Results 21 to 30 of about 5,283 (169)

Experimental study for the toxicological effects of SVATE-3 on rat liver. Observation by light and electron microscope and by enzyme histocytochemistry.

open access: bronzeACTA HISTOCHEMICA ET CYTOCHEMICA, 1990
In the present study, we have done an acute toxicological experiment on the rat liver by administration of SVATE-3 in clinical doses (high and low dose, respectively) for 3 weeks. By using morphological methods, light and electron microscopy, enzyme histocytochemistry in light and electron microscope and biochemistry, we have observed the histological ...
Yuxiu Shi   +9 more
openalex   +4 more sources

2. Histocytochemistry Series The Basic Knowledge for the Analysis of Clinicopathological Features (7)

open access: bronzeNihon Ika Daigaku Igakkai Zasshi, 2011
The basic knowledge of treating clinicopathological features is essential for analysis. In this note, we describe procedures for the analysis of clinicopathological features, with a focus on statistics.
Ichiro Akagi   +3 more
openalex   +4 more sources

2. Histocytochemistry Series In Situ Hybridization Using Non-radioisotope labeled RNA Probes (4)

open access: bronzeNihon Ika Daigaku Igakkai Zasshi, 2010
In situ hybridization is a powerful method directed toward obtaining spatial and temporal information concerning the expression and distribution of RNA molecules (e.g., messenger RNA and microRNA) in vivo. In this technical note, we describe procedures for in situ hybridization with non-radioisotope labeled RNA probes, especially a digoxigenin-labeled ...
Takuya Mishima   +3 more
openalex   +3 more sources

2. Histocytochemistry Series Morphological and Functional Analyses of Cells, Using Confocal Laser Scanning Microscopy System: Example for Morphological and Functional Analyses of Cancer Cells, Using Multi-mode Microscopy System (2)

open access: bronzeNihon Ika Daigaku Igakkai Zasshi, 2009
The confocal laser scanning microscope (CLSM) is a device for obtaining high-resolution optical images of immunofluorescent staining. The CLSM can produce in-focus images of thick specimens, a process known as optical sectioning. The images are reconstructed with a computer, using 3-dimensional image software, allowing 3-dimensional reconstructions of ...
Zenya Naito
openalex   +4 more sources

2. Histocytochemistry Series Immunohistochemistry in Pathology (5)

open access: bronzeNihon Ika Daigaku Igakkai Zasshi, 2010
Immunohistochemistry is a technique to examine the expression and distribution of biomolecules in situ using antibodies labeled with enzymes, such as horseradish peroxidase. Generally, both immunohistochemistry and immunofluorescence are termed as immunostaining, because localized biomolecules in situ are detected with antigen-antibody immunoreactions ...
Akira Shimizu   +3 more
openalex   +3 more sources

2. Histocytochemistry Series Light Microscopic Immunohistochemistry: Fixation and Immunofluorescence Microscopy Using Cryostat-sections (1)

open access: bronzeNihon Ika Daigaku Igakkai Zasshi, 2009
Histochemistry, especially immunohistochemistry, is a powerful and diverse set of methods for obtaining spatial and temporal information concerning the expression and distribution of biomolecules in situ. In this technical note, we describe procedures for fixation and immunofluorescence microscopy using cryostat sections.
Toshihiro Takizawa
openalex   +4 more sources

2. Histocytochemistry Series A New Antigen Retrieval Method (6)

open access: bronzeNihon Ika Daigaku Igakkai Zasshi, 2010
Current antigen retrieval techniques include the use of citrate buffer, Tris-HCl containing 5% urea, and EDTA solutions combined with heating in a microwave oven or autoclave. These methods must be adjusted for a given tissue or antigen. To improve the efficiency of antigen retrieval for immunohistochemical staining, we developed a new method using ...
Shigeki Namimatsu   +2 more
openalex   +4 more sources

Performance of externally validated machine learning models based on histopathology images for the diagnosis, classification, prognosis, or treatment outcome prediction in female breast cancer: A systematic review. [PDF]

open access: yesJ Pathol Inform, 2023
Numerous machine learning (ML) models have been developed for breast cancer using various types of data. Successful external validation (EV) of ML models is important evidence of their generalizability. The aim of this systematic review was to assess the
Gonzalez R   +5 more
europepmc   +2 more sources

Hyaluronic Acid (HA) Receptors and the Motility of Schwann Cell(-Like) Phenotypes. [PDF]

open access: yesCells, 2020
The cluster of differentiation 44 (CD44) and the hyaluronan-mediated motility receptor (RHAMM), also known as CD168, are perhaps the most studied receptors for hyaluronic acid (HA); among their various functions, both are known to play a role in the ...
Ouasti S   +5 more
europepmc   +3 more sources

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