Results 1 to 10 of about 289,641 (264)

Human leukocyte antigen-G in solid tumors: from immunotolerance to immunotherapy [PDF]

Frontiers in Immunology
Immune checkpoint-targeted immunotherapy has achieved unprecedented success, yet its limitations remain evident. Human leukocyte antigen-G (HLA-G), a novel immune checkpoint, exhibits restricted physiologic expression but is broadly expressed in various ...
Aifen Lin, Aifen Lin, Aifen Lin, Wei-Hua Yan, Wei-Hua Yan, Wei-Hua Yan   +5 more
doaj   +2 more sources

Effect of preexisting human leukocyte antigen donor-specific antibodies especially human leukocyte antigen-DQ on kidney transplant outcome [PDF]

Frontiers in Nephrology
BackgroundAnti-HLA-DQ donor-specific antibodies are increasingly recognized for their role in early rejection and compromised graft function following kidney transplantation.MethodsA total of 119 prospective kidney transplant recipients were evaluated ...
Sonia Mehrotra, Raj Kumar Sharma, Rakesh Kapoor, Rajesh Kumar Jaiswal, Rohit Kapoor   +4 more
doaj   +2 more sources

Evaluation of ascitic soluble human leukocyte antigen-G for distinguishing malignant ascites from benign ascites

Tumor Biology, 2017
The overexpression of soluble human leukocyte antigen-G is associated with malignant tumours. The purpose of our study was to detect soluble human leukocyte antigen-G concentrations in ascites and to evaluate the value of ascitic soluble human leukocyte ...
Juan Sun, Yan-Xiang Chang, Chun-Yan Niu
doaj   +2 more sources

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

Frontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang, Jielin Wang, Xuan You, Xuan You, Yanmin He, Yanmin He, Xiaozhen Hong, Xiaozhen Hong, Ji He, Ji He, Sudan Tao, Sudan Tao, Faming Zhu, Faming Zhu   +13 more
doaj   +1 more source

Human leukocyte antigen-A, B, and DRB1 diversity in renal transplant patients and donors: A single-center retrospective observational study

Indian Journal of Transplantation, 2022
Background: The understanding of transplant acceptance or rejection derives directly from knowing human leukocyte antigen (HLA) involved in the immune response.
Vikash Chandra Mishra, Dinesh Chandra, Trupti Deshpande, Parvind Singh, Archana Anthwal, Vimarsh Raina   +5 more
doaj   +1 more source

Frequency of class 1 human leukocyte antigen allele subtypes in Egyptian patients with idiopathic uveitis

Journal of the Egyptian Ophthalmological Society, 2023
Bacground Idiopathic uveitis is the most common uveitis type and is viewed as an inconclusive diagnosis for patients as well as physicians. Human leukocyte antigen (HLA) typing helps in understanding the pathogenesis of several diseases.
Dina M.R Bahgat, Alaa A Gad, Walid R Kosmass, Mariam R Fadel, Fatma H Abdelraouf   +4 more
doaj   +1 more source

Early Blood Transfusion After Kidney Transplantation Does Not Lead to dnDSA Development: The BloodIm Study

Frontiers in Immunology, 2022
Outcomes after kidney transplantation are largely driven by the development of de novo donor-specific antibodies (dnDSA), which may be triggered by blood transfusion.
Thomas Jouve, Thomas Jouve, Johan Noble, Johan Noble, Hamza Naciri-Bennani, Céline Dard, Dominique Masson, Gaëlle Fiard, Gaëlle Fiard, Paolo Malvezzi, Lionel Rostaing, Lionel Rostaing   +11 more
doaj   +1 more source

Human leukocyte antigen-B alleles in spondyloarthritides: A single-center, prospective, cross-sectional study

Indian Journal of Rheumatology, 2022
Objective: The objective of this study is to study distribution of human leukocyte antigen (HLA)-B alleles in Spondyloarthritis (SpA) and to find its clinical relevance in the patient management.
Jeet Hemantkumar Patel, Ved Chaturvedi, Lalit Duggal, Neeraj Jain, Gurbir Bhandari, Monika Jain   +5 more
doaj   +1 more source

Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia

Haematologica, 2020
Human leukocyte antigen-G is a non-classical major histocompatibility complex class I antigen with potent immune-inhibitory function. Human leukocyte antigen-G benefit patients in allotransplantation and autoimmune diseases by interacting with its ...
Xin Li, Zi Sheng, Yuanxin Sun, Yuanjian Wang, Miao Xu, Zhiyue Zhang, Hui Li, Linlin Shao, Yanqi Zhang, Jinming Yu, Chunhong Ma, Chengjiang Gao, Ming Hou, Heyu Ni, Jun Peng, Ji Ma, Qi Feng   +16 more
doaj   +1 more source

Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]

Medicinski Glasnik, 2023
Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić, Velma Selmanović, Sniježana Hasanbegović, Nedim Begić, Emina Karčić, Elma Fejzić   +5 more
doaj   +1 more source