Results 71 to 80 of about 13,189,508 (152)
Histo-blood group antigens and rotavirus vaccine virus shedding in Australian infants
Rotavirus vaccine performance varies between high and low income countries. One possible explanation is inherited histo-blood group antigens (HBGAs) the expression of which differs between populations.
D M Whiley (13307013) +7 more
core
Norwalk Virus–specific Binding to Oyster Digestive Tissues
The primary pathogens related to shellfishborne gastroenteritis outbreaks are noroviruses. These viruses show persistence in oysters, which suggests an active mechanism of virus concentration.
Françoise S. Le Guyader +7 more
doaj +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Binding of Norwalk Virus-Like Particles to ABH Histo-Blood Group Antigens Is Blocked by Antisera from Infected Human Volunteers or Experimentally Vaccinated Mice [PDF]
specific ABH histo-blood group antigens was investigated by using human saliva and synthetic biotinylated carbohydrates. The three distinct Norwalk-like viruses (NLVs) have various capacities for binding ABH histo-blood group antigens, suggesting that ...
Lindesmith, L. +4 more
core +1 more source
Expression of histo-blood group antigens in vertebrate gonads
The tissue expression of human histo-blood group antigens (HBGA) in vertebrates, as well as their evolutionary tendencies and relation to histogenesis, especially in the reproductive system, are not entirely understood.The present research comprises a ...
Tomova, Elena +3 more
core +1 more source
Abstract Background Transfusion‐related alpha‐gal syndrome (TRAGS) has recently been proposed as a cause of allergic transfusion reactions (ATRs) in which alpha‐gal‐specific IgE in sensitized group O (or potentially group A) recipients reacts with epitopes on group B or AB plasma‐containing components.
Mackenzie Foster +9 more
wiley +1 more source
The suboptimal performance of rotavirus (RV) vaccines in developing countries and in animals necessitates further research on the development of novel therapeutics and control strategies.
Sergei A. Raev +5 more
doaj +1 more source
Glycan recognition in globally dominant human rotaviruses
Human rotaviruses (RV) bind to histo-blood group antigens (HBGA) for attachment, but how different viral genotypes interact with HBGA isn’t known. Here, Hu et al. report crystal structures of a prevalent and a neonate-specific RV in complex with HBGA and
Liya Hu +13 more
doaj +1 more source
Abstract Mirvetuximab‐soravtansine (MIRV‐S) is an antibody‐drug conjugate targeting folate receptor alpha (FOLR1). MIRV‐S is approved for the treatment of FOLR1‐positive, platinum‐resistant ovarian carcinoma. Patient eligibility is determined by immunohistochemistry (IHC) using a companion diagnostic (CDx) assay (FOLR1‐2.1, Ventana).
Annika Nasdala +10 more
wiley +1 more source

