Journal of Microbiology, Immunology and Infection, 2023 Background: Pseudomonas aeruginosa is not a common enteric pathogen. The association between human histo-blood group antigens (HBGAs) and P. aeruginosa enteric infection has not yet been studied.
Chih-Hsien Chuang +5 more
doaj +3 more sources
Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens. [PDF]
PLoS Pathogens, 2020 Initial cell attachment of rotavirus (RV) to specific cell surface glycan receptors, which is the essential first step in RV infection, is mediated by the VP8* domain of the spike protein VP4.
Shenyuan Xu +10 more
doaj +2 more sources
Norovirus binding to intestinal epithelial cells is independent of histo-blood group antigens. [PDF]
PLoS ONE, 2013 Human noroviruses (NoVs) are a major cause of non-bacterial gastroenteritis. Although histo-blood group antigens (HBGAs) have been implicated in the initial binding of NoV, the mechanism of that binding before internalization is not clear.
Kosuke Murakami +11 more
doaj +2 more sources
Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens. [PDF]
PLoS Pathogens, 2019 Rotavirus is the leading agent causing acute gastroenteritis in young children, with the P[8] genotype accounting for more than 80% of infections in humans.
Roberto Gozalbo-Rovira +8 more
doaj +2 more sources
Histo-blood group antigens: a common niche for norovirus and rotavirus. [PDF]
Expert Rev Mol Med, 2014 Noroviruses (NoVs) and rotaviruses (RVs), the two most important causes of viral acute gastroenteritis, are found to recognise histo-blood group antigens (HBGAs) as receptors or ligands for attachment. Human HBGAs are highly polymorphic containing ABO, secretor and Lewis antigens.
Tan M, Jiang X.
europepmc +3 more sources
Bovine Nebovirus Interacts with a Wide Spectrum of Histo-Blood Group Antigens. [PDF]
J Virol, 2018 ABSTRACT Some viruses within the Caliciviridae family initiate their replication cycle by attachment to cell surface carbohydrate moieties, histo-blood group antigens (HBGAs), and/or terminal sialic acids (SAs).
Cho EH +11 more
europepmc +3 more sources
Role of histo-blood group antigens in primate enteric calicivirus infections. [PDF]
World J Virol, 2014 Human noroviruses (NoV) are associated with large proportion of non-bacterial diarrhea outbreaks together with > 50% of food-associated diarrheas. The function of histo-blood group antigens (HBGAs) in pathogenesis of virus infection was implicated. Until recently however, due to lack of a robust animal and in vitro models of human NoV infection, only ...
Sestak K.
europepmc +3 more sources
Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides. [PDF]
J Virol, 2016 ABSTRACT Human noroviruses interact with both human histo-blood group antigens (HBGAs) and human milk oligosaccharides (HMOs). The former are believed to be important for a virus infection, while the latter might act as natural decoys in the host during an infection. However, certain noroviruses are known to bind poorly to HBGAs and yet still
Schroten H, Hanisch FG, Hansman GS.
europepmc +5 more sources
Attachment of Norovirus to Histo Blood Group Antigens: A Cooperative Multistep Process
Angewandte Chemie, 2015 AbstractHuman noroviruses recognize histo blood group antigens (HBGAs) as cellular attachment factors. Recently, it has been discovered that norovirus infection can be significantly enhanced by HBGA binding. Yet the attachment process and how it promotes host‐cell entry is only poorly understood.
Mallagaray, A +4 more
openaire +6 more sources
Affinities of human histo-blood group antigens for norovirus capsid protein complexes. [PDF]
Glycobiology, 2015 The binding profiles of many human noroviruses (huNoVs) for human histo-blood group antigens have been characterized. However, quantitative-binding data for these important virus–host interactions are lacking. Here, we report on the intrinsic (per binding site) affinities of HBGA oligosaccharides for the huNoV VA387 virus-like particles (VLPs) and the ...
Han L +6 more
europepmc +6 more sources