Results 31 to 40 of about 13,139 (185)
The tandem-repeat Galectin-4 (Gal-4) contains two different domains covalently linked through a short flexible peptide. Both domains have been shown to bind preferentially to A and B histo blood group antigens with different affinities, although the ...
Jon I. Quintana +11 more
doaj +1 more source
Rotaviruses (RVs) are the leading cause of acute gastroenteritis in children, while histo-blood group antigens (HBGAs) are believed to be host attachment and susceptibility factors of RVs.
Jin-Xia Wang +14 more
doaj +1 more source
Affinities of human histo-blood group antigens for norovirus capsid protein complexes. [PDF]
The binding profiles of many human noroviruses (huNoVs) for human histo-blood group antigens have been characterized. However, quantitative-binding data for these important virus–host interactions are lacking.
Han L +6 more
europepmc +2 more sources
The FUT2 α1,2fucosyltransferase contributes to the synthesis of fucosylated glycans used as attachment factors by several pathogens, including noroviruses and rotaviruses, that can induce life-threatening gastroenteritis in young children.
Emmanuelle Godefroy +13 more
doaj +1 more source
Expression of histo-blood group antigens in bronchial squamous metaplasia [PDF]
The aim of the present study was to evaluate the expression of blood group antigens in squamous bronchial metaplasia in order to determine whether this factor could identify patients at risk of lung cancer.In total, 100 bronchial biopsies were included in the present study.
N, Sánchez-Mora +4 more
openaire +2 more sources
Association of Histo–Blood Group Antigens and Susceptibility to Norovirus Infections [PDF]
Noroviruses (NoVs) are the leading cause of viral gastroenteritis in humans of all ages. Challenge studies that used the NoV prototype strain Norwalk virus (NV) have shown that some individuals are not susceptible to infection, suggesting the absence of a receptor. Recent studies have identified histo-blood group antigens (HBGAs) as possible receptors.
Barry H G, Rockx +4 more
openaire +4 more sources
Background Histo-blood group antigens (HBGAs) which include the ABO and Lewis antigen systems have been known for determining predisposition to infections. For instance, blood group O individuals have a higher risk of severe illness due to V.
Caroline C. Chisenga +9 more
doaj +1 more source
Intestinal mucin-type O-glycans: the major players in the host-bacteria-rotavirus interactions
Rotavirus (RV) causes severe diarrhea in young children and animals worldwide. Several glycans terminating in sialic acids (SAs) and histo-blood group antigens (HBGAs) on intestinal epithelial cell (IEC) surface have been recognized to act as attachment ...
S.A. Raev +3 more
doaj +1 more source
Histo-Blood Group Antigen Assay for Detecting Noroviruses in Water [PDF]
ABSTRACT We evaluated a novel, magnetic-bead-based histo-blood group antigen assay for the recovery of low numbers of norovirus particles. Using this assay, with Norwalk virus seeded in environmental waters as a model, we were able to recover 30 to 300 genomic copies of the virus.
Jennifer L, Cannon, Jan, Vinjé
openaire +2 more sources
Diversity in RotavirusâHost Glycan Interactions: A âSweetâ SpectrumSummary
Interaction with cellular glycans is a critical initial step in the pathogenesis of many infectious agents. Technological advances in glycobiology have expanded the repertoire of studies delineating host glycanâpathogen interactions. For rotavirus, the
Sasirekha Ramani +3 more
doaj +1 more source

