Structural analysis of histo-blood group antigen binding specificity in a norovirus GII.4 epidemic variant: implications for epochal evolution. [PDF]
J Virol, 2011 Susceptibility to norovirus (NoV), a major pathogen of epidemic gastroenteritis, is associated with histo-blood group antigens (HBGAs), which are also cell attachment factors for this virus.
Shanker S +5 more
europepmc +2 more sources
Human milk oligosaccharide 2'-fucosyllactose guards norovirus histo-blood group antigen co-factor binding site. [PDF]
J VirolRudd PA +7 more
europepmc +2 more sources
The alphaGal epitope of the histo-blood group antigen family is a ligand for bovine norovirus Newbury2 expected to prevent cross-species transmission. [PDF]
PLoS Pathogens, 2009 Among Caliciviridae, the norovirus genus encompasses enteric viruses that infect humans as well as several animal species, causing gastroenteritis. Porcine strains are classified together with human strains within genogroup II, whilst bovine norovirus ...
Maha Zakhour +7 more
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Biological and immunological characterization of major capsid protein VP1 from distinct GII.2 norovirus clusters [PDF]
Scientific ReportsHuman noroviruses (HuNoVs) are a leading cause of acute viral gastroenteritis worldwide. Infectious outbreaks due to recombinant NoV genotype called GII.P16-GII.2 have been frequently reported since 2016.
Jie Ma, Jinjin Liu, Yuqi Huo
doaj +2 more sources
Molecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region
Pathogens, 2021 Sapovirus is an important etiological agent of acute gastroenteritis (AGE), mainly in children under 5 years old living in lower-income communities. Eighteen identified sapovirus genotypes have been observed to infect humans. The aim of this study was to
Marcia Terezinha Baroni de Moraes +8 more
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Frontiers in Chemistry, 2021 The tandem-repeat Galectin-4 (Gal-4) contains two different domains covalently linked through a short flexible peptide. Both domains have been shown to bind preferentially to A and B histo blood group antigens with different affinities, although the ...
Jon I. Quintana +11 more
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Low Levels of Natural Anti-α-N-Acetylgalactosamine (Tn) Antibodies Are Associated With COVID-19
Frontiers in Microbiology, 2021 Human serum contains large amounts of anti-carbohydrate antibodies, some of which may recognize epitopes on viral glycans. Here, we tested the hypothesis that such antibodies may confer protection against COVID-19 so that patients would be preferentially
Adrien Breiman +14 more
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Viruses, 2020 Human norovirus (HuNoV) is the leading cause of global infectious acute gastroenteritis, causing ~20% of reported diarrheal episodes. Typically, GII.4 strains cause 50–70% of yearly outbreaks, and pandemic waves of disease approximately every 2–7 years ...
Michael L. Mallory +4 more
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Cancer Medicine, 2023 Background ABO blood groups has been associated with risk of several cancers; however, the results for an association with ovarian cancer are inconsistent and little is known about the expression of histo‐blood group (ABH) antigens and ABO gene in ...
Chao Wang +15 more
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Establishment and identification of a human megakaryocytic cell line with low Ley expression
Zhongguo shuxue zazhi, 2022 Objective To establish a stable human megakaryocytic cell line with low expression of Ley antigen to further study the role of Ley on activation of platelets.
Huijun ZHU +4 more
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