Results 91 to 100 of about 17,546 (202)
mBio, 2018 Emerging zoonotic viral diseases remain a challenge to global public health. Recent surveillance studies have implicated bats as potential reservoirs for a number of viral pathogens, including coronaviruses and Ebola viruses.
Jacob F. Kocher +10 more
doaj +1 more source
Viruses, 2022 Rotaviruses (RVs) are a significant cause of severe diarrheal illness in infants and young animals, including pigs. Group C rotavirus (RVC) is an emerging pathogen increasingly reported in pigs and humans worldwide, and is currently recognized as the ...
Yusheng Guo +5 more
doaj +1 more source
Histo-Blood Group Antigens: the Potential Receptor for the Rotaviruses [PDF]
SCIENTIA SINICA Vitae, 2015 Rotaviruses (RVs) are one of the most important pathogens for the viral gastroenteritis in human and animals. It is reported that histo-blood group antigens (HBGAs) may be the receptors and/or attachment factors for the RVs. HBGAs are highly polymorphic including ABO, secretor, and Lewis antigens.
ZhaoJun DUAN +3 more
openaire +1 more source
Arthritis &Rheumatology, Volume 78, Issue 4, Page 880-895, April 2026.Objective Systemic lupus erythematosus (SLE) is characterized by increased Type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama +16 more
wiley +1 more source
Norwalk Virus–specific Binding to Oyster Digestive Tissues
Emerging Infectious Diseases, 2006 The primary pathogens related to shellfishborne gastroenteritis outbreaks are noroviruses. These viruses show persistence in oysters, which suggests an active mechanism of virus concentration.
Françoise S. Le Guyader +7 more
doaj +1 more source
Duality of β-glucan microparticles: antigen carrier and immunostimulants [PDF]
, 2016 Designing efficient recombinant mucosal vaccines against enteric diseases is still a major challenge. Mucosal delivery of recombinant vaccines requires encapsulation in potent immunostimulatory particles to induce an efficient immune response. This paper
Baert, Kim +4 more
core +2 more sources
Brain and Behavior, Volume 16, Issue 4, April 2026.We find that loss of LRP1 in astrocytes improves long‐term outcomes after ischemic stroke and is associated with reduced gliosis. Our findings suggest a role for LRP1 in astrocyte reactivity and response to stroke. ABSTRACT Purpose Ischemic stroke is a primary cause of death and disability worldwide; however, therapeutic opportunities are limited ...
Meng Wang +4 more
wiley +1 more source
Glycan recognition in globally dominant human rotaviruses
Nature Communications, 2018 Human rotaviruses (RV) bind to histo-blood group antigens (HBGA) for attachment, but how different viral genotypes interact with HBGA isn’t known. Here, Hu et al. report crystal structures of a prevalent and a neonate-specific RV in complex with HBGA and
Liya Hu +13 more
doaj +1 more source
Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
, 2015 Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam +3 more
core +3 more sources
Norovirus Capture with Histo-Blood Group Antigens Reveals Novel Virus-Ligand Interactions [PDF]
Journal of Virology, 2004 ABSTRACT Noroviruses are genetically diverse, uncultivable, positive-sense RNA viruses and are the most common cause of epidemic acute gastroenteritis in humans in the United States. Recent studies of norovirus attachment in vitro by using recombinant virus-like particles (VLPs) suggest that various norovirus strains exhibit ...
Patrick R, Harrington +3 more
openaire +2 more sources