Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection [PDF]
Viruses, 2019 Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín +5 more
doaj +6 more sources
Norovirus Binding to Ligands Beyond Histo-Blood Group Antigens [PDF]
Frontiers in Microbiology, 2017 Histo-blood group antigens (HBGAs) are commonly accepted as the cellular receptors for human norovirus. However, some human noroviruses have been found not to bind any HBGA ligand, suggesting potential additional co-factors.
Erin A. Almand +3 more
doaj +5 more sources
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis [PDF]
FEBS Open Bio, 2022 Noroviruses have been identified as major causative agents of acute nonbacterial gastroenteritis in humans. Histo‐blood group antigens (HBGAs) are thought to play a major role among the host cellular factors influencing norovirus infection.
Tomomi Kimura‐Someya +7 more
doaj +3 more sources
Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens [PDF]
mSphere, 2016 Human norovirus interacts with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. The genogroup II genotype 4 (GII.4) noroviruses are the dominant cluster, evolve every other year, and
Bishal K. Singh +2 more
doaj +3 more sources
The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae [PDF]
Microbiology Spectrum, 2022 Human norovirus (HuNoV) is the major agent for viral gastroenteritis, causing >700 million infections yearly. Fucose-containing carbohydrates named histo-blood group antigens (HBGAs) are known (co)receptors for HuNoV.
Arno Cuvry +6 more
doaj +2 more sources
Journal of Microbiology, Immunology and Infection, 2023 Background: Pseudomonas aeruginosa is not a common enteric pathogen. The association between human histo-blood group antigens (HBGAs) and P. aeruginosa enteric infection has not yet been studied.
Chih-Hsien Chuang +5 more
doaj +3 more sources
Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens. [PDF]
PLoS Pathogens, 2020 Initial cell attachment of rotavirus (RV) to specific cell surface glycan receptors, which is the essential first step in RV infection, is mediated by the VP8* domain of the spike protein VP4.
Shenyuan Xu +10 more
doaj +2 more sources
Norovirus binding to intestinal epithelial cells is independent of histo-blood group antigens. [PDF]
PLoS ONE, 2013 Human noroviruses (NoVs) are a major cause of non-bacterial gastroenteritis. Although histo-blood group antigens (HBGAs) have been implicated in the initial binding of NoV, the mechanism of that binding before internalization is not clear.
Kosuke Murakami +11 more
doaj +2 more sources
Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens. [PDF]
PLoS Pathogens, 2019 Rotavirus is the leading agent causing acute gastroenteritis in young children, with the P[8] genotype accounting for more than 80% of infections in humans.
Roberto Gozalbo-Rovira +8 more
doaj +2 more sources
Structural basis of P[II] rotavirus evolution and host ranges under selection of histo-blood group antigens [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2021 Michael Kennedy +2 more
exaly +2 more sources