Results 41 to 50 of about 49,950 (108)

Extracellular Production of the Taiwan-Native Norovirus P Domain Overexpressed in Pichia pastoris

Fermentation, 2023
Many efforts in norovirus vaccine development have focused on subunit or recombinant protein vaccines, such as subviral P particles formed by the protruding (P) domain of VP1.
Man-Ling Chien, Chun-Fu Yu, Ching-Tsan Huang   +2 more
doaj   +1 more source

Human Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle Functionality

mSphere, 2016
Although two in vitro cultivation methods have been reported, discrimination of infectious human norovirus particles for study of viral inactivation is still a challenge, as both rely on reverse transcriptase quantitative PCR.
Matthew D. Moore, Benjamin G. Bobay, Brittany Mertens, Lee-Ann Jaykus   +3 more
doaj   +1 more source

Intestinal shedding of enteric agents in histo-blood group antigen-secretor children in an Australian community-based birth cohort study

Journal of Pediatric and Neonatal Individualized Medicine, 2022
Histo-blood group antigens are inherited polymorphic glycans expressed on mucosal epithelial cell surfaces and shed in secretions. They act as receptors for gastrointestinal pathogens. Those expressing these antigens are categorized as secretors and have
Gabor Mihala, Robert S. Ware, Catherine Cheung, Stephen B. Lambert, Peter D. Sly, David M. Whiley, Keith Grimwood   +6 more
doaj   +1 more source

Intestinal colonization with Escherichia fergusonii enhances infectivity of GII.12 human norovirus in gnotobiotic pigs

Virus Research, 2023
The role of gut microbiota [especially, histo-blood group antigen (HBGA)-expressing bacteria] in influencing human norovirus (HuNoV) infections is unclear.
Kwonil Jung, Qiuhong Wang, Kyeong-Ok Chang, Linda J. Saif   +3 more
doaj  

Possible Link Between the ABO Blood Group of Bioprosthesis Recipients and Specific Types of Structural Degeneration

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Pigs/bovines share common antigens with humans: α‐Gal, present in all pigs/bovines close to the human B‐antigen; and AH‐histo‐blood‐group antigen, identical to human AH‐antigen and present only in some animals.
Olivier Schussler, Nermine Lila, Juan Grau, Marc Ruel, Yves Lecarpentier, Alain Carpentier   +5 more
doaj   +1 more source

Lewis b antigen is a common ligand for genogroup I norovirus strains

FEBS Open Bio, 2022
Noroviruses are major causative agents of nonbacterial acute gastroenteritis in humans. Ten genogroups of noroviruses have been identified to date, among which genogroup I (GI) and genogroup II (GII) noroviruses are major pathogens for humans. GI and GII
Yuichi Someya
doaj   +1 more source

Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens.

PLoS Pathogens, 2019
Rotavirus is the leading agent causing acute gastroenteritis in young children, with the P[8] genotype accounting for more than 80% of infections in humans.
Roberto Gozalbo-Rovira, J Rafael Ciges-Tomas, Susana Vila-Vicent, Javier Buesa, Cristina Santiso-Bellón, Vicente Monedero, María J Yebra, Alberto Marina, Jesús Rodríguez-Díaz   +8 more
doaj   +1 more source

Binding Patterns of Rotavirus Genotypes P[4], P[6], and P[8] in China with Histo-Blood Group Antigens. [PDF]

PLoS ONE, 2015
Rotaviruses (RVs) are an important cause of severe gastroenteritis in children. It has been found that RV may recognize the histo-blood group antigens (HBGAs) as ligands or receptors and bind HBGAs in a type-dependent manner.
Xin Ma, Dan-di Li, Xiao-Man Sun, Yan-Qing Guo, Jing-Yao Xiang, Wei-Huan Wang, Li-Xia Zhang, Qing-Jiu Gu, Zhao-Jun Duan   +8 more
doaj   +1 more source

Clinical Significance of the Transcription Factor SOX11, Cell-Cell Adhesion Protein E-cadherin and Zinc Finger Protein BCL11A in the Diagnosis of Breast Cancer

Archives of Pharmaceutical Sciences Ain Shams University, 2021
Transcription factors (TFs) as SRY-Box transcription factor 11 (SOX11) and B-cell lymphoma/leukemia 11A (BCL11A) role in breast cancer (BC) as well as their effect on epithelial cadherin (E-cadherin) membrane protein which is a metastasis suppressor is a
Salma Salama, Nadia Hamdy, Reham El-Shimy, Hala El-Mesallamy   +3 more
doaj   +1 more source

Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding.

PLoS Pathogens, 2016
Noroviruses (NoV) are the most common cause of non-bacterial acute gastroenteritis and cause local outbreaks of illness, especially in confined situations.
Gopal Sapparapu, Rita Czakó, Gabriela Alvarado, Sreejesh Shanker, B V Venkataram Prasad, Robert L Atmar, Mary K Estes, James E Crowe   +7 more
doaj   +1 more source