Results 21 to 30 of about 17,546 (202)
Rotavirus VP8*: phylogeny, host range, and interaction with histo-blood group antigens. [PDF]
J Virol, 2012 ABSTRACT The distal portion of rotavirus (RV) VP4 spike protein (VP8*) is implicated in binding to cellular receptors, thereby facilitating viral attachment and entry. While VP8* of some animal RVs engage sialic acid, human RVs often attach to and enter cells in a sialic acid-independent manner.
Liu Y +8 more
europepmc +4 more sources
Frontiers in Cellular and Infection Microbiology, 2021 The glycosyltransferases encoded by genes from the human ABO, Lewis, and Secretor histo-blood group systems synthesize part of the carbohydrate antigens in hematopoietic and non-hematopoietic tissues.
Luiz Carlos De Mattos +5 more
doaj +1 more source
Lewis b antigen is a common ligand for genogroup I norovirus strains
FEBS Open Bio, 2022 Noroviruses are major causative agents of nonbacterial acute gastroenteritis in humans. Ten genogroups of noroviruses have been identified to date, among which genogroup I (GI) and genogroup II (GII) noroviruses are major pathogens for humans. GI and GII
Yuichi Someya
doaj +1 more source
Harnessing marine sulfated polysaccharides to inhibit norovirus: from seaweed to solution [PDF]
Microbiology SpectrumBarbara C. Wimmer +4 more
doaj +2 more sources
Frontiers in Chemistry, 2021 The tandem-repeat Galectin-4 (Gal-4) contains two different domains covalently linked through a short flexible peptide. Both domains have been shown to bind preferentially to A and B histo blood group antigens with different affinities, although the ...
Jon I. Quintana +11 more
doaj +1 more source
International Journal of Medical Microbiology, 2021 The glycosylation profile of the gastrointestinal tract is an important factor mediating host-microbe interactions. Variation in these glycan structures is often mediated by blood group-related glycosyltransferases, and can lead to wide-ranging ...
Alibek Galeev +5 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Rotaviruses (RVs) are the leading cause of acute gastroenteritis in children, while histo-blood group antigens (HBGAs) are believed to be host attachment and susceptibility factors of RVs.
Jin-Xia Wang +14 more
doaj +1 more source
Histo-blood group antigens as mediators of infections [PDF]
Current Opinion in Structural Biology, 2017 The critical first step of a microbial infection is usually the attachment of pathogens to host cell glycans. Targets on host tissues are in particular the histo-blood group antigens (HBGAs), which are present in rich diversity in the mucus layer and on the underlying mucosa.
Heggelund, Julie E. +3 more
openaire +3 more sources
Minimizing the Entropy Penalty for Ligand Binding: Lessons from the Molecular Recognition of the Histo Blood-Group Antigens by Human Galectin-3. [PDF]
Angew Chem Int Ed Engl, 2019 Gimeno A +11 more
europepmc +2 more sources
Blood ties: ABO is a trans-species polymorphism in primates [PDF]
, 2012 The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes ...
A. Venkat +38 more
core +3 more sources