Results 21 to 30 of about 8,336,904 (303)

Focal adhesion kinase mediates human leukocyte histocompatibility antigen class II-induced signaling in gingival fibroblasts [PDF]

, 2007
Background and Objective: The role of human leukocyte antigen class II molecules on nonantigen-presenting cells has been a matter of controversy. We previously reported that human leukocyte antigen class II molecules on human gingival fibroblasts do not ...
Yoshizawa, S., Ohyama, H., Takeuchi-Hatanaka, K., Matsushita, S., Meguro, M., Takashiba, S., Nishimura, Fusanori   +6 more
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Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]

Medicinski Glasnik, 2023
Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić, Velma Selmanović, Sniježana Hasanbegović, Nedim Begić, Emina Karčić, Elma Fejzić   +5 more
doaj   +1 more source

The puzzling relationship between human leukocyte antigen HLA genes and celiac disease [PDF]

, 2018
The human leukocyte antigen (HLA) system, i.e., the major histocompatibility complex (MHC) in humans, plays a pivotal role in the antigen presentation of intracellular and extracellular peptides and the regulation of innate and adaptive immune ...
Catassi C., Carlo Catassi, Catassi Giulia Naspi, Giulia Naspi Catassi, Catassi G. N., Catassi Carlo   +5 more
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HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy [PDF]

, 2008
We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258
Battegay, Manuel, Günthard, Huldrych F, Gaudieri, S., Swiss, HIV Cohort Study, John, Mina, Nolan, David, James, Ian, Furrer, H, Schmid, P, Battegay, M., McKinnon, E, Rauch, A., Swiss HIV Cohort Study, ., McKinnon, E., Telenti, A, Günthard, Huldrych F., Schmid, Patrick, Rauch, A, John, M., James, I, Furrer, Hansjakob, Hirschel, Bernard, Telenti, Amalio, Schmid, P., Furrer, H., Rauch, Andri, John, M, Günthard, H.F., Mallal, Simon, Telenti, A., McKinnon, Elizabeth, Nolan, D., Günthard, H F, Hirschel, B, Günthard, H. F., Battegay, M, Hirschel, B., Nolan, D, Mallal, S, James, I., Gaudieri, Silvana, Mallal, S., Gaudieri, S, John M, Battegay M, James I, Nolan D, Gaudieri S, Rauch A, Mallal S, Schmid P, Telenti A, Furrer H, McKinnon E, Hirschel B, Günthard HF   +55 more
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Human Leukocyte Antigen (HLA) [PDF]

, 2019
This book is a concise review of medically important applications of Human Leukocyte Antigen (HLA) in medicine. It covers both basic knowledge of HLA and its main clinical applications in medical practice.

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Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry [PDF]

, 2021
Background and Aims Genetic predisposition to autoimmune hepatitis (AIH) in adults is associated with possession of human leukocyte antigen (HLA) class I (A*01, B*08) and class II (DRB1*03, ‐04, ‐07, or ‐13) alleles, depending on geographic region ...
Longhi, Maria Serena, Samyn, Marianne, Wong, Guan-Wee, Yang, Li, Graham, Jonathon, Ma, Yun, Zen, Yoh, Mieli-Vergani, Giorgina, McPhail, Mark J., Quaglia, Alberto, Wang, Pengyun, Thompson, Richard J., Hadzic, Nedim, Heneghan, Michael A., Bansal, Sanjay, Vergani, Diego, Su, Haibin, Yuksel, Muhammed, Doherty, Derek G.   +18 more
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HLA Class I (A and B) Allele Polymorphism in a Moroccan Population Infected with Hepatitis C Virus

Current Issues in Molecular Biology
Hepatitis C virus (HCV) infection is one of the major health burdens worldwide. Its course depends on the virus itself and the host’s immune responses.
Safa Machraoui, Abdelmalek Hakmaoui, Khaoula Errafii, Mehdi Knidiri, Lamiaa Essaadouni, Khadija Krati, Brahim Admou   +6 more
doaj   +1 more source

Position 156 influences the peptide repertoire and tapasin dependency of human leukocyte antigen B*44 allotypes

Haematologica, 2012
Background Polymorphic differences between donor and recipient human leukocyte antigen class I molecules can result in graft-versus-host disease due to distinct peptide presentation. As part of the peptide-loading complex, tapasin plays an important role
Soumya Badrinath, Philippa Saunders, Trevor Huyton, Susanne Aufderbeck, Oliver Hiller, Rainer Blasczyk, Christina Bade-Doeding   +6 more
doaj   +1 more source

Improving Access to HLA-Matched Kidney Transplants for African American Patients

Frontiers in Immunology, 2022
IntroductionKidney transplants fail more often in Black than in non-Black (White, non-Black Hispanic, and Asian) recipients. We used the estimated physicochemical immunogenicity for polymorphic amino acids of donor/recipient HLAs to select weakly ...
Dulat Bekbolsynov, Beata Mierzejewska, Sadik Khuder, Obinna Ekwenna, Michael Rees, Michael Rees, Michael Rees, Robert C. Green, Stanislaw M. Stepkowski   +8 more
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Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms [PDF]

, 2005
Integrins are adhesion receptors that are crucial to the functions of multicellular organisms. Integrin-mediated adhesion is a complex process that involves both affinity regulation and cytoskeletal coupling, but the molecular mechanisms behind this ...
Susanna C. Fagerholm, Fagerholm, Susanna C., Nurmi, SM, Hilden, Tiina J., Gahmberg, CG, Gahmberg, Carl G., Carl G. Gahmberg, Susanna M. Nurmi, Nurmi, Susanna M., Fagerholm, SC, Tiina J. Hilden, Hilden, TJ   +11 more
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