Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection [PDF]
Viruses, 2019 Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín +5 more
doaj +8 more sources
Norovirus Binding to Ligands Beyond Histo-Blood Group Antigens [PDF]
Frontiers in Microbiology, 2017 Histo-blood group antigens (HBGAs) are commonly accepted as the cellular receptors for human norovirus. However, some human noroviruses have been found not to bind any HBGA ligand, suggesting potential additional co-factors.
Erin A. Almand +3 more
doaj +7 more sources
Norovirus Recognition Sites on Histo-blood Group Antigens [PDF]
Frontiers in Microbiology, 2012 Norovirus (NoV) is the major causative agent of acute viral gastroenteritis worldwide. Based on genetic analyses, human NoV strains have been classified into at least three genogroups: genogroup I (GI), GII, and GIV, which contain at least 15, 18, and 1 genotypes, respectively (Kageyama et al., 2004).
Haruko eShirato
doaj +5 more sources
Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens [PDF]
mSphere, 2016 Human norovirus interacts with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. The genogroup II genotype 4 (GII.4) noroviruses are the dominant cluster, evolve every other year, and
Bishal K. Singh +2 more
doaj +6 more sources
Genogroup IV and VI canine noroviruses interact with histo-blood group antigens. [PDF]
J Virol, 2014 UNLABELLED: Human noroviruses (HuNV) are a significant cause of viral gastroenteritis in humans worldwide. HuNV attaches to cell surface carbohydrate structures known as histo-blood group antigens (HBGAs) prior to internalization, and HBGA polymorphism ...
Caddy S +3 more
europepmc +7 more sources
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis [PDF]
FEBS Open Bio, 2022 Noroviruses have been identified as major causative agents of acute nonbacterial gastroenteritis in humans. Histo‐blood group antigens (HBGAs) are thought to play a major role among the host cellular factors influencing norovirus infection.
Tomomi Kimura‐Someya +7 more
doaj +2 more sources
The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae [PDF]
Microbiology Spectrum, 2022 Human norovirus (HuNoV) is the major agent for viral gastroenteritis, causing >700 million infections yearly. Fucose-containing carbohydrates named histo-blood group antigens (HBGAs) are known (co)receptors for HuNoV.
Arno Cuvry +6 more
doaj +2 more sources
Histo-Blood Group Antigens in Oral Cancer and Potentially Malignant Disorders. [PDF]
Asian Pac J Cancer Prev, 2020 Early detection of oral cancer is of critical importance because survival rates markedly improve when oral lesions are identified at an early stage. Aim of the present study is to investigate the expression of ABO (H) antigens in tissue specimens of oral cancer and potentially malignant disorders and to determine the role of ABO (H) antigens in tumour ...
Pokala A +5 more
europepmc +4 more sources
Human noroviruses' fondness for histo-blood group antigens. [PDF]
J Virol, 2015 ABSTRACT Human noroviruses are the dominant cause of outbreaks of gastroenteritis around the world. Human noroviruses interact with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. Indeed, synthetic HBGAs or HBGA-expressing enteric bacteria were shown to enhance norovirus
Singh BK, Leuthold MM, Hansman GS.
europepmc +4 more sources
Histo-blood group antigens and rotavirus vaccine shedding in Nicaraguan infants. [PDF]
Sci Rep, 2019 AbstractABO, Lewis and secretor histo-blood group antigens (HBGA) are susceptibility factors for rotavirus in a P-genotype dependent manner and can influence IgA seroconversion rates following rotavirus vaccination. To investigate the association between HBGA phenotypes and rotavirus vaccine shedding fecal samples (n = 304) from a total of 141 infants ...
Bucardo F +6 more
europepmc +5 more sources