Results 21 to 30 of about 5,283 (169)
In the present study, we have done an acute toxicological experiment on the rat liver by administration of SVATE-3 in clinical doses (high and low dose, respectively) for 3 weeks. By using morphological methods, light and electron microscopy, enzyme histocytochemistry in light and electron microscope and biochemistry, we have observed the histological ...
Yuxiu Shi +9 more
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The basic knowledge of treating clinicopathological features is essential for analysis. In this note, we describe procedures for the analysis of clinicopathological features, with a focus on statistics.
Ichiro Akagi +3 more
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2. Histocytochemistry Series In Situ Hybridization Using Non-radioisotope labeled RNA Probes (4)
In situ hybridization is a powerful method directed toward obtaining spatial and temporal information concerning the expression and distribution of RNA molecules (e.g., messenger RNA and microRNA) in vivo. In this technical note, we describe procedures for in situ hybridization with non-radioisotope labeled RNA probes, especially a digoxigenin-labeled ...
Takuya Mishima +3 more
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The confocal laser scanning microscope (CLSM) is a device for obtaining high-resolution optical images of immunofluorescent staining. The CLSM can produce in-focus images of thick specimens, a process known as optical sectioning. The images are reconstructed with a computer, using 3-dimensional image software, allowing 3-dimensional reconstructions of ...
Zenya Naito
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2. Histocytochemistry Series Immunohistochemistry in Pathology (5)
Immunohistochemistry is a technique to examine the expression and distribution of biomolecules in situ using antibodies labeled with enzymes, such as horseradish peroxidase. Generally, both immunohistochemistry and immunofluorescence are termed as immunostaining, because localized biomolecules in situ are detected with antigen-antibody immunoreactions ...
Akira Shimizu +3 more
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Histochemistry, especially immunohistochemistry, is a powerful and diverse set of methods for obtaining spatial and temporal information concerning the expression and distribution of biomolecules in situ. In this technical note, we describe procedures for fixation and immunofluorescence microscopy using cryostat sections.
Toshihiro Takizawa
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2. Histocytochemistry Series A New Antigen Retrieval Method (6)
Current antigen retrieval techniques include the use of citrate buffer, Tris-HCl containing 5% urea, and EDTA solutions combined with heating in a microwave oven or autoclave. These methods must be adjusted for a given tissue or antigen. To improve the efficiency of antigen retrieval for immunohistochemical staining, we developed a new method using ...
Shigeki Namimatsu +2 more
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Imunopatogenetski mehanizmi nastanka i razvoja hroničnih zubnih periapeksnih lezija [PDF]
Lukić Aleksandra M. +2 more
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Performance of externally validated machine learning models based on histopathology images for the diagnosis, classification, prognosis, or treatment outcome prediction in female breast cancer: A systematic review. [PDF]
Numerous machine learning (ML) models have been developed for breast cancer using various types of data. Successful external validation (EV) of ML models is important evidence of their generalizability. The aim of this systematic review was to assess the
Gonzalez R +5 more
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Hyaluronic Acid (HA) Receptors and the Motility of Schwann Cell(-Like) Phenotypes. [PDF]
The cluster of differentiation 44 (CD44) and the hyaluronan-mediated motility receptor (RHAMM), also known as CD168, are perhaps the most studied receptors for hyaluronic acid (HA); among their various functions, both are known to play a role in the ...
Ouasti S +5 more
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