Results 41 to 50 of about 8,336,904 (303)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Supplementary_Files_191125 – Supplemental material for Human leukocyte antigen DRB1*04:05 and clozapine-induced agranulocytosis/granulocytopenia

, 2020
Supplemental material, Supplementary_Files_191125 for Human leukocyte antigen DRB1*04:05 and clozapine-induced agranulocytosis/granulocytopenia by Takeo Saito, Masashi Ikeda, Taisei Mushiroda and Nakao Iwata in Australian & New Zealand Journal of ...
Masashi Ikeda (162465), Nakao Iwata (139930), Taisei Mushiroda (132414), Takeo Saito (445008)   +3 more
core   +1 more source

Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]

, 1997
Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Pieters, J., Watts, Colin, Knight, Andrew M., Colin Watts, Ferrari, Giorgio, Andrew M. Knight, Pieters, Jean, Ferrari, G., Watts, C., Jean Pieters, Giorgio Ferrari, Knight, A. M.   +11 more
core   +1 more source

False-positive reactivity of anti-human leukocyte antigen antibodies detected using the single-antigen bead assay

, 2021
The single-antigen bead assay (SABA) demonstrates high sensitivity and specificity for detecting anti-human leukocyte antigen (HLA) antibodies. However, SABA may produce false-positive results for anti-HLA antibodies.
김신영, 박윤희, 김보연, 김현숙, Boyeon Kim, Sinyoung Kim, Younhee Park, Hyon-Suk Kim   +7 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Analysis of Human Leukocyte Antigen Frequency among Renal Transplant Recipients and Donors in Nepal

Global Journal of Transfusion Medicine
Background and Objectives: Kidney transplants are effective for advanced renal failure, but graft rejection can occur when the recipient’s immune system misidentifies the kidney as a foreign object.
Rekha Manandhar, Gaurab Pandey, Ranjan Raj Bhatta, Runa Jha   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Highly sensitized kidney transplant candidates: integrating acceptable mismatch, desensitization, imlifidase, and emerging immune-cell targeting strategies

Frontiers in Immunology
Highly sensitized kidney transplant candidates are difficult to transplant because anti-human leukocyte antigen (HLA) sensitization restricts access to immunologically compatible organs, as transplantation across donor-specific antibodies (DSA) increases
Stefan Reuter, Nils Lachmann, Hans de Ferrante, Georg A. Böhmig, Klemens Budde   +4 more
doaj   +1 more source

Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank

, 2022
Supplementary methods, results, figures and tables for the manuscript "Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank" by Fawcett et ...
Stephan Ossowski (8902298), German Demidov (12126402), Megan L Paynton (12126407), Ed Hollox (10059910), Katherine Fawcett (8688516), Nick Shrine (8711865), Ian Sayers (37266), Louise Wain (8712140)   +7 more
core   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source