A computational study of the statistical mechanics of antibody-antigen conformations [PDF]
We describe the representation of the chemical affinity between the antigen-combining site of the immunoglobulin molecule and the antigen molecule as the probability of the two molecules existing in a bound state. Our model is based on the identification of shape attractors in the configuration space for the joint antibody / antigen combining site ...
arxiv
Norovirus GII.17 Natural Infections in Rhesus Monkeys, China
Noroviruses are a leading viral cause of acute gastroenteritis among humans. During the 2014–15 epidemic season, norovirus GII.17 was detected in rhesus monkeys in China.
Zhanlong He+8 more
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A General Theory for Direct Quantitative Analysis of Antigen [PDF]
A theory for direct quantitative analysis of an antigen is proposed. It is based on a potential homogenous immunoreaction system. It establishes an equation to describe the concentration change of the antigen and antibody complex. A maximum point is found in the concentration profile of the complex which can be used to calculate the concentration of ...
arxiv
Norwalk virus binds to histo-blood group antigens present on gastroduodenal epithelial cells of secretor individuals [PDF]
Séverine Marionneau‐Lambot+8 more
openalex +1 more source
Noroviruses (NoV) are the most common cause of non-bacterial acute gastroenteritis and cause local outbreaks of illness, especially in confined situations.
Gopal Sapparapu+7 more
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Cloning and Expression of Human Norovirus GI.5 and GII.4 P Proteins and Their Binding Characteristics with Histo-Blood Group Antigens-like Substances in Pacific Oysters [PDF]
To clarify the binding characteristics of human norovirus (HuNoV) with histo-blood group antigens (HBGAs)-like substances from Pacific oysters, this study used an Escherichia coli expression system to clone and express HuNoV GI.5 and GII.4 P proteins ...
TONG Lihui, YANG Min, WANG Shanshan, WANG Dajun, WANG Mingli, ZHOU Deqing
doaj +1 more source
The use of quantum dots to amplify antigen detection [PDF]
Proposal to develop an Improved immunological assay employing primary IgG antibodies and secondary IgM antibodies labeled with quantum dots to amplify antigen detection.
arxiv
Canalization of the evolutionary trajectory of the human influenza virus [PDF]
Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic ladder-like genealogical tree. Here, we use a large-scale individual-based model to show that evolution in a Euclidean
arxiv
Histo-Blood Group Antigen and Human Milk Oligosaccharides [PDF]
Jacques Le Pendu
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Binding Patterns of Human Norovirus-Like Particles to Buccal and Intestinal Tissues of Gnotobiotic Pigs in Relation to A/H Histo-Blood Group Antigen Expression [PDF]
Sonia Cheetham+5 more
openalex +1 more source