Results 291 to 300 of about 335,757 (388)

Primary structure of murine major histocompatibility complex alloantigens: isolation, biochemical characterization, and preliminary alignment of CNBr fragments from the H-2Ib glycoprotein.

, 1978
Bruce M. Ewenstein, T Nisizawa, Hiroshi Uehara, S.G. Nathenson, J E Coligan, Thomas J. Kindt   +5 more
openalex   +1 more source

Massive Sampling Strategy for Antibody–Antigen Targets in CAPRI Round 55 With MassiveFold

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Massive sampling with AlphaFold2 improves protein–protein complex predictions. This has been shown during the last CASP15‐CAPRI blind prediction round by the AFsample tool. However, more difficult targets including antibody–antigen binding remain challenging. CAPRI Round 55 consisted of three antibody–antigen targets and one heterotrimer.
Nessim Raouraoua, Marc F. Lensink, Guillaume Brysbaert   +2 more
wiley   +1 more source

From genetic variants to therapeutic targets: insights into understanding rheumatoid arthritis. [PDF]

Front Immunol
Chen L, Zhao J, Meng Q.
europepmc   +1 more source

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

Error in Author Affiliation.

JAMA Dermatol
europepmc   +1 more source

Genome-Wide Meta-Analysis Identifies Five Single-Nucleotide Polymorphisms Associated With Both Vitiligo and Freckles in the Chinese Han Population. [PDF]

J Cosmet Dermatol
Lu J, Wang Y, Li Z, Yu J, Song C, Wang M, Yan S, Du J, Liu C, Guo X, Feng X, Niu W, Lv M, Chen W, Han Y, Zhen Q, Sun L.   +16 more
europepmc   +1 more source

Rationalizing Enhanced Affinity of Engineered T‐Cell Receptors in Cancer Immunotherapy Through Interaction Energy Calculations and Residue Correlation Analysis

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The advancement of T cell engineering has significantly transformed the field of cancer immunotherapy. In particular, T cells equipped with modified T cell receptors present a promising therapeutic strategy, especially for addressing solid tumors.
Mario Frezzini, Daniele Narzi
wiley   +1 more source

Implications and Considerations Concerning the Status, Habitat and Distribution of the Least Brook Lamprey, Lampetra aepyptera (Abbott) (Pisces: Petromyzontidae) in Arkansas [PDF]

, 1980
Carter, F. Allen, McAllister, Chris T., Sewell, Stephen A.   +2 more
core   +2 more sources

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source