Results 31 to 40 of about 13,189,508 (152)

Genetic Susceptibility to Human Norovirus Infection: An Update

Viruses, 2019
Noroviruses are the most common etiological agent of acute gastroenteritis worldwide. Despite their high infectivity, a subpopulation of individuals is resistant to infection and disease. This susceptibility is norovirus genotype-dependent and is largely
Johan Nordgren, Lennart Svensson
doaj   +1 more source

A spoonful of sugar helps the viruses go down

Journal of Pediatric and Neonatal Individualized Medicine, 2022
Studies that attempt to deepen how pathogens try to circumvent the immune system and stimulate understanding of the mechanisms, can boost our knowledge on the process of viral infection, immune response circumvention and disease development.
Ruggiero Francavilla
doaj   +1 more source

Intestinal mucin-type O-glycans: the major players in the host-bacteria-rotavirus interactions

Gut Microbes, 2023
Rotavirus (RV) causes severe diarrhea in young children and animals worldwide. Several glycans terminating in sialic acids (SAs) and histo-blood group antigens (HBGAs) on intestinal epithelial cell (IEC) surface have been recognized to act as attachment ...
S.A. Raev, J.O. Amimo, L.J. Saif, A.N. Vlasova   +3 more
doaj   +1 more source

Affinities of recombinant norovirus P dimers for human blood group antigens [PDF]

, 2013
Noroviruses (NoVs), the major cause of viral acute gastroenteritis, recognize histo-blood group antigens (HBGAs) as receptors or attachment factors.
Kitova, Elena N., Wang, Leyi, Xia, Ming, Jiang, Xi, Han, Ling, Klassen, John S., Tan, Ming, Kitov, Pavel I.   +7 more
core   +3 more sources

Assessment of the influence of ABO blood groups on oral cholera vaccine immunogenicity in a cholera endemic area in Zambia

BMC Public Health, 2023
Background Histo-blood group antigens (HBGAs) which include the ABO and Lewis antigen systems have been known for determining predisposition to infections. For instance, blood group O individuals have a higher risk of severe illness due to V.
Caroline C. Chisenga, Samuel Bosomprah, Obvious N. Chilyabanyama, Peter Alabi, Michelo Simuyandi, John Mwaba, Harriet Ng’ombe, Natasha M. Laban, Charlie C. Luchen, Roma Chilengi   +9 more
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Intestinal shedding of enteric agents in histo-blood group antigen-secretor children in an Australian community-based birth cohort study

Journal of Pediatric and Neonatal Individualized Medicine, 2022
Histo-blood group antigens are inherited polymorphic glycans expressed on mucosal epithelial cell surfaces and shed in secretions. They act as receptors for gastrointestinal pathogens. Those expressing these antigens are categorized as secretors and have
Gabor Mihala, Robert S. Ware, Catherine Cheung, Stephen B. Lambert, Peter D. Sly, David M. Whiley, Keith Grimwood   +6 more
doaj   +1 more source

Binding to histo-blood group antigen-expressing bacteria protects human norovirus from acute heat stress

Frontiers in Microbiology, 2015
This study aims to investigate if histo-blood group antigen (HBGA) expressing bacteria have any protective role on human norovirus (NoV) from acute heat stress.
Dan eLi, Adrien eBreiman, Adrien eBreiman, Adrien eBreiman, Adrien eBreiman, Jacques eLe Pendu, Jacques eLe Pendu, Jacques eLe Pendu, Mieke eUyttendaele   +8 more
doaj   +1 more source

Species-Specific N-Glycomes and Methylation Patterns of Oysters Crassostrea gigas and Ostrea edulis and Their Possible Consequences for the Norovirus–HBGA Interaction

Marine Drugs, 2023
Noroviruses, the major cause of acute viral gastroenteritis, are known to bind to histo-blood group antigens (HBGAs), including ABH groups and Lewis-type epitopes, which decorate the surface of erythrocytes and epithelial cells of their host tissues. The
Audrey Auger, Shin-Yi Yu, Shih-Yun Guu, Agnès Quéméner, Gabriel Euller-Nicolas, Hiromune Ando, Marion Desdouits, Françoise S. Le Guyader, Kay-Hooi Khoo, Jacques Le Pendu, Frederic Chirat, Yann Guerardel   +11 more
doaj   +1 more source

Immune Imprinting Drives Human Norovirus Potential for Global Spread

mBio, 2022
Understanding the complex interactions between virus and host that drive new strain evolution is key to predicting the emergence potential of variants and informing vaccine development. Under our hypothesis, future dominant human norovirus GII.4 variants
Lisa C. Lindesmith, Florencia A. T. Boshier, Paul D. Brewer-Jensen, Sunando Roy, Veronica Costantini, Michael L. Mallory, Mark Zweigart, Samantha R. May, Helen Conrad, Kathleen M. O’Reilly, Daniel Kelly, Cristina C. Celma, Stuart Beard, Rachel Williams, Helena J. Tutill, Sylvia Becker Dreps, Filemón Bucardo, David J. Allen, Jan Vinjé, Richard A. Goldstein, Judith Breuer, Ralph S. Baric   +21 more
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Epidemiology of enteric virus infections in children living in the Amazon region

International Journal of Infectious Diseases, 2021
Objectives: To verify the frequency of viruses causing acute gastroenteritis (AGE) in association with the histo-blood group antigen (HBGA) and Rotarix™ vaccination coverage in children from the Amazon region.
Alberto Ignacio Olivares Olivares, Gabriel Azevedo Alves Leitão, Yan Cardoso Pimenta, Carina Pacheco Cantelli, Tulio Machado Fumian, Alexandre Madi Fialho, Sergio da Silva e Mouta, Junior, Isabella Fernandes Delgado, Johan Nordgren, Lennart Svensson, Marize Pereira Miagostovich, José Paulo Gagliardi Leite, Marcia Terezinha Baroni de Moraes   +12 more
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