Results 11 to 20 of about 33,964 (160)

Coxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCK [PDF]

, 2015
The GTPases belonging to the Rho family control the actin cytoskeleton rearrangements needed for particle internalization during phagocytosis. ROCK and mDia1 are downstream effectors of RhoA, a GTPase involved in that process.
A Alonso, A Schonichen, A Subtil, A Tierrez, A Yoneda, AB Hall, AB Jaffe, AD Hoppe, AL Bishop, AP Wheeler, AR Frampton Jr., AS Alberts, B Qualmann, BJ Wallar, C Capo, C Cougoule, C Yang, CA Burnham, CM Haglund, CW Gourlay, D Howe, D Michaelson, D Michaelson, D Truong, Daniel E. Voth, DE Voth, DJ Hackam, DM Underhill, DM Waag, DT Brandt, E Alix, E Caron, E Colucci-Guyon, E Lemichez, EJ van Schaik, EM Rosales, EN Firat-Karalar, F Li, F Matsumura, F Niedergang, G Kaplan, GD Fairn, H Bierne, H Bierne, H Genth, HJ Newton, IM Olazabal, J Dellacasagrande, J Faix, J Hanisch, J Pizarro-Cerda, J Pizarro-Cerda, JA McDonough, JA Swanson, JC Patel, JC Patel, JE Heindl, Jesús S. Distel, JG Duman, JG Kim, K Aktories, K Bhadriraju, L Hodgson, LA Allen, M Aguilera, M Amano, M Amano, M Fernandez-Borja, M Kaksonen, M Ladwein, María I. Colombo, MG Gutierrez, Milton O. Aguilera, ML Gardel, N Ramalingam, N Watanabe, N Watanabe, NA Khan, O Billker, O Pertz, O Pertz, OB Matas, OG Baca, OG Baca, P Aspenstrom, P Cossart, P Croise, P Hotulainen, PJ Roberts, PS Romano, R Fox, RA Carabeo, RC May, RC May, Rodolfo M. Ortiz Flores, Romina P. Salinas, RS Flannagan, S Meconi, SJ Heasman, SK Hussain, T Dubois, T Tominaga, V Benard, VC Tam, W Beron, Walter Berón, WI Goh, X Chi, XD Ren, Z Woldehiwet   +109 more
core   +17 more sources

On the role of residue phosphorylation in 14-3-3 partners: AANAT as a case study [PDF]

, 2017
Twenty years ago, a novel concept in protein structural biology was discovered: the intrinsically disordered regions (IDRs). These regions remain largely unstructured under native conditions and the more are studied, more properties are attributed to ...
Bustos, Diego Martin, Masone, Diego Fernando, Uhart, Marina   +2 more
core   +5 more sources

The rab3A-22A chimera prevents sperm exocytosis by stabilizing open fusion pores [PDF]

, 2016
At the final stage of exocytotis, a fusion pore opens between the plasma and a secretory vesicle membranes; typically, when the pore dilates the vesicle releases its cargo.
Bustos, Matias Alberto, De la Iglesia, Paola X., Lucchesi, Ornella, Pocognoni, Cristián Adrián, Quevedo, María Florencia, Tomes, Claudia Nora   +5 more
core   +1 more source

The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions. [PDF]

, 2015
Given their obligate intracellular lifestyle, Chlamydia trachomatis ensure their access to multiple host sources of essential lipids by interfering vesicular transport.
Capmany, Anahi, Damiani, Maria Elena, Gambarte Tudela, Julian Alberto, Goud, Bruno, Miserey Lenkei, Stephanie, Quintero, Cristian Andres, Raposo, Graça, Romao, Maryse   +7 more
core   +1 more source

Epac, Rap and Rab3 act in concert to mobilize calcium from sperm's acrosome during exocytosis [PDF]

, 2014
BACKGROUND: Exocytosis of sperm's single secretory granule or acrosome (acrosome reaction, AR) is a highly regulated event essential for fertilization. The AR begins with an influx of calcium from the extracellular milieu and continues with the synthesis
Bustos, Matias Alberto, Lucchesi, Ornella, Ruete, María Celeste, Tomes, Claudia Nora   +3 more
core   +1 more source

Changes in renal WT-1 expression preceding hypertension development [PDF]

, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica, Calvo, Juan Pablo, Casarotto, Mariana, Cuello Carrión, Fernando Darío, Ferder, León, Fornes, Miguel Walter, García, Isabel Mercedes, Manucha, Walter Ariel Fernando, Mazzei, Luciana Jorgelina   +8 more
core   +2 more sources

Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]

, 2018
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo, A Montalvetti, A Rassi, AB Penissi, AE Eakin, AH Kolien, AJ Solari, AM Sánchez, Ana Yecê das Neves Pinto, C Brack, CF Silva Da, D Gonzalez-Pacanowska, DA Campbell, DA Johnston, DJ Hammond, DV Andrade, E Bontempi, E Lozano, E Lozano, E Lozano, EO Ogbadoiyi, ES Garcia, ES Lozano, F Dos Reis, FR Opperdoes, FR Opperdoes, FR Opperdoes, FS Laranja, H Meyer, H Meyer, J Aldunate, J Lukes, J McKerrow, J Mottram, JA Urbina, JA Urbina, JA Urbina, JA Urbina, JC Engel, JC Linder, JCP Dias, JCP Dias, JD Bergstrom, JD Maya, JF Turrens, JJ Marr, JL Avila, JL Avila, Juliano de Toledo, K Lazardi, K Miranda, K Miranda, KH Lee, L Simpson, LV Muschietti, M Meirelles, M Nieto, MC Elias, MCQB Elias, MR Ariyanayagam, MR Ariyanayagam, NM Sayed El, O Campetella, OS Giordano, OS Giordano, P Barrera, P Webster, PF Pimenta, R Docampo, S Sepúlveda-Boza, SD Brengio, SR Wilkinson, T Souto-Padron, T Souto-Padron, T Souto-Padron, T Souto-Padron, TA Shapiro, TS Tiuman, V Jimenez-Ortiz, V Sülsen, VP Sülsen, VP Sülsen, VV Costantino, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, Wanderley de Souza, WE Gutteridge   +90 more
core   +1 more source

Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family [PDF]

, 2016
Posttranslational regulation of protein function is an ubiquitous mechanism in eukaryotic cells. Here, we analyzed biological properties of nodes and edges of a human protein-protein interaction phosphorylation-based network, especially of those nodes ...
Bustos, Diego Martin, Flores, Gabriel, Uhart, Marina   +2 more
core   +1 more source

Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment

Journal of Experimental & Clinical Cancer Research, 2019
Background Skin cutaneous melanoma (SKCM) is the most lethal form of skin cancer and while incidence rates are declining for most cancers, they have been steadily rising for SKCM.
Elena Gómez-Abenza, Sofía Ibáñez-Molero, Diana García-Moreno, Inmaculada Fuentes, Leonard I. Zon, Maria C. Mione, María L. Cayuela, Chiara Gabellini, Victoriano Mulero   +8 more
doaj   +1 more source

Ultrastructure and morphometry of ovarian follicles in the armadillo Chaetophractus villosus (Mammalia, Dasypodidae)

Brazilian Journal of Biology
Ultrastructural and morphometric changes in oocyte and surrounding granulosa cells during armadillo follicular growth are described. Primordial, intermediary, early and late primary, secondary, tertiary and preovulatory Graafian follicles were found ...
S. M. CODÓN, S. G. ESTECONDO, E. J. GALÍNDEZ, E. B. CASANAVE   +3 more
doaj   +1 more source