Results 111 to 120 of about 17,546 (202)

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

open access: yesThe FEBS Journal, Volume 293, Issue 4, Page 1168-1190, February 2026.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher   +7 more
wiley   +1 more source

Anti-Glycan Autoantibodies Induced by Helicobacter pylori as a Potential Risk Factor for Myocardial Infarction

open access: yesFrontiers in Immunology, 2020
A number of epidemiological studies have evaluated the potential association between H. pylori and cardiovascular disease, but with contrasting results.
Riccardo Negrini   +3 more
doaj   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

open access: yesJournal of Fish Biology, Volume 108, Issue 2, Page 676-693, February 2026.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne   +4 more
wiley   +1 more source

Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes [PDF]

open access: yes, 2015
The bacterial pathogen Helicobacter pylori commonly colonizes the human gastric mucosa during early childhood and persists throughout life. The organism has evolved multiple mechanisms for evading clearance by the immune system and, despite inducing ...
Robinson, K, White, JR, Winter, JA
core   +1 more source

Knockout of the Intracellular Calcium Conducting Ion Channel Mitsugumin 23 (MG23) Protects Against Pressure Overload Induced Left Ventricular Hypertrophy and Cardiac Dysfunction

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
In an angiotensin‐II‐induced pressure overload induced heart failure mouse model, expression of MG23 is increased. Knockout of Mg23 protected hearts against Angiotensin‐II ‐induced cardiac hypertrophy. Mg23‐KO mice also displayed a marked decrease in left ventricular fibrosis and had normal cardiac functioning compared to wild type animals.
Amy M. Dorward   +10 more
wiley   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano   +6 more
wiley   +1 more source

Beyond the immune suppression: the immunotherapy in prostate cancer [PDF]

open access: yes, 2015
Prostate cancer (PCa) is the second most common cancer in men.Aswell in many other human cancers, inflammation and immune suppression have an important role in their development.We briefly describe the host components that interact with the tumor to ...
Agliano', Anna Maria   +4 more
core   +3 more sources

Influence of ABO genotype and phenotype on angiotensin-converting enzyme plasma activity [PDF]

open access: yes, 2017
ABO rs495828 polymorphism has recently been associated with risk of hypertension and cough induced by angiotensin-converting enzyme (ACE) inhibitors, which could be due to low ACE plasma activity.
Gassó Astorga, Patricia   +3 more
core   +1 more source

Canine liver transplantation under nva cyclosporine versus cyclosporine [PDF]

open access: yes, 1986
The immunosuppressive qualities and other features of a new cyclosporine (CsA) analogue, Nva 2-cyclosporine (Nva 2-CsA) were examined using canine orthotopic liver allografts.
DeWolf, A   +6 more
core   +1 more source

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