Results 71 to 80 of about 13,139 (185)

Transfusion‐related alpha‐gal syndrome: Two new cases expanding the demographic and geographic spectrum, and evidence of a diagnostic gap in allergic transfusion reaction evaluation

Transfusion, Volume 66, Issue 6, Page 1167-1179, June 2026.
Abstract Background Transfusion‐related alpha‐gal syndrome (TRAGS) has recently been proposed as a cause of allergic transfusion reactions (ATRs) in which alpha‐gal‐specific IgE in sensitized group O (or potentially group A) recipients reacts with epitopes on group B or AB plasma‐containing components.
Mackenzie Foster, Miriam Brown, Angela Mueller, Toufik Tahiri, Kaycie Atchison, Deva Sharma, Cosby A. Stone Jr., Jonathan Tucci, Garrett S. Booth, Jeremy W. Jacobs   +9 more
wiley   +1 more source

Norovirus Infection and Disease in an Ecuadorian Birth Cohort: Association of Certain Norovirus Genotypes With Host FUT2 Secretor Status.

, 2015
BACKGROUND: Although norovirus is the most common cause of gastroenteritis, there are few data on the community incidence of infection/disease or the patterns of acquired immunity or innate resistance to norovirus.
Broncano, N, Vicuña, Y, Collins, N, Lopman, BA, Vaca, M, Chico, ME, Vinjé, J, Sandoval, C, Trivedi, T, Costantini, V, Parashar, U, Gregoricus, N, Cooper, PJ   +12 more
core   +1 more source

Rotavirus C Replication in Porcine Intestinal Enteroids Reveals Roles for Cellular Cholesterol and Sialic Acids

Viruses, 2022
Rotaviruses (RVs) are a significant cause of severe diarrheal illness in infants and young animals, including pigs. Group C rotavirus (RVC) is an emerging pathogen increasingly reported in pigs and humans worldwide, and is currently recognized as the ...
Yusheng Guo, Sergei Raev, Maryssa K. Kick, Molly Raque, Linda J. Saif, Anastasia N. Vlasova   +5 more
doaj   +1 more source

Reduced folate receptor alpha (FOLR1) protein expression in fallopian tubes from premenopausal women: implications for the FOLR1 CDx assay for mirvetuximab‐soravtansine therapy

The Journal of Pathology: Clinical Research, Volume 12, Issue 3, May 2026.
Abstract Mirvetuximab‐soravtansine (MIRV‐S) is an antibody‐drug conjugate targeting folate receptor alpha (FOLR1). MIRV‐S is approved for the treatment of FOLR1‐positive, platinum‐resistant ovarian carcinoma. Patient eligibility is determined by immunohistochemistry (IHC) using a companion diagnostic (CDx) assay (FOLR1‐2.1, Ventana).
Annika Nasdala, Leonie D Kandt, Martin Radner, Nora Schaumann, Malte Gronewold, Pia Hillmann, Henriette Christgen, Jens Hachenberg, Elna Kuehnle, Christian Hartmann, Matthias Christgen   +10 more
wiley   +1 more source

Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies

, 2023
Noroviruses are the leading cause of outbreaks of acute gastroenteritis. These viruses usually interact with histo-blood group antigens (HBGAs), which are considered essential cofactors for norovirus infection.
Marie Pancera, Kher, Gargi, Kerstin Ruoff, Devant, Jessica, Jennifer H. Lun, Mark von Itzstein, von Itzstein, Mark, Sabin, Charles, Koromyslova, Anna, Pancera, Marie, Charles Sabin, Anna D. Koromyslova, Gargi Kher, Lun, Jennifer, Ruoff, Kerstin, Grant S. Hansman, Hansman, Grant, Jessica M. Devant   +17 more
core   +1 more source

Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles

mBio, 2018
Emerging zoonotic viral diseases remain a challenge to global public health. Recent surveillance studies have implicated bats as potential reservoirs for a number of viral pathogens, including coronaviruses and Ebola viruses.
Jacob F. Kocher, Lisa C. Lindesmith, Kari Debbink, Anne Beall, Michael L. Mallory, Boyd L. Yount, Rachel L. Graham, Jeremy Huynh, J. Edward Gates, Eric F. Donaldson, Ralph S. Baric   +10 more
doaj   +1 more source

TYRO3, AXL, MERTK and Their Ligands in Brain Metastases From Colorectal Cancers

Cancer Medicine, Volume 15, Issue 5, May 2026.
TYRO3, AXL, and MERTK are expressed in primary tumors and extra‐cerebral and brain metastases from colorectal cancers. AXL, primarily expressed in endothelial cells, is the more conserved marker between primary tumor and brain metastasis. The Low AXL/High GAS6 ratio is of poor prognosis in metastatic colorectal cancer patients.
Anaïs Noblanc, Fatima Dkhissi, Pierre‐Olivier Guichet, Lucie Lebeau, Serge Milin, Sheik Emambux, Pauline Roussille, Camille Evrard, Lucie Karayan‐Tapon, David Tougeron, Omar Benzakour, Violaine Randrian   +11 more
wiley   +1 more source

Norwalk Virus–specific Binding to Oyster Digestive Tissues

Emerging Infectious Diseases, 2006
The primary pathogens related to shellfishborne gastroenteritis outbreaks are noroviruses. These viruses show persistence in oysters, which suggests an active mechanism of virus concentration.
Françoise S. Le Guyader, Fabienne Loisy, Robert L. Atmar, Anne M. Hutson, Mary K. Estes, Nathalie Ruvoën-Clouet, Monique Pommepuy, Jacques Le Pendu   +7 more
doaj   +1 more source

Binding Patterns of Rotavirus Genotypes P[4], P[6], and P[8] in China with Histo-Blood Group Antigens. [PDF]

PLoS One, 2015
Rotaviruses (RVs) are an important cause of severe gastroenteritis in children. It has been found that RV may recognize the histo-blood group antigens (HBGAs) as ligands or receptors and bind HBGAs in a type-dependent manner.
Ma X, Li DD, Sun XM, Guo YQ, Xiang JY, Wang WH, Zhang LX, Gu QJ, Duan ZJ.   +8 more
europepmc   +2 more sources

Glycan recognition in globally dominant human rotaviruses

Nature Communications, 2018
Human rotaviruses (RV) bind to histo-blood group antigens (HBGA) for attachment, but how different viral genotypes interact with HBGA isn’t known. Here, Hu et al. report crystal structures of a prevalent and a neonate-specific RV in complex with HBGA and
Liya Hu, Banumathi Sankaran, Daniel R. Laucirica, Ketki Patil, Wilhelm Salmen, Allan Chris M Ferreon, Phoebe S. Tsoi, Yi Lasanajak, David F. Smith, Sasirekha Ramani, Robert L. Atmar, Mary K. Estes, Josephine C. Ferreon, B. V. Venkataram Prasad   +13 more
doaj   +1 more source