to investigate if histo-blood group antigen (HBGA) expressing bacteria have any protective role on human norovirus (NoV) from acute heat stress.
Dan eLi +8 more
doaj +3 more sources
Human Norovirus Histo-Blood Group Antigen (HBGA) Binding Sites Mediate the Virus Specific Interactions with Lettuce Carbohydrates [PDF]
Viruses, 2019 Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain.
Malak A. Esseili +9 more
doaj +3 more sources
Human Neonatal Rotavirus Vaccine (RV3-BB) Produces Vaccine Take Irrespective of Histo-Blood Group Antigen Status. [PDF]
J Infect Dis, 2020 Background VP4 [P] genotype binding specificities of rotaviruses and differential expression of histo-blood group antigens (HBGAs) between populations may contribute to reduced efficacy against severe rotavirus disease.
Boniface K +4 more
europepmc +4 more sources
Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles [PDF]
mBio, 2018 Emerging zoonotic viral diseases remain a challenge to global public health. Recent surveillance studies have implicated bats as potential reservoirs for a number of viral pathogens, including coronaviruses and Ebola viruses.
Jacob F. Kocher +10 more
doaj +3 more sources