Results 21 to 30 of about 13,189,508 (152)

Affinities of human histo-blood group antigens for norovirus capsid protein complexes. [PDF]

open access: yesGlycobiology, 2015
The binding profiles of many human noroviruses (huNoVs) for human histo-blood group antigens have been characterized. However, quantitative-binding data for these important virus–host interactions are lacking.
Han L   +6 more
europepmc   +4 more sources

Histo-blood group antigens and rotavirus vaccine virus shedding in Australian infants

open access: yes, 2022
Histo-blood group antigens and rotavirus vaccine virus shedding in Australian ...
SB Lambert (14457444)   +7 more
core   +2 more sources

The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease

open access: yesInternational Journal of Medical Microbiology, 2021
The glycosylation profile of the gastrointestinal tract is an important factor mediating host-microbe interactions. Variation in these glycan structures is often mediated by blood group-related glycosyltransferases, and can lead to wide-ranging ...
Alibek Galeev   +5 more
doaj   +1 more source

Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations

open access: yesFrontiers in Chemistry, 2021
The tandem-repeat Galectin-4 (Gal-4) contains two different domains covalently linked through a short flexible peptide. Both domains have been shown to bind preferentially to A and B histo blood group antigens with different affinities, although the ...
Jon I. Quintana   +11 more
doaj   +1 more source

Genetic susceptibility to rotavirus infection in Chinese children: a population-based case–control study

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Rotaviruses (RVs) are the leading cause of acute gastroenteritis in children, while histo-blood group antigens (HBGAs) are believed to be host attachment and susceptibility factors of RVs.
Jin-Xia Wang   +14 more
doaj   +1 more source

Norovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens. [PDF]

open access: yesAntiviral Res, 2016
Human noroviruses are the leading causative agents of epidemic and sporadic viral gastroenteritis and childhood diarrhoea worldwide. Human histo-blood group antigens (HBGA) serve as receptors for norovirus capsid protein attachment and play a critical ...
Ali ES   +3 more
europepmc   +2 more sources

Norovirus Capture with Histo-Blood Group Antigens Reveals Novel Virus-Ligand Interactions [PDF]

open access: yes, 2004
Noroviruses are genetically diverse, uncultivable, positive-sense RNA viruses and are the most common cause of epidemic acute gastroenteritis in humans in the United States.
Vinje, J.   +3 more
core   +1 more source

ABO blood groups and expression of blood group antigens of epithelial ovarian cancer in Chinese women

open access: yesCancer Medicine, 2023
Background ABO blood groups has been associated with risk of several cancers; however, the results for an association with ovarian cancer are inconsistent and little is known about the expression of histo‐blood group (ABH) antigens and ABO gene in ...
Chao Wang   +15 more
doaj   +1 more source

Microbiota-induced regulatory T cells associate with FUT2-dependent susceptibility to rotavirus gastroenteritis

open access: yesFrontiers in Microbiology, 2023
The FUT2 α1,2fucosyltransferase contributes to the synthesis of fucosylated glycans used as attachment factors by several pathogens, including noroviruses and rotaviruses, that can induce life-threatening gastroenteritis in young children.
Emmanuelle Godefroy   +13 more
doaj   +1 more source

Diversity in Rotavirus–Host Glycan Interactions: A “Sweet” SpectrumSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2016
Interaction with cellular glycans is a critical initial step in the pathogenesis of many infectious agents. Technological advances in glycobiology have expanded the repertoire of studies delineating host glycan–pathogen interactions. For rotavirus, the
Sasirekha Ramani   +3 more
doaj   +1 more source

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