Results 41 to 50 of about 10,874,130 (155)

Epidemiology of enteric virus infections in children living in the Amazon region

International Journal of Infectious Diseases, 2021
Objectives: To verify the frequency of viruses causing acute gastroenteritis (AGE) in association with the histo-blood group antigen (HBGA) and Rotarix™ vaccination coverage in children from the Amazon region.
Alberto Ignacio Olivares Olivares, Gabriel Azevedo Alves Leitão, Yan Cardoso Pimenta, Carina Pacheco Cantelli, Tulio Machado Fumian, Alexandre Madi Fialho, Sergio da Silva e Mouta, Junior, Isabella Fernandes Delgado, Johan Nordgren, Lennart Svensson, Marize Pereira Miagostovich, José Paulo Gagliardi Leite, Marcia Terezinha Baroni de Moraes   +12 more
doaj   +1 more source

Norovirus Infection and Disease in an Ecuadorian Birth Cohort: Association of Certain Norovirus Genotypes With Host FUT2 Secretor Status. [PDF]

, 2015
BACKGROUND: Although norovirus is the most common cause of gastroenteritis, there are few data on the community incidence of infection/disease or the patterns of acquired immunity or innate resistance to norovirus.
Broncano, N, Vicuña, Y, Collins, N, Lopman, BA, Vaca, M, Chico, ME, Vinjé, J, Sandoval, C, Trivedi, T, Costantini, V, Parashar, U, Gregoricus, N, Cooper, PJ, Cooper, Philip John   +13 more
core   +1 more source

Histo-blood group antigens as receptors for rotavirus, new understanding on rotavirus epidemiology and vaccine strategy. [PDF]

Emerg Microbes Infect, 2017
The success of the two rotavirus (RV) vaccines (Rotarix and RotaTeq) in many countries endorses a live attenuated vaccine approach against RVs. However, the lower efficacies of both vaccines in many low- and middle-income countries indicate a need to ...
Jiang X, Liu Y, Tan M.
europepmc   +2 more sources

Norovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens. [PDF]

Antiviral Res, 2016
Human noroviruses are the leading causative agents of epidemic and sporadic viral gastroenteritis and childhood diarrhoea worldwide. Human histo-blood group antigens (HBGA) serve as receptors for norovirus capsid protein attachment and play a critical ...
Ali ES, Rajapaksha H, Carr JM, Petrovsky N.   +3 more
europepmc   +2 more sources

Specific Interactions between Human Norovirus and Environmental Matrices: Effects on the Virus Ecology

Viruses, 2019
Human norovirus is the major cause of non-bacterial epidemic gastroenteritis. Human norovirus binds to environmental solids via specific and non-specific interactions, and several specific receptors for human norovirus have been reported.
Mohan Amarasiri, Daisuke Sano
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Histo-blood group antigens as allo- and autoantigens

, 2005
The science of blood groups has made giant steps forward during the last decade. Blood-group typing of red blood cells (RBCs) is performed on more than 15 million samples per year in Europe, today much less often for forensic reasons than for clinical ...
Tevaearai, Hendrik, THIERRY CARREL, PASCAL BERDAT, ROBERT RIEBEN, WILLY A. FLEGEL, Rieben, Robert, Mohacsi, Paul, Flegel, Willy A, URS E. NYDEGGER, Nydegger, Urs E, Carrel, Thierry, PAUL MOHACSI, Berdat, Pascal, HENDRIK TEVAEARAI   +13 more
core   +1 more source

Low Levels of Natural Anti-α-N-Acetylgalactosamine (Tn) Antibodies Are Associated With COVID-19

Frontiers in Microbiology, 2021
Human serum contains large amounts of anti-carbohydrate antibodies, some of which may recognize epitopes on viral glycans. Here, we tested the hypothesis that such antibodies may confer protection against COVID-19 so that patients would be preferentially
Adrien Breiman, Adrien Breiman, Nathalie Ruvoën-Clouet, Nathalie Ruvoën-Clouet, Marie Deleers, Marie Deleers, Tiffany Beauvais, Tiffany Beauvais, Nicolas Jouand, Jézabel Rocher, Nicolai Bovin, Nathalie Labarrière, Hanane El Kenz, Hanane El Kenz, Jacques Le Pendu   +14 more
doaj   +1 more source

Biology, ecology, and conservation of the Italian hare Lepus corsicanus: a review

Wildlife Biology, EarlyView.
The Italian hare Lepus corsicanus, an endemic lagomorph of Italy, serves as a critical case study in evolutionary biology and conservation. Once taxonomically debated, modern genetic and morphological analyses confirm its status as a distinct Pleistocene lineage restricted to the central‐southern Italian Peninsula and Sicily.
Pierangelo Freschi, Valter Trocchi
wiley   +1 more source

A post-translational modification of human Norovirus capsid protein attenuates glycan binding

Nature Communications, 2019
Attachment of human noroviruses to histo blood group antigens (HBGAs) is essential for infection. Here the authors report that an asparagine residue located near the HBGA-attachment site can convert into an iso-aspartate residue through spontaneous ...
Alvaro Mallagaray, Robert Creutznacher, Jasmin Dülfer, Philipp H. O. Mayer, Lena Lisbeth Grimm, Jose Maria Orduña, Esben Trabjerg, Thilo Stehle, Kasper D. Rand, Bärbel S. Blaum, Charlotte Uetrecht, Thomas Peters   +11 more
doaj   +1 more source