Results 191 to 200 of about 264,298 (261)

SKUF Protocol: Slice, Keep, Unwrap, Fuse-A Pilot Multimodal Approach to Cardiac Innervation Mapping. [PDF]

Diagnostics (Basel)
Makarov I, Solovyova O, Starshinova A, Kudlay D, Mitrofanova L.   +4 more
europepmc   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Characterization of Ovine Intervertebral Disc Health Across the Lifespan: Relationships Between Quantitative MRI, Radiological, Histological, Biochemical, and Biomechanical Assessments. [PDF]

JOR Spine
Yusuf Y, Abbott RE, Buko EO, Chase KL, Falck AL, Pendleton D, McDermott KA, Armstrong AR, Bradley EW, Johnson CP, Ellingson AM.   +10 more
europepmc   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Progress in the application of 68Ga-Pentixafor PET/CT in lung cancer: a review. [PDF]

Oncol Rev
Liu L, Zhang J.
europepmc   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Integrating histopathology and immune marker analysis for machine learning-based colorectal cancer prognostics. [PDF]

Diagn Pathol
Saadh MJ, Saeed TN, Alfarttoosi KH, Ballal S, Nayak PP, Singh A, Kavitha V, Kubaev A, Taher WM, Alwan M, Jawad MJ, Ali Al-Nuaimi AM, Farhood B.   +12 more
europepmc   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Temporal dynamics of neuroplasticity and neurodegeneration in the central auditory system following noise-induced hearing loss: a multimodal imaging and histological study. [PDF]

Acta Neuropathol Commun
Giménez-Esbrí V, Schwitzer S, Mueller S, Koch S, Foddis M, Donat S, Schmoranzer J, Gimber N, Zeqiraj J, Basta D, Boehm-Sturm P, Gröschel M.   +11 more
europepmc   +1 more source