Results 181 to 190 of about 5,806,032 (291)

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Endoscopic Ultrasound-Guided Tissue Acquisition for Parapharyngeal Space Lesions. [PDF]

Dig Endosc
Hikichi T, Nakamura J, Kato T, Yanagita T.   +3 more
europepmc   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Transbronchial Lung Cryobiopsy and Awake Video-Assisted Thoracic Surgery in Interstitial Lung Disease: Complementary Roles in a Stepwise Diagnostic Approach. [PDF]

Diagnostics (Basel)
Masi U, Sanduzzi Zamparelli A, Sanduzzi Zamparelli S.   +2 more
europepmc   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

MRI in MASLD: technical foundations and guideline-based applications. [PDF]

BMJ Open Gastroenterol
Pu J, Zhu L, Wu Y, Ping F, Xu J, Zhou K, Wang X, Pan J.   +7 more
europepmc   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Visible and near-infrared spectroscopic method for correlative joint tissue analysis and visual and histologic grading. [PDF]

MethodsX
Spurri A, Kust SJ, Arnold A, Baylin P, Allen N, Fentaw B, Barnes L, Proca D, Pleshko N.   +8 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

New technologies in oral reconstructive medicine: Consensus report of the AAP/OF/SEPA Workshop. [PDF]

J Periodontol
Sanz M, Ivanovski S, Nart J, Schwarz F, Wang HL, Aghaloo TL, Al-Nawas B, Avila-Ortiz G, Barootchi S, Blanco J, Blasi G, Donos N, Feher B, Dragan IF, Geisinger ML, Guerrero A, Ioannidou E, Kaigler D, Hernandez-Kapila Y, Kumar PS, Levin L, Liñares A, Mandelaris GA, Matesanz-Pérez P, Monje A, Montero E, Ortiz-Vigón A, Otomo-Corgel J, Pirih FQ, Ramanauskaite A, Rocchietta I, Ruiz-Magaz V, Saito H, Sánchez N, Sanz Esporrin J, Sculean A, Thieringer FM, Thoma DS, Valles C, Velásquez D, Wu DT, Giannobile WV.   +41 more
europepmc   +1 more source