Results 51 to 60 of about 33,964 (160)

Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship [PDF]

open access: yes, 2018
Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated.
Agüero, Rocio   +4 more
core  

Melanisation in Salmonid Skeletal Muscle: A Review

open access: yesJournal of Fish Diseases, Volume 48, Issue 3, March 2025.
ABSTRACT Melanisation can occur in the musculature of fish. A well‐known form is the melanised focal changes, or ‘black spots’, in the fillet of farmed Atlantic salmon (Salmo salar). The aetiology of black spots has not been fully determined, though recent research has emphasised the role of fat necrosis in their development.
Håvard Bjørgen   +2 more
wiley   +1 more source

Rewriting nuclear epigenetic scripts in mitochondrial diseases as a strategy for heteroplasmy control

open access: yesEMBO Molecular Medicine
Mitochondrial diseases, caused by mutations in nuclear or mitochondrial DNA (mtDNA), have limited treatment options. For mtDNA mutations, reducing the mutant-to-wild-type mtDNA ratio (heteroplasmy shift) is a promising strategy, though it currently faces
María J Pérez   +6 more
doaj   +1 more source

Interaction of mycobacterium tuberculosis with the host cells: a focus in the molecular mechanism involved in trafficking and autophagy [PDF]

open access: yes, 2018
Tuberculosis (TB) is an ancient disease remaining a serious health threat worldwide. It is caused by Mycobacterium tuberculosis (Mtb), an acid-fast bacilli, non-sporulated, slow-growing, immobile and aerobic.
Colombo, Maria Isabel   +2 more
core  

Full‐spectrum cannabidiol reduces UVB damage through the inhibition of TGF‐β1 and the NLRP3 inflammasome

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 1, Page 83-105, January/February 2025.
Photoprotective and antiinflammatory benefits of full‐spectrum cannabidiol (FS‐CBD) against UVB‐induced cellular death were examined in this study. FS‐CBD protected against UVB‐induced bacterial death for 30 min. FS‐CBD protected against UVB‐induced cells, in an in vitro keratinocyte cell model.
I. M. Urrutia‐Ortega   +8 more
wiley   +1 more source

Evidence of haptoglobin in the porcine female genital tract during oestrous cycle and its effect on in vitro embryo production

open access: yesScientific Reports, 2021
Recent evidence supports involvement of the acute phase protein haptoglobin in numerous events during mammalian reproduction. The present study represents an in-depth investigation of haptoglobin expression and secretion in the porcine oviduct and uterus,
Francisco A. García-Vázquez   +10 more
doaj   +1 more source

Evidence for maternal transmission fo a putative endosymbiont in the digestive gland of Pomacea canaliculata (Architaenioglossa, Ampullariidae) [PDF]

open access: yes, 2017
The digestive gland of the apple snail Pomacea canaliculata lodges two types of pigmented corpuscles (identified as C and K corpuscles) which has been proposed as endosymbiont/s.
Castro Vazquez, Alfredo Juan   +2 more
core  

Evaluating use of two‐step International Ovarian Tumor Analysis strategy to classify adnexal masses identified in pregnancy: pilot study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 6, Page 808-817, December 2024.
ABSTRACT Objectives The primary aim was to validate the International Ovarian Tumor Analysis (IOTA) benign simple descriptors (BDs) followed by the Assessment of Different NEoplasias in the adneXa (ADNEX) model, if BDs cannot be applied, in a two‐step strategy to classify adnexal masses identified during pregnancy. The secondary aim was to describe the
J. Barcroft   +8 more
wiley   +1 more source

Microalgae and cyanobacteria as microbial substrate and their influence on the potential postbiotic capability of a bacterial probiotic

open access: yesMicrobial Biotechnology, Volume 17, Issue 11, November 2024.
Postbiotic are bacterial metabolites, including extracellular products (ECP), and can be affected by various factors such as cultivation conditions which influence bacterial metabolism. The present work uses a microalgae‐/cyanobacteria‐supplemented media as a novel substrate for growing the probiotic Shewanella putrefaciens SpPdp11, analysing and ...
Marta Domínguez‐Maqueda   +10 more
wiley   +1 more source

Geriatría: Asignatura pendiente

open access: yesRevista de la Facultad de Ciencias Médicas de Córdoba, 2019
Los gerontes necesitan médicos competentes en fisiología y patologías del anciano. Objetivo: relevar la enseñanza de Geriatría, intención de los alumnos de 10 y 4° año de especializarse en Geriatría y opinión sobre importancia y momento en que deberían ...
Norberto D Bassan   +4 more
doaj  

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