Results 81 to 90 of about 10,874,130 (155)

TYRO3, AXL, MERTK and Their Ligands in Brain Metastases From Colorectal Cancers

Cancer Medicine, Volume 15, Issue 5, May 2026.
TYRO3, AXL, and MERTK are expressed in primary tumors and extra‐cerebral and brain metastases from colorectal cancers. AXL, primarily expressed in endothelial cells, is the more conserved marker between primary tumor and brain metastasis. The Low AXL/High GAS6 ratio is of poor prognosis in metastatic colorectal cancer patients.
Anaïs Noblanc, Fatima Dkhissi, Pierre‐Olivier Guichet, Lucie Lebeau, Serge Milin, Sheik Emambux, Pauline Roussille, Camille Evrard, Lucie Karayan‐Tapon, David Tougeron, Omar Benzakour, Violaine Randrian   +11 more
wiley   +1 more source

Revealing and quantifying polyclonal anti‐A, B specificity in ABO histo‐blood groups

Transfusion, Volume 66, Issue 5, Page 965-975, May 2026.
Abstract Background The clinically significant antibody anti‐A,B together with anti‐A and anti‐B has been known for many decades to be present in blood group O plasma. As anti‐A,B is only reactive when an A or B antigen is present, its contribution to titer cannot be easily distinguished from anti‐A and/or anti‐B.
Stephen Henry, Holly Perry, Polina Obukhova, Tatiana Tyrtysh, Ivan Ryzhov, Nicolai Bovin, Suvro Sankha Datta   +6 more
wiley   +1 more source

Identification of Histone Deacetylase Inhibitor Targeting Type I Interferon and B Cell Abnormalities in Systemic Lupus Erythematosus

Arthritis &Rheumatology, Volume 78, Issue 4, Page 880-895, April 2026.
Objective Systemic lupus erythematosus (SLE) is characterized by increased Type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. [PDF]

, 2008
BACKGROUND: The asexual blood stages of the human malaria parasite Plasmodium falciparum produce highly immunogenic polymorphic antigens that are expressed on the surface of the host cell.
Christopher J. Drakeley, Saeed Maha, Saeed, Maha, Alexander Neal, Saeed, M., Geoffrey A T Targett, Sutherland, Colin J, Drakeley Christopher J., Targett Geoffrey A. T., Roeffen Will, Geoffrey A. T. Targett, Colin J. Sutherland, Targett, Geoffrey AT, Alexander, N., Neal Alexander, Colin J Sutherland, Sutherland Colin J., Targett, G.A.T., Roeffen, W.F.G., Roeffen, Will, Maha Saeed, Alexander, Neal, Drakeley, Christopher J, Drakeley, C., Will Roeffen, Christopher J Drakeley, Sutherland, C.J.   +26 more
core   +2 more sources

Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies

, 2023
Noroviruses are the leading cause of outbreaks of acute gastroenteritis. These viruses usually interact with histo-blood group antigens (HBGAs), which are considered essential cofactors for norovirus infection.
Marie Pancera, Kher, Gargi, Kerstin Ruoff, Devant, Jessica, Jennifer H. Lun, Mark von Itzstein, von Itzstein, Mark, Sabin, Charles, Koromyslova, Anna, Pancera, Marie, Charles Sabin, Anna D. Koromyslova, Gargi Kher, Lun, Jennifer, Ruoff, Kerstin, Grant S. Hansman, Hansman, Grant, Jessica M. Devant   +17 more
core   +1 more source

Cloning, Expression, and Functional Characterization of FUT1, a Key Gene for Histo-Blood Group Antigens Synthesis in Crassostrea gigas. [PDF]

Curr Issues Mol Biol, 2023
Gui B, Yao L, Qu M, Zhang W, Li M, Jiang Y, Wang L.   +6 more
europepmc   +1 more source

Human milk oligosaccharide 2′-fucosyllactose guards norovirus histo-blood group antigen co-factor binding site

Histo-blood group antigens (HBGAs) are critical polymorphic glycan co-factors required for most norovirus infections (1, 2). However, human milk oligosaccharide (HMO) 2’-fucosyllactose (2’-FL), a component of human breast milk and made up of related ...
Irie, Hiro, Kher, Gargi, Haselhorst, Thomas, Tame, Jeremy RH, von Itzstein, Mark, Rudd, Penny A, Hansman, Grant S, Pancera, Marie   +7 more
core   +1 more source

Revisiting the role of histo-blood group antigens in rotavirus host-cell invasion

, 2015
Histo-blood group antigens (HBGAs) have been proposed as rotavirus receptors. H type-1 and Lewisb antigens have been reported to bind VP8* from major human rotavirus genotypes P[4], P[6] and P[8], while VP8* from a rarer P[14] rotavirus recognizes A ...
Maggioni, Andrea, Haselhorst, Thomas, Dang, Vi T, E. Fleming, Fiona, von Itzstein, Mark, Fleming, Fiona E, Coulson, Barbara S, Boehm, Raphael, Holloway, Gavan, S. Coulson, Barbara, Bohm, Raphael, T. Dang, Vi   +11 more
core   +1 more source

Binding of Escherichia coli Does Not Protect Tulane Virus from Heat-Inactivation Regardless the Expression of HBGA-Like Molecules

Frontiers in Microbiology, 2017
Histo-blood group antigens (HBGAs) are considered as receptors/co-receptors for human norovirus (HuNoV). It has been reported that binding of HuNoV-derived virus-like particles (VLPs) to HBGA-like molecules-expressing bacteria increased the stability of ...
Qianqian Li, Qianqian Li, Dapeng Wang, David Yang, Lei Shan, Peng Tian   +5 more
doaj   +1 more source

Functional and structural characterization of Norovirus GII.6 in recognizing histo-blood group antigens. [PDF]

Virol Sin, 2023
Cong X, Li HB, Sun XM, Qi JX, Zhang Q, Duan ZJ, Xu Y, Liu WL.   +7 more
europepmc   +1 more source