Results 111 to 120 of about 17,546 (202)
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher +7 more
wiley +1 more source
A number of epidemiological studies have evaluated the potential association between H. pylori and cardiovascular disease, but with contrasting results.
Riccardo Negrini +3 more
doaj +1 more source
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne +4 more
wiley +1 more source
Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes [PDF]
The bacterial pathogen Helicobacter pylori commonly colonizes the human gastric mucosa during early childhood and persists throughout life. The organism has evolved multiple mechanisms for evading clearance by the immune system and, despite inducing ...
Robinson, K, White, JR, Winter, JA
core +1 more source
In an angiotensin‐II‐induced pressure overload induced heart failure mouse model, expression of MG23 is increased. Knockout of Mg23 protected hearts against Angiotensin‐II ‐induced cardiac hypertrophy. Mg23‐KO mice also displayed a marked decrease in left ventricular fibrosis and had normal cardiac functioning compared to wild type animals.
Amy M. Dorward +10 more
wiley +1 more source
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano +6 more
wiley +1 more source
Beyond the immune suppression: the immunotherapy in prostate cancer [PDF]
Prostate cancer (PCa) is the second most common cancer in men.Aswell in many other human cancers, inflammation and immune suppression have an important role in their development.We briefly describe the host components that interact with the tumor to ...
Agliano', Anna Maria +4 more
core +3 more sources
Cloning, Expression, and Functional Characterization of FUT1, a Key Gene for Histo-Blood Group Antigens Synthesis in Crassostrea gigas. [PDF]
Gui B +6 more
europepmc +1 more source
Influence of ABO genotype and phenotype on angiotensin-converting enzyme plasma activity [PDF]
ABO rs495828 polymorphism has recently been associated with risk of hypertension and cough induced by angiotensin-converting enzyme (ACE) inhibitors, which could be due to low ACE plasma activity.
Gassó Astorga, Patricia +3 more
core +1 more source
Canine liver transplantation under nva cyclosporine versus cyclosporine [PDF]
The immunosuppressive qualities and other features of a new cyclosporine (CsA) analogue, Nva 2-cyclosporine (Nva 2-CsA) were examined using canine orthotopic liver allografts.
DeWolf, A +6 more
core +1 more source

