Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies
Noroviruses are the leading cause of outbreaks of acute gastroenteritis. These viruses usually interact with histo-blood group antigens (HBGAs), which are considered essential cofactors for norovirus infection.
Marie Pancera +17 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
Wan‐Hua Yang, Fen‐Cing Liou
wiley +1 more source
Norovirus Gastroenteritis Outbreak with a Secretor-independent Susceptibility Pattern, Sweden
Norovirus (NoV) is recognized as the commonest cause of acute gastroenteritis among adults. Susceptibility to disease has been associated with histo-blood group antigens and secretor status; nonsecretors are almost completely resistant to disease.
Johan Nordgren +4 more
doaj +1 more source
Cloning, Expression, and Functional Characterization of FUT1, a Key Gene for Histo-Blood Group Antigens Synthesis in Crassostrea gigas. [PDF]
Gui B +6 more
europepmc +1 more source
Revisiting the role of histo-blood group antigens in rotavirus host-cell invasion
Histo-blood group antigens (HBGAs) have been proposed as rotavirus receptors. H type-1 and Lewisb antigens have been reported to bind VP8* from major human rotavirus genotypes P[4], P[6] and P[8], while VP8* from a rarer P[14] rotavirus recognizes A ...
Maggioni, Andrea +7 more
core +1 more source
Functional and structural characterization of Norovirus GII.6 in recognizing histo-blood group antigens. [PDF]
Cong X +7 more
europepmc +1 more source
ABO blood group antigens and preterm birth risk
BackgroundHost-vaginal-microbial interactions have been shown to influence spontaneous preterm birth (sPTB) risk(1,2). In other body niches, histo-blood group antigens are associated with microbiota composition and disease risk(3,4).ObjectiveTo ...
Dell, Anne +39 more
core +1 more source
Histo-Blood Group Antigens, Enteropathogen Carriage and Environmental Enteropathy in Stunted Zambian Children. [PDF]
Chandwe K +8 more
europepmc +1 more source
Histo-blood group epitopes are fucosylated branched oligosaccharides with well-defined conformations in solution that are recognized by receptors, such as lectins from pathogens.
Aymeric Audfray (447681) +20 more
core +1 more source
Cloning and Expression of Human Norovirus GI.5 and GII.4 P Proteins and Their Binding Characteristics with Histo-Blood Group Antigens-like Substances in Pacific Oysters [PDF]
To clarify the binding characteristics of human norovirus (HuNoV) with histo-blood group antigens (HBGAs)-like substances from Pacific oysters, this study used an Escherichia coli expression system to clone and express HuNoV GI.5 and GII.4 P proteins ...
TONG Lihui, YANG Min, WANG Shanshan, WANG Dajun, WANG Mingli, ZHOU Deqing
doaj +1 more source

