Results 11 to 20 of about 291,154 (262)

Human Leukocyte Antigens in Pregnancy and Preeclampsia [PDF]

Frontiers in Genetics, 2022
Preeclampsia is a pregnancy-induced hypertensive disorder, the pathophysiology of which includes underlying maternal cardiovascular disease, deficient spiral artery remodeling during placenta development, and inflammatory immune responses at the maternal-fetal interface.
Aisagbonhi, Omonigho, Morris, Gerald P
openaire   +4 more sources

Human leukocyte antigen B27 [PDF]

Clinical Medicine, 2010
The year 1973 was quite an eventful one with key important milestones occurring in the political and scientific domains. It was the year when American troops finally withdrew from Vietnam, Pink Floyd released Dark side of the moon , and the UK joined the European Economic Community.
openaire   +2 more sources

Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]

Medicinski Glasnik, 2023
Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić, Velma Selmanović, Sniježana Hasanbegović, Nedim Begić, Emina Karčić, Elma Fejzić   +5 more
doaj   +1 more source

HLA Class I (A and B) Allele Polymorphism in a Moroccan Population Infected with Hepatitis C Virus

Current Issues in Molecular Biology
Hepatitis C virus (HCV) infection is one of the major health burdens worldwide. Its course depends on the virus itself and the host’s immune responses.
Safa Machraoui, Abdelmalek Hakmaoui, Khaoula Errafii, Mehdi Knidiri, Lamiaa Essaadouni, Khadija Krati, Brahim Admou   +6 more
doaj   +1 more source

Position 156 influences the peptide repertoire and tapasin dependency of human leukocyte antigen B*44 allotypes

Haematologica, 2012
Background Polymorphic differences between donor and recipient human leukocyte antigen class I molecules can result in graft-versus-host disease due to distinct peptide presentation. As part of the peptide-loading complex, tapasin plays an important role
Soumya Badrinath, Philippa Saunders, Trevor Huyton, Susanne Aufderbeck, Oliver Hiller, Rainer Blasczyk, Christina Bade-Doeding   +6 more
doaj   +1 more source

Improving Access to HLA-Matched Kidney Transplants for African American Patients

Frontiers in Immunology, 2022
IntroductionKidney transplants fail more often in Black than in non-Black (White, non-Black Hispanic, and Asian) recipients. We used the estimated physicochemical immunogenicity for polymorphic amino acids of donor/recipient HLAs to select weakly ...
Dulat Bekbolsynov, Beata Mierzejewska, Sadik Khuder, Obinna Ekwenna, Michael Rees, Michael Rees, Michael Rees, Robert C. Green, Stanislaw M. Stepkowski   +8 more
doaj   +1 more source

Cytokine profile in COVID-19 infection: focus on interleukin-13, interleukin-33, and tumor necrosis factor-α as immunological markers

Italian Journal of Medicine
COVID-19 is a pandemic disease that has a wide spectrum of symptoms from asymptomatic to severe fatal cases due to hyperactivation of the immune system and secretion of pro-inflammatory cytokines.
Huda Saleem, Wafaa Hazim, Batool Mutar Mahdi, Mohammed S. Al-Iedani   +3 more
doaj   +1 more source

Human leukocyte antigen-G isoform HLA-G2/6, but not HLA-G1/4/5, is an independent indicator of poor survival in patients with colorectal cancer

Frontiers in Immunology
BackgroundHuman leukocyte antigen (HLA)-G has multiple isoforms with unique molecular structures and receptor-binding specificities. Different HLA-G isoform(s) may have distinct clinical relevance.
Xia Zhang, Xia Zhang, Qiu-Yue Han, Qiu-Yue Han, Jian-Gang Zhang, Jiao Lin, Wei-Hua Yan, Wei-Hua Yan, Wei-Hua Yan, Aifen Lin, Aifen Lin, Aifen Lin   +11 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The human leukocyte antigen system … simplified

Global Journal of Transfusion Medicine, 2017
Human leukocyte antigen (HLA) and transfusion medicine go hand in hand. Transfusion medicine experts are involved in transplants, particularly hematopoietic stem cell transplant.
Anand Deshpande
doaj   +1 more source